| (R)-4-hydroxyphenyllactate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.222 | ||||||||
| CAS no. | 101754-02-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
(R)-4-hydroxyphenyllactate dehydrogenase (EC 1.1.1.222) is an enzyme that catalyzes a chemical reaction
The substrates of this enzyme are (R)-3-(4-hydroxyphenyl)lactate and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 3-(4-hydroxyphenyl)pyruvate, reduced NADH, and a proton. [1] [2] [3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-3-(4-hydroxyphenyl)lactate:NAD(P)+ 2-oxidoreductase. Other names in common use include (R)-aromatic lactate dehydrogenase, and D-hydrogenase, D-aryllactate. This enzyme participates in tyrosine and phenylalanine catabolism.
