Arteriovenous fistula

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Arteriovenous fistula
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Illustration of an arteriovenous fistula
Specialty Cardiology   OOjs UI icon edit-ltr-progressive.svg

An arteriovenous fistula is an abnormal connection or passageway between an artery and a vein. [1] It may be congenital, surgically created for hemodialysis treatments, or acquired due to pathologic process, such as trauma or erosion of an arterial aneurysm. [2]

Contents

Clinical features

Pathological

Hereditary hemorrhagic telangiectasia is a condition where there is direct connection between arterioles and venules without intervening capillary beds, at the mucocutaneous region and internal bodily organs. Those who are affected by this conditions usually do not experience any symptoms. Difficulty in breathing is the most common symptom for those who experience symptoms. [3]

Just like berry aneurysm, a cerebral arteriovenous malformation can rupture causing subarachnoid hemorrhage. [4]

Causes

The cause of this condition include

Surgically created Cimino fistula is used as a vascular access for hemodialysis. Blood must be aspirated from the body of the patient, and since arteries are not easy to reach compared to the veins, blood may be aspirated from veins. The problem is that the walls of the veins are thin compared to those of the arteries. The AV fistula is the solution for this problem because, after 4–6 weeks, the walls of the veins become thicker due to the high arterial pressure. Thus, this vein can now tolerate needles during hemodialysis sessions.

Mechanism

When an arteriovenous fistula is formed involving a major artery like the abdominal aorta, it can lead to a large decrease in peripheral resistance. This lowered peripheral resistance causes the heart to increase cardiac output to maintain proper blood flow to all tissues. The physical manifestations of this typically consist of a relatively normal systolic blood pressure accompanied by decreased diastolic blood pressure, resulting in a wider pulse pressure.[ citation needed ]

Normal blood flow in the brachial artery is 85 to 110 milliliters per minute (mL/min). After the creation of a fistula, the blood flow increases to 400–500 mL/min immediately, and 700–1,000 mL/min within 1 month. A brachiocephalic fistula above the elbow has a greater flow rate than a radiocephalic fistula at the wrist. Both the artery and the vein dilate and elongate in response to the greater blood flow and shear stress, but the vein dilates more and becomes "arterialized". In one study, the cephalic vein increased from 2.3 mm to 6.3 mm diameter after 2 months. When the vein is large enough to allow cannulation, the fistula is defined as "mature". [7]

An arteriovenous fistula can increase preload. [8] AV shunts also decrease the afterload of the heart. This is because the blood bypasses the arterioles which results in a decrease in the total peripheral resistance (TPR). AV shunts increase both the rate and volume of blood returning to the heart.[ citation needed ]

Diagnosis

The diagnosis of this condition can be done via ultrasound[ citation needed ]

See also

Related Research Articles

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An arteriovenous malformation (AVM) is an abnormal connection between arteries and veins, bypassing the capillary system. Usually congenital, this vascular anