Salicylate decarboxylase

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Salicylate decarboxylase
Identifiers
EC no. 4.1.1.91
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
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NCBI proteins

Salicylate decarboxylase (EC 4.1.1.91, salicylic acid decarboxylase, Scd) is an enzyme with systematic name salicylate carboxy-lyase. [1] This enzyme catalyses the following chemical reaction

salicylate phenol + CO2

In the reverse direction the enzyme catalyses the regioselective carboxylation of phenol into salicylate.

References

  1. Kirimura K, Gunji H, Wakayama R, Hattori T, Ishii Y (April 2010). "Enzymatic Kolbe-Schmitt reaction to form salicylic acid from phenol: enzymatic characterization and gene identification of a novel enzyme, Trichosporon moniliiforme salicylic acid decarboxylase". Biochemical and Biophysical Research Communications. 394 (2): 279–84. Bibcode:2010BBRC..394..279K. doi:10.1016/j.bbrc.2010.02.154. PMID   20188702.