LRP10

LRP10
Identifiers
Aliases	LRP10 , LRP9, MST087, MSTP087, LDL receptor related protein 10, LRP-10
External IDs	OMIM: 609921 MGI: 1929480 HomoloGene: 8535 GeneCards: LRP10
Gene location (Human)
Chr.	Chromosome 14 (human)
End	22,881,713 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	54,708,954 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; right coronary artery; ; pancreatic ductal cell; ; gastric mucosa; ; popliteal artery; ; gallbladder; ; ascending aorta; ; left coronary artery; ; gums; ; blood;
	Top expressed in
	molar; ; pyloric antrum; ; superior surface of tongue; ; crypt of lieberkuhn of small intestine; ; large intestine; ; parotid gland; ; colon; ; left colon; ; epithelium of stomach; ; lacrimal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	low-density lipoprotein particle receptor activity ;
Cellular component	integral component of membrane ; clathrin-coated pit ; membrane ;
Biological process	inner ear development ; lipid transport ; endocytosis ; receptor-mediated endocytosis ; lipid metabolism ;
	Sources:Amigo / QuickGO
Orthologs
	26020
	65107
	ENSG00000197324
	ENSMUSG00000022175
	Q7Z4F1
	Q7TQH7
	NM_014045 ; NM_001329226
	NM_022993
	NP_001316155 ; NP_054764
	NP_075369
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated November 29, 2023

Low-density lipoprotein receptor-related protein 10 is a protein that in humans is encoded by the LRP10 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000197324 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022175 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
↑ "Entrez Gene: LRP10 low density lipoprotein receptor-related protein 10".

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID 8889548.
Sugiyama T, Kumagai H, Morikawa Y, et al. (2001). "A novel low-density lipoprotein receptor-related protein mediating cellular uptake of apolipoprotein E-enriched beta-VLDL in vitro". Biochemistry. 39 (51): 15817–25. doi:10.1021/bi001583s. PMID 11123907.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Tomarev SI, Wistow G, Raymond V, et al. (2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Invest. Ophthalmol. Vis. Sci. 44 (6): 2588–96. doi:10.1167/iovs.02-1099. PMID 12766061.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi: 10.1073/pnas.0404089101 . PMC 524842 . PMID 15498874.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000197324 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022175 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9110174-5] Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.

[entrez-6] "Entrez Gene: LRP10 low density lipoprotein receptor-related protein 10".

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[2]

[3]

[4]

[5]

[6]

v t e Lipids: lipoprotein particle metabolism
Lipoprotein particle classes and subclasses	delivery of TGs: Chylomicron VLDL delivery of C and CE: IDL LDL lb LDL sd LDL Lp(a) HDL Remnant cholesterol
Apolipoproteins	APOA 1 2 4 5 APOB APOC 1 2 3 4 APOD APOE APOH SAA SAA1
Extracellular enzymes	LCAT LIPC LPL
Lipid transfer proteins	CETP MTTP PLTP
Cell surface receptors	HDL: SCARB1 IDL: LRP LRP1 LRP1B LRP2 LRP3 LRP4 LRP5 LRP5L LRP6 LRP8 LRP10 LRP11 LRP12 LDL: LDLR LRPAP1
ATP-binding cassette transporter	ABCA1 ABCG5 ABCG8

LRP10

Related Research Articles

References

Further reading