U.S. Route 411 (US 411) is an alternate parallel-highway associated with US 11. It extends for about 309.7 miles (498.4 km) from US 78 in Leeds, Alabama, to US 25W/US 70 in Newport, Tennessee. US 411 travels through northeastern Alabama, northwestern Georgia, and southeastern Tennessee. It is signed north-south, as with most highways that have odd numbers, but the route runs primarily in a northeast-southwest direction, and covers a more east-west mileage than it does north-south. Notable towns and cities along its route include Gadsden, Alabama; Rome, Georgia; Cartersville, Georgia; Maryville, Tennessee; Sevierville, Tennessee, and Newport, Tennessee.
State Route 56 is a 160.6-mile-long (258.5 km) state highway that runs south to north in Middle Tennessee, from the Alabama state line near Sherwood to the Kentucky state line near Red Boiling Springs.
U.S. Route 70N is a northern alternate to U.S. Route 70, passing through parts of Middle Tennessee and East Tennessee. It runs 86.0 miles (138.4 km) east–west from Lebanon to Crossville, connecting the cities of Carthage, Baxter, Cookeville, and Monterey.
State Route 22 is a 172.8-mile long (278.1 km) south-to-north state highway in the western part of Tennessee, United States. It begins at the Mississippi state line in McNairy County, where the roadway continues as Mississippi Highway 2. It ends at the Kentucky state line in Lake County, when it crosses into the Kentucky Bend, a detached portion of Fulton County, Kentucky. The monument for the 1862 Battle of Island Number Ten in the American Civil War is located on SR 22, about 3 mi (4.8 km) north of Tiptonville.
State Route 66 is a state-maintained highway in eastern Tennessee, including a six-lane divided highway known as Winfield Dunn Parkway in Sevier County, a four-lane expressway in Hamblen and Jefferson counties and a two-lane rural collector through mountainous terrain continuing to the northeast terminus in Hancock County.
State Route 9 (SR 9) is a west-to-east state highway in the U.S. state of Tennessee that is 131.33 miles (211.36 km) long. It begins in Campbell County and ends in Cocke County. SR 9 is little-known by the general public by this designation as it is overlain by U.S. Route 25W and U.S. Route 25 east of Newport; the "9" designation is seen on mileposts. The entire route is located in East Tennessee. Despite running concurrent with a North-South US Route, Route 9 is signed as east-west.
State Route 62 is a 87.5-mile-long (140.8 km) west-to-east highway in the U.S. state of Tennessee. It is designated as a primary route except for the short segment between SR 169 and its eastern terminus, which is secondary.
State Route 131 is a south-to-north highway in the U.S. state of Tennessee that is 68.8-mile (110.7 km) long. It is designated as a secondary route.
State Route 96 is an east–west and north–south highway in Middle Tennessee. The road begins in Dickson and ends in Granville. The current length is 126.7 mi (203.9 km). Along its path it goes through 10 counties. Locals mostly refer to it as Highway 96.
State Route 99 is a long east–west highway in Middle Tennessee. The route travels through large sections of rural areas and for most of the length is a secondary highway. The route begins near Waynesboro and ends in Bradyville after logging 126.7 mi (203.9 km) and passing through six counties.
State Route 76 (SR 76) is a state highway in Tennessee, traversing the state in a northeast-southwest axis from east of Memphis to north of Nashville. SR 76 is unique in that it actually changes its cardinal directions in Clarksville at the junction with US 41A and US 41A Bypass.
State Route 107 is a 78.77-mile (126.77 km) state highway in eastern Tennessee, United States. It begins at an intersection with Round Mountain Road south of Del Rio and ends at the North Carolina state line east of Unicoi, where it becomes NC 226.
U.S. Route 421 is a north–south United States highway that runs for 43.4 miles (69.8 km) in East Tennessee, connecting the cities of Mountain City and Bristol.
State Route 16 is a state highway in the U.S. state of Tennessee. Its southern terminus is at the Alabama state line, where it continues as State Route 79 in Alabama. From there, it continues to Winchester, where it becomes unsigned in a concurrency with U.S. Route 41A. This concurrency lasts until its northern terminus in Williamson County, at a junction with U.S. Route 31A.
State Route 32 is a state highway in East Tennessee. For most of its route, it is an unsigned companion route concurrent with U.S. Route 25E. The highway stretches 89 miles from the North Carolina state line to the Tennessee-Kentucky state line near the town of Cumberland Gap.
State Route 53 (SR 53) is a north–south state highway that traverses six counties in Middle Tennessee. It is 113.5 miles (182.7 km) long.
U.S. Route 231 in Tennessee runs north–south for 121.15 miles (194.97 km), entirely in Middle Tennessee, that starts south of Fayetteville at the Alabama state line, and ends north of Westmoreland at the Kentucky state line. For the majority of its length, between the Alabama state line and Trousdale County, it is concurrent with unsigned State Route 10.
State Route 46 is a north–south state highway located in Middle Tennessee. It mainly goes on a northwest to southeast course while passing through towns and cities such as Cumberland City, Dickson, Leipers Fork, along with mainly rural areas of Stewart, Houston, Dickson, Hickman and Williamson Counties.
State Route 64 (SR 64) is an east–west state highway in Middle Tennessee. The 50.43-mile-long (81.16 km) route goes from the Lewisburg area to rural western Cannon County via Shelbyville and Beech Grove.
State Route 35 is a north–south state highway in East Tennessee. The 81.35 miles (130.92 km) long state highway traverses Blount, Sevier, a small portion of Jefferson, Cocke, and Greene Counties. Most of the route is a secret, or hidden designation, as it runs concurrently with U.S. Highways in the area.
NC 208 near Southe Greene 
US 321 / SR 107 / SR 350 at Greeneville 
US 11E at Greeneville
I-81 near Romeo 
US 11W at Rogersville 
SR 70 at Blackwater, Virginia 
