The 2006 season was the Arizona Cardinals' 87th in the National Football League (NFL), their 19th in Arizona and the third and final under head coach Dennis Green. The season began with the team trying to improve on their 5–11 record in 2005. They also moved into the Cardinals Stadium in Glendale, Arizona, the first-ever stadium in the United States with a retractable playing surface. The stadium was christened University of Phoenix Stadium on September 26, and managed to sell out every home game. Despite a somewhat promising start, the team suffered a few setbacks, including key losses to the Dallas Cowboys and most memorably the eventual NFC Champion Chicago Bears, and ended the season (again) at a disappointing 5–11 record. Head coach Dennis Green was fired after the season, replaced by Ken Whisenhunt.
The 2007 season was the Arizona Cardinals' 88th in the National Football League (NFL), their 20th in Arizona and their first under head coach Ken Whisenhunt. They improved upon their 5–11 record in 2006 after finishing last place in the NFC West, by finishing 8–8, but the failure of the Cardinals to qualify for the Super Bowl marked the 23rd consecutive year in which the Super Bowl did not include the team in whose region the game was being played in; Super Bowl XIV and Super Bowl XIX were the only postseasons with such an occurrence before 2007.
The 2008 season was the Arizona Cardinals' 89th in the National Football League (NFL), their 21st season in Arizona, and their second under head coach Ken Whisenhunt. The season marked the Cardinals' first Super Bowl appearance, coming as a result of their victory against the Philadelphia Eagles in the NFC Championship. The Cardinals slogan for the season was "Shock The World!" Riding the back of quarterback Kurt Warner, who had gone from being a backup for the St. Louis Rams in 1999 to leading the Greatest Show on Turf to a Super Bowl XXXIV victory, and franchise wide receiver Larry Fitzgerald, the Cardinals went on a playoff run for the ages after having won just one playoff game in the last sixty years, as Warner once again recreated the magic he had captured with the Rams.
The 1998 Arizona Cardinals season was the franchise's 100th season, 79th season in the National Football League (NFL) and the 11th in Arizona. The club posted its first winning record since 1984, appeared in the postseason for the first time since 1982, its first postseason appearance in a non-strike season since 1975, and won its first postseason game since 1947. It was the Cardinals' first playoff appearance in its tenure in Arizona. After shocking the 10–6 Dallas Cowboys in the opening round in which the Cardinals won 20–7, Arizona ended up losing to the 15–1 Minnesota Vikings, 41–21 in the Divisional round. Over the next ten seasons, the Cardinals fell out of contention. They returned to the playoffs following the 2008 season, including a Super Bowl appearance despite a similarly mediocre 9–7 record.
The 2005 season was the Arizona Cardinals' 86th in the National Football League (NFL), their 107th overall and their 18th in Arizona. The team was unable to improve upon their 6–10 record from the previous season, and failed to make the playoffs for the seventh year in a row.
The 2009 season was the Arizona Cardinals' 90th in the National Football League (NFL), their 22nd in Arizona and their third under head coach Ken Whisenhunt.
The 2010 season was the Arizona Cardinals' 91st in the National Football League (NFL) and their 23rd in Arizona. The Cardinals attempted to improve on their 10–6 record from 2009. But after a modest 3–2 start, the Cardinals fell apart by losing 9 of their remaining 11 contests. They were eliminated from postseason contention for the first time since 2007 in Week 15.
The 2012 season was the Arizona Cardinals' 93rd in the National Football League (NFL), their 25th in Arizona, and their sixth and final season under head coach Ken Whisenhunt. After a surprising 4–0 start, which included a major upset of the New England Patriots in week 2, the Cardinals lost 11 of their final 12 games, and missed the playoffs for a third consecutive season, resulting in the firing of head coach Ken Whisenhunt after six seasons. This was Rod Graves' last season as general manager of the Cardinals. A day after the final game of the regular season, he was fired after 6 seasons.
The 2013 season was the Arizona Cardinals' 94th in the National Football League (NFL), their 26th in Arizona and their first under head coach Bruce Arians. The team finished with a 10–6 record, which was the second time in 37 years that the team finished with at least 10 wins. The Cardinals doubled their win total from 2012, and were in playoff contention heading into the Week 17 regular season finale, but missed the playoffs for a fourth consecutive season.
