LRP3

Last updated
LRP3
Identifiers
Aliases LRP3 , LDL receptor related protein 3
External IDs OMIM: 603159 MGI: 3584516 HomoloGene: 1745 GeneCards: LRP3
Gene location (Human)
Ideogram human chromosome 19.svg
Chr. Chromosome 19 (human) [1]
Human chromosome 19 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 19q13.11Start33,177,603 bp [1]
End33,208,864 bp [1]
Orthologs
SpeciesHumanMouse
Entrez

4037

435965

Ensembl

ENSG00000130881

ENSMUSG00000001802

UniProt

O75074

n/a

RefSeq (mRNA)

NM_002333

NM_001024707

RefSeq (protein)

NP_002324

n/a

Location (UCSC) Chr 19: 33.18 – 33.21 Mb Chr 7: 35.2 – 35.22 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Low density lipoprotein receptor-related protein 3 (LRP-3) is a protein that in humans is encoded by the LRP3 gene. [5]

Related Research Articles

LDL-receptor-related protein-associated protein

Low density lipoprotein receptor-related protein-associated protein 1 also known as LRPAP1 or RAP is a chaperone protein which in humans is encoded by the LRPAP1 gene.

OLR1

Oxidized low-density lipoprotein receptor 1 also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a protein that in humans is encoded by the OLR1 gene.

LRP2

Low density lipoprotein-related protein 2 also known as LRP2 or megalin is a protein which in humans is encoded by the LRP2 gene.

LRP1

Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells involved in receptor-mediated endocytosis. In humans, the LRP1 protein is encoded by the LRP1 gene. LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and cell motility, and diseases, such as neurodegenerative diseases, atherosclerosis, and cancer.

GPR6

G protein-coupled receptor 6, also known as GPR6, is a protein which in humans is encoded by the GPR6 gene.

GPR12

Probable G-protein coupled receptor 12 is a protein that in humans is encoded by the GPR12 gene.

FZD1

Frizzled-1 is a protein that in humans is encoded by the FZD1 gene.

GPR50

G protein-coupled receptor 50 is a protein which in humans is encoded by the GPR50 gene.

GPRC5B

G-protein coupled receptor family C group 5 member B is a protein that in humans is encoded by the GPRC5B gene.

LRP5

Low-density lipoprotein receptor-related protein 5 is a protein that in humans is encoded by the LRP5 gene. LRP5 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. Mutations in LRP5 can lead to considerable changes in bone mass. A loss-of-function mutation causes osteoporosis-pseudoglioma, while a gain-of-function mutation causes drastic increases in bone mass.

LRP6

Low-density lipoprotein receptor-related protein 6 is a protein that in humans is encoded by the LRP6 gene. LRP6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway.

MMP16

Matrix metalloproteinase-16 is an enzyme that in humans is encoded by the MMP16 gene.

ST7

Suppressor of tumorigenicity protein 7 is a protein that in humans is encoded by the ST7 gene. ST7 orthologs have been identified in all mammals for which complete genome data are available.

MMP17

Matrix metalloproteinase-17 (MMP-17) also known as membrane-type matrix metalloproteinase 4 is an enzyme that in humans is encoded by the MMP17 gene.

OR3A3

Olfactory receptor 3A3 is a protein that in humans is encoded by the OR3A3 gene.

LRP1B

Low-density lipoprotein receptor-related protein 1B is a protein that in humans is encoded by the LRP1B gene.

LMX1A

LIM homeobox transcription factor 1, alpha, also known as LMX1A, is a protein which in humans is encoded by the LMX1A gene.

LRP10

Low-density lipoprotein receptor-related protein 10 is a protein that in humans is encoded by the LRP10 gene.

MMP15

Matrix metalloproteinase 15 also known as MMP15 is an enzyme that in humans is encoded by the MMP15 gene.

Low-density lipoprotein receptor-related protein 4

Low-density lipoprotein receptor-related protein 4 (LRP-4), also known as multiple epidermal growth factor-like domains 7 (MEGF7), is a protein that in humans is encoded by the LRP4 gene. LRP-4 is a member of the Lipoprotein receptor-related protein family and may be a regulator of Wnt signaling.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000130881 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001802 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ "Entrez Gene: Low density lipoprotein receptor-related protein 3" . Retrieved 2011-10-05.

Further reading


This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.