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Names | |
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IUPAC name (3S,5S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol | |
Other names (5α)-cholest-8-en-3β-ol | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChemSpider | |
KEGG | |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
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Properties | |
C27H46O | |
Molar mass | 386.664 g·mol−1 |
Appearance | crystalline solid |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Zymostenol is an intermediate compound in the biosynthesis of cholesterol and other sterols. It is formed during the conversion of lanosterol to cholesterol, a critical metabolic pathway in animals, fungi, and some protozoa. [1]
Zymostenol is produced from 14-demethyl lanosterol via the action of sterol Δ8,7-sterol isomerase (emopamil binding protein, EBP). This step is part of the Bloch pathway of cholesterol biosynthesis, where zymostenol is further converted to zymosterol and then to 7-dehydrocholesterol, a direct precursor to cholesterol. [2] [3] [4] [5]