3-hydroxyoctanoyl-(acyl-carrier-protein) dehydratase

The correct title of this article is 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase. The substitution of any brackets is due to technical restrictions.

3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase
Identifiers
EC no.	4.2.1.59
CAS no.	9030-85-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The enzyme 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59) catalyzes the chemical reaction

(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] ${\displaystyle \rightleftharpoons }$ oct-2-enoyl-[acyl-carrier-protein] + H₂O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase (oct-2-enoyl-[acyl-carrier protein]-forming). Other names in common use include D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase, D-3-hydroxyoctanoyl-acyl carrier protein dehydratase, beta-hydroxyoctanoyl-acyl carrier protein dehydrase, beta-hydroxyoctanoyl thioester dehydratase, beta-hydroxyoctanoyl-ACP-dehydrase, and (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase.

See also

• 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase

References

• Mizugaki M, Swindell AC, Wakil SJ (1968). "Intermediate- and long-chain beta-hydroxyacyl-ACP dehydrases from E coli fatty acid synthetase". Biochem. Biophys. Res. Commun. 33 (3): 520–7. Bibcode:1968BBRC...33..520M. doi:10.1016/0006-291X(68)90607-4. PMID   4881058.