The 2014 season was the Arizona Cardinals' 95th in the National Football League (NFL), their 27th in Arizona and their second under head coach Bruce Arians. Following an explosive 9–1 start to the regular season, they finished at 11–5, achieving their highest win total since 1975 when they were still in St. Louis. The Cardinals clinched their first playoff berth since 2009, and had a chance to become the first team to try to play the Super Bowl on their own home field, University of Phoenix Stadium. However, after season-ending injuries to Carson Palmer and Drew Stanton, they were forced to start third-string quarterback Ryan Lindley in the wild-card round, losing to the Carolina Panthers, 27–16, which was the first time since 1982 when they were in St. Louis that the Cardinals went one-and-done.
The 2015 season was the Arizona Cardinals' 96th in the National Football League (NFL), their 117th overall, their 28th in Arizona, their 10th playing home games at University of Phoenix Stadium and their third under head coach Bruce Arians. The Cardinals clinched their first NFC West title since 2009, in addition to the first 13-win season in franchise history. They also clinched a first round bye for the first time in franchise history.
The 2016 season was the Arizona Cardinals' 97th in the National Football League (NFL), their 118th overall, their 29th in Arizona, their 11th at University of Phoenix Stadium and their fourth under head coach Bruce Arians.
The 2017 season was the Arizona Cardinals' 98th in the National Football League (NFL), their 30th in Arizona and their 12th at University of Phoenix Stadium. It was also the fifth and final season under head coach Bruce Arians. The Cardinals played one road game in London at Twickenham Stadium against the Los Angeles Rams as one of the NFL London Games. They improved on a 7–8–1 season they had in 2016, finishing 8–8 as they spent most of the season alternating between wins and losses. However, they missed the playoffs for the second straight season.
The 2018 season was the Arizona Cardinals' 99th in the National Football League (NFL), their 31st in Arizona, and their only season under head coach Steve Wilks. During the off-season, State Farm purchased the naming rights to the Cardinals' home stadium and it was renamed from University of Phoenix Stadium to State Farm Stadium. Although former head coach Bruce Arians retired before the season began, he came out of retirement on January 8, 2019 to become the new coach of the Tampa Bay Buccaneers.
The 2019 season was the Arizona Cardinals' 100th in the National Football League (NFL), their 32nd in Arizona and their first under head coach Kliff Kingsbury, following the firing of former head coach Steve Wilks the previous season. During the offseason, the Cardinals' home stadium was renamed from University of Phoenix Stadium to State Farm Stadium. The Cardinals were one of two current teams, along with the Chicago Bears, who were among the 14 charter members of the American Professional Football Association, which later became the NFL, that celebrated its 100th season in 2019.
The 2020 season was the Arizona Cardinals' 101st in the National Football League (NFL), their 33rd in Arizona and their second under head coach Kliff Kingsbury. It was also the first full season since 1971 without the ownership of Bill Bidwill, who died during the 2019 season.
The 2021 season was the Arizona Cardinals' 102nd season in the National Football League (NFL), their 34th in Arizona and their third under head coach Kliff Kingsbury. They improved from their 8–8 season from the previous year with a 23–13 victory over the Seattle Seahawks in Week 11. The Cardinals started 7–0 for the first time in 47 years when they were based in St. Louis. With their week 11 win over their division rivals, the Seattle Seahawks, the Cardinals improved on their record from the previous year and clinched their first winning season since 2015. Despite a loss to the Indianapolis Colts in Week 16, the Cardinals clinched a playoff berth for the first time since 2015 after the Minnesota Vikings lost to the Los Angeles Rams.
The 2022 season was the Arizona Cardinals' 103rd in the National Football League (NFL), their 35th in Arizona, and their fourth and final under head coach Kliff Kingsbury. They attempted to become the third straight team in NFL history to host and win the Super Bowl as that year's Super Bowl was held at State Farm Stadium. However, they failed to improve upon their 11–6 record from the previous year after a Week 11 loss to the San Francisco 49ers and missed the postseason after a Week 15 loss against the Denver Broncos.
The 2023 season was the Arizona Cardinals' 104th season in the National Football League (NFL) and the first under new head coach Jonathan Gannon and general manager Monti Ossenfort. The Cardinals matched their 4–13 record from the previous year after an upset win over the Philadelphia Eagles in Week 17. The team also introduced new uniforms for the first time since the 2005 season.
The 2024 season is the Arizona Cardinals' 105th season in the National Football League (NFL), their 37th in Arizona and their second under the head coach/general manager tandem of Jonathan Gannon and Monti Ossenfort. The Cardinals improved on their 4–13 record from the previous 2 seasons following a Week 9 victory against the Chicago Bears. They are looking to make the playoffs after a 2-year absence and end their 8-year NFC West title drought.