Mannonate dehydratase

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mannonate dehydratase
Identifiers
EC no. 4.2.1.8
CAS no. 9024-31-1
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BRENDA BRENDA entry
ExPASy NiceZyme view
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MetaCyc metabolic pathway
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NCBI proteins

The enzyme mannonate dehydratase (EC 4.2.1.8) catalyzes the chemical reaction

D-mannonate 2-dehydro-3-deoxy-D-gluconate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-mannonate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming). Other names in common use include mannonic hydrolase, mannonate hydrolyase, altronic hydro-lyase, altronate hydrolase, D-mannonate hydrolyase, and D-mannonate hydro-lyase. This enzyme participates in pentose and glucuronate interconversions.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1TZ9.

Related Research Articles

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References