U.S. Route 25 or U.S. Highway 25 (US 25) is a north–south United States Numbered Highway that runs for 750 miles (1,210 km) in the Southern and Midwestern U.S. Its southern terminus is in Brunswick, Georgia, from where it proceeds mostly due north, passing through the cities of Augusta, Georgia; Greenville, South Carolina; and Asheville, North Carolina, before dividing into two branches, known as US 25W and US 25E between Newport, Tennessee, and North Corbin, Kentucky. After passing through Richmond and Lexington, Kentucky, it reaches its northern terminus at Ohio state line in Covington, Kentucky. The route is an important crossing of the Appalachian Mountains, and it is covered by three of the corridors of the Appalachian Development Highway System (ADHS). When the highway was originally established in 1926, the route extended from North Augusta, South Carolina, to Port Huron, Michigan. The southern end was extended to its current terminus in 1936, while the northern end was truncated in 1974.
State Route 56 is a 160.6-mile-long (258.5 km) state highway that runs south to north in Middle Tennessee, from the Alabama state line near Sherwood to the Kentucky state line near Red Boiling Springs.
U.S. Route 25E (US 25E) is the eastern branch of US 25 from Newport, Tennessee, where US 25 splits into US 25E and US 25W, to North Corbin, Kentucky, where the two highways rejoin. The highway, however, continues as US 25E for roughly two miles (3.2 km) until it joins Interstate 75 (I-75) in the Laurel County community of North Corbin at exit 29. The highway serves the Appalachia regions of Kentucky's Cumberland Plateau and the Ridge-and-Valley section of East Tennessee, including the urbanized areas of Corbin and Middlesboro in Kentucky and Morristown in Tennessee.
U.S. Route 25W (US 25W) is the western branch of US 25 from Newport, Tennessee, where US 25 splits into US 25E and US 25W, to North Corbin, Kentucky, where the two highways rejoin.
State Route 22 is a 172.8-mile long (278.1 km) south-to-north state highway in the western part of Tennessee, United States. It begins at the Mississippi state line in McNairy County, where the roadway continues as Mississippi Highway 2. It ends at the Kentucky state line in Lake County, when it crosses into the Kentucky Bend, a detached portion of Fulton County, Kentucky. The monument for the 1862 Battle of Island Number Ten in the American Civil War is located on SR 22, about 3 mi (4.8 km) north of Tiptonville.
State Route 66 is a state-maintained highway in eastern Tennessee, including a six-lane divided highway known as Winfield Dunn Parkway in Sevier County, a four-lane expressway in Hamblen and Jefferson counties and a two-lane rural collector through mountainous terrain continuing to the northeast terminus in Hancock County.
State Route 9 (SR 9) is a west-to-east state highway in the U.S. state of Tennessee that is 131.33 miles (211.36 km) long. It begins in Campbell County and ends in Cocke County. SR 9 is little-known by the general public by this designation as it is overlain by U.S. Route 25W and U.S. Route 25 east of Newport; the "9" designation is seen on mileposts. The entire route is located in East Tennessee. Despite running concurrent with a North-South US Route, Route 9 is signed as east-west.
State Route 131 is a south-to-north highway in the U.S. state of Tennessee that is 68.8 miles long. It is designated as a secondary route.
State Route 96 is an east–west and north–south highway in Middle Tennessee. The road begins in Dickson and ends in Granville. The current length is 126.7 mi (203.9 km). Along its path it goes through 10 counties. Locals mostly refer to it as Highway 96.
State Route 20 (SR 20) is a 143.04-mile (230.20 km) long east–west primary state highway that begins in Dyersburg and ending near Summertown. SR 20 is unsigned and concurrent with U.S. Route 412 (US 412) for its entire length, except for a short section between Hohenwald and Summertown. Along its route, SR 20 traverses parts of both Middle Tennessee and West Tennessee.
State Route 15 is a west–east route from Memphis to Monteagle. For much of its route it has an unsigned concurrency with U.S. Route 64. SR 15 does travel through the southern part of all three Grand Divisions of the state: West Tennessee, Middle Tennessee, and East Tennessee.
State Route 160 is a state highway in East Tennessee that has both four-lane expressway and two-lane rural collector sections. It serves as a arterial bypass route of US 11E/SR 34 in the city of Morristown in Hamblen County.
In Tennessee, U.S. Route 412 stretches for 181.93 miles (292.79 km) through the farmland of West Tennessee and the hills of Middle Tennessee, starting at the Missouri state line near Dyersburg and running to an interchange between I-65 and SR 99 in Columbia.
U.S. Route 31A is a 76.94-mile-long (123.82 km) alternate route of U.S. Route 31 that exists between Nashville and Pulaski, Tennessee. It is located entirely in Middle Tennessee and except for the Lewisburg bypass, where it is concurrent with SR 106, it is entirely concurrent with unsigned State Route 11.
State Route 33 is a primary and secondary route in East Tennessee. It runs 176 miles, from the Georgia state line in Polk County, northeast to the Virginia state line north of Kyles Ford in Hancock County. South of Maryville, SR 33 is a "hidden" route which shares a concurrency with US 411.
State Route 113 is a north–south state highway in East Tennessee.
State Route 53 (SR 53) is a north–south state highway that traverses six counties in Middle Tennessee. It is 113.5 miles (182.7 km) long.
State Route 28 is a state highway in the state of Tennessee, traversing the state in a north–south axis from south of Jasper to the Kentucky state line at Static.
State Route 35 is a north–south state highway in East Tennessee. The 81.35 miles (130.92 km) long state highway traverses Blount, Sevier, a small portion of Jefferson, Cocke, and Greene Counties. Most of the route is a secret, or hidden designation, as it runs concurrently with U.S. Highways in the area.
The East Tennessee Crossing Byway is a 83-mile (134 km) National Scenic Byway in the U.S. state of Tennessee. Established in 2009, it is one of the newest byways in the National Scenic Byway system. The scenic byway traverses mostly along an unsigned concurrency of U.S. Route 25E/State Route 32 (US 25E/SR 32) in East Tennessee.
US 25E at the Kentucky state line in the Cumberland Gap Tunnel at Cumberland Gap
