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Names | |
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IUPAC name (2E)-(5-hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene ethanoic acid | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
MeSH | NCS-382 |
PubChem CID | |
UNII | |
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Properties | |
C13H14O3 | |
Molar mass | 218.248 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
NCS-382 is a moderately selective antagonist for the GHB receptor. [1] [2] It blocks the effects of GHB in animals and has both anti-sedative and anticonvulsant effects. [3] [4] [5] It has been proposed as a treatment for GHB overdose in humans as well as the genetic metabolic disorder succinic semialdehyde dehydrogenase deficiency (SSADHD), but has never been developed for clinical use. [6]