Ladero was an unincorporated community in southern Wayne County, in the U.S. state of Missouri. [1] The community is on Otter Creek approximately one mile (two kilometers) west of US Route 67 and the St. Francis River. [2]
Ladero had its start when the railroad was extended to that point. [3] It is unknown why the name "Ladero" was applied to this community. [3]