Aortic rupture

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Aortic rupture
Aorta segments.svg
Aorta segments, with thoracic aorta in area marked in green.
Specialty Vascular surgery, cardiology, emergency medicine
Symptoms Abdominal pain, flank pain, or back pain
Complications Shock, anemia
Usual onsetAcute
Causes Ruptured aortic aneurysm, trauma
TreatmentSurgical repair
Prognosis Poor
DeathsUp to 90% of cases

Aortic rupture is the breakage of all walls of the aorta, the largest artery in the body. Aortic rupture is a rare, extremely dangerous condition that is considered a medical emergency. [1] The most common cause is an abdominal aortic aneurysm that has ruptured spontaneously. Aortic rupture is distinct from aortic dissection, which is a tear through the inner wall of the aorta that can block the flow of blood through the aorta to the heart or abdominal organs.

Contents

An aortic rupture can be classified according to its cause into one of the following main types:

Signs and symptoms

Patients with an aortic rupture typically present with a sudden onset of severe pain. In ruptures involving the thoracic aorta, patients often experience acute chest pain that may radiate to the back, whereas involvement of the abdominal aorta more frequently results in pain localized to the abdomen, flank, or lower back. The rapid blood loss can lead to signs of shock, such as low blood pressure, rapid heartbeat, pallor, and even loss of consciousness. Because the clinical presentation may overlap with other vascular emergencies such as Aortic dissection—timely diagnosis using imaging modalities (e.g., computed tomography) is critical to initiate appropriate management. [3]

Causes

Aortic rupture may result from several distinct etiologies. The most common mechanism involves the spontaneous rupture of an aneurysmal aorta; for example, weakening of the vessel wall due to an Abdominal aortic aneurysm or Thoracic aortic aneurysm can ultimately lead to rupture under elevated intraluminal pressure. In addition, aortic rupture may occur following blunt trauma, as seen in Traumatic aortic rupture, where high-energy impacts from vehicle collisions or significant falls produce differential deceleration forces that tear the aortic wall. On rare occasions, iatrogenic injury during medical or surgical procedures can also precipitate aortic rupture. [4]

Mechanism

Diagnosis

Diagnosis of a ruptured abdominal aortic aneurysm (rAAA) is challenging, with a wrong diagnosis occurring in between 32 and 42 % of cases. Such errors further increase the mortality risk due to incorrect first response and treatment. In cases of misdiagnosis, aortic rupture is often mistaken for ureteric colic and myocardial infarction (MI). [4]

Differential diagnosis

The primary differential diagnoses include cardiogenic shock, pleural effusion, pulmonary embolism, myocarditis, myocardial infarction, [5] but may also encompass acute gastritis, appendicitis, diverticulitis, gallstones, peptic ulcer disease and urinary tract infection as well. [1]

Prevention

This involves 2 main strategies: managing lifestyle risks (to prevent an aneurysm from forming or growing, and medical screening to catch potential issues before they become emergent. [6] [7] [8]

Lifestyle risks include:

Who should be screened?

Medical interventions:

Treatment

Treatments range according to the severity of the condition from monitoring to emergency surgical repair. [16] Treatments include:

Prognosis

An aortic rupture is a catastrophic medical emergency. People rarely survive such an injury. Mortality from aortic rupture is up to 90%. 65–75% of patients die before they arrive at the hospital and up to 90% die before they reach the operating room. [21] In non-emergent cases the survival rate is over 95%, for an emergent ruptured aorta it is between 50-70%. [16]

