Small nuclear ribonucleoprotein G is a protein that in humans is encoded by the SNRPG gene. [3] [4]
Small nuclear ribonucleoprotein G is a protein that in humans is encoded by the SNRPG gene. [3] [4]
SNRPG has been shown to interact with DDX20 [5] and TACC1. [6]
snRNPs, or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs. The action of snRNPs is essential to the removal of introns from pre-mRNA, a critical aspect of post-transcriptional modification of RNA, occurring only in the nucleus of eukaryotic cells. Additionally, U7 snRNP is not involved in splicing at all, as U7 snRNP is responsible for processing the 3′ stem-loop of histone pre-mRNA.
Gideon Dreyfuss is an American biochemist, the Isaac Norris Professor of Biochemistry and Biophysics at the University of Pennsylvania School of Medicine, and an investigator of the Howard Hughes Medical Institute. He was elected to the National Academy of Sciences in 2012.
U1 spliceosomal RNA is the small nuclear RNA (snRNA) component of U1 snRNP, an RNA-protein complex that combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs. Splicing, or the removal of introns, is a major aspect of post-transcriptional modification, and takes place only in the nucleus of eukaryotes.
Survival of motor neuron or survival motor neuron (SMN) is a protein that in humans is encoded by the SMN1 and SMN2 genes.
rRNA 2'-O-methyltransferase fibrillarin is an enzyme that in humans is encoded by the FBL gene.
Small nuclear ribonucleoprotein Sm D1 is a protein that in humans is encoded by the SNRPD1 gene.
Small nuclear ribonucleoprotein-associated proteins B and B' is a protein that in humans is encoded by the SNRPB gene.
Small nuclear ribonucleoprotein Sm D2 is a protein that in humans is encoded by the SNRPD2 gene. It belongs to the small nuclear ribonucleoprotein core protein family, and is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Small nuclear ribonucleoprotein E is a protein that in humans is encoded by the SNRPE gene.
Small nuclear ribonucleoprotein Sm D3 is a protein that in humans is encoded by the SNRPD3 gene.
Gem-associated protein 2 (GEMIN2), also called survival of motor neuron protein-interacting protein 1 (SIP1), is a protein that in humans is encoded by the GEMIN2 gene.
Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3 (GEMIN3), is an enzyme that in humans is encoded by the DDX20 gene.
Small nuclear ribonucleoprotein F is a protein that in humans is encoded by the SNRPF gene.
U2 small nuclear ribonucleoprotein B is a protein that in humans is encoded by the SNRPB2 gene.
U6 snRNA-associated Sm-like protein LSm7 is a protein that in humans is encoded by the LSM7 gene.
H/ACA ribonucleoprotein complex subunit 1 is a protein that in humans is encoded by the GAR1 gene.
U1 small nuclear ribonucleoprotein C is a protein that in humans is encoded by the SNRPC gene.
Transforming acidic coiled-coil-containing protein 1 is a protein that in humans is encoded by the TACC1 gene.
Gem-associated protein 4 is a protein that in humans is encoded by the GEMIN4 gene.
Gem-associated protein 5 is a protein that in humans is encoded by the GEMIN5 gene.
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