Nephrocystin-1 is a protein that in humans is encoded by the NPHP1 gene. [5]
This gene encodes a protein with src homology domain 3 (SH3) patterns. Mutations in this gene cause familial juvenile nephronophthisis. [5]
NPHP1 has been shown to interact with BCAR1, [6] [7] PTK2B, [7] Filamin [8] and INVS. [9]
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