References

  1. 1 2 Jeanmonod, Donald; Yelamanchili, Varun S.; Jeanmonod, Rebecca (2024), "Abdominal Aortic Aneurysm Rupture", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID   29083705 , retrieved 2024-10-25
  2. Ruptured Aortic Aneurysm at Patient UK. Original Author: Laurence Knott. Current Version: Gurvinder Rull. Peer Reviewer: Hannah Gronow. Last Checked: 16/05/2012
  3. Jeanmonod, D., Yelamanchili, V. S., & Jeanmonod, R. (2024). Abdominal Aortic Aneurysm Rupture. In StatPearls. StatPearls Publishing.
  4. 1 2 Azhar, Bilal; Patel, Shaneel R.; Holt, Peter J.E.; Hinchliffe, Robert J.; Thompson, Matt M.; Karthikesalingam, Alan (August 2014). "Misdiagnosis of Ruptured Abdominal Aortic Aneurysm: Systematic Review and Meta-Analysis" . Journal of Endovascular Therapy. 21 (4): 568–575. doi:10.1583/13-4626MR.1. ISSN   1526-6028. PMID   25101588.
  5. "Aortic Dissection Differential Diagnoses". emedicine.medscape.com. Retrieved 2024-10-25.
  6. 1 2 "Abdominal aortic aneurysm - Symptoms and causes". Mayo Clinic. Retrieved 2025-12-17.
  7. 1 2 "What Is Aortic Dissection?". Cleveland Clinic. Archived from the original on 2025-09-18. Retrieved 2025-12-17.
  8. "Preventing Aortic Dissection". nyulangone.org. Retrieved 2025-12-17.
  9. "Aortic dissection-Aortic dissection - Symptoms & causes". Mayo Clinic. Retrieved 2025-12-17.
  10. "Preventing Aortic Dissection". nyulangone.org. Retrieved 2025-12-17.
  11. "Abdominal Aneurysm Screening Guidelines: 8 Essential Points for 2025". 2025-11-04. Retrieved 2025-12-17.
  12. "10 Tips to Help Reduce Your Risk of an Aortic Aneurysm This Valentine's Day". Bangkok Heart Hospital. 2025-12-11. Retrieved 2025-12-17.
  13. "Aortic Dissection". Cleveland Clinic. Retrieved 17 December 2025.
  14. "Living With Aortic Aneurysm | Mass General Brigham". www.massgeneralbrigham.org. Retrieved 2025-12-18.
  15. Levy, David; Sharma, Sanjeev; Farci, Fabiola; Le, Jacqueline K. (2025), "Aortic Dissection", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID   28722992 , retrieved 2025-12-18
  16. 1 2 "Thoracic aortic aneurysm - Diagnosis and treatment - Mayo Clinic". www.mayoclinic.org. Retrieved 2025-12-18.
  17. "Endovascular Repair of an Abdominal Aortic Aneurysm". John Hopkins Medicine. Retrieved 18 December 2025.
  18. Sidik, Abubakar I.; Dontsov, Vladislav V.; Khavandeev, Maxim L.; Esion, Grigorii A.; Karpenko, Ivan G.; Sobolev, Dmitriy; Hossain, Limon; Ilyas Shafii, Abdulmajid; Derrar, Ahlam; Najneen, Farjana; Ak, Gulten; Ghosh, Debraj; Parera, Oralee Bonifacio (2025-10-06). "Open vs. Endovascular Aortic Repair: Guidelines and Real-World Outcomes". Cor et Vasa. 67 (4): 493–504. doi:10.33678/cor.2025.065.
  19. Isselbacher, Eric M.; Preventza, Ourania; Hamilton Black, James; Augoustides, John G.; Beck, Adam W.; Bolen, Michael A.; Braverman, Alan C.; Bray, Bruce E.; Brown-Zimmerman, Maya M.; Chen, Edward P.; Collins, Tyrone J.; DeAnda, Abe; Fanola, Christina L.; Girardi, Leonard N.; Hicks, Caitlin W. (2022-12-13). "2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines". Circulation. 146 (24): e334 –e482. doi:10.1161/CIR.0000000000001106. ISSN   1524-4539. PMC   9876736 . PMID   36322642.
  20. "Thoracic aortic aneurysm - Diagnosis and treatment - Mayo Clinic". www.mayoclinic.org. Retrieved 2025-12-18.
  21. Brown, LC; Powell, JT (September 1999). "Risk factors for aneurysm rupture in patients kept under ultrasound surveillance. UK Small Aneurysm Trial Participants". Annals of Surgery. 230 (3): 289–96, discussion 296-7. doi:10.1097/00000658-199909000-00002. PMC   1420874 . PMID   10493476.