3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase

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3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase
Identifiers
EC no. 1.3.1.87
Alt. namescis-dihydrodiol dehydrogenase, 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase
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3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase is an enzyme with systematic name 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate:NAD+ oxidoreductase. [1] It is produced by the gene hcaB . This enzyme catalyses the following chemical reaction:

(1) 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ 3-(2,3-dihydroxyphenyl)propanoate + NADH + H+
(2) (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD+ (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + NADH + H+

This enzyme catalyses a step in indegradation of phenylpropanoid compounds.

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References

  1. ↑ Díaz E, Ferrández A, García JL (June 1998). "Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12". Journal of Bacteriology. 180 (11): 2915–23. PMC   107259 . PMID   9603882.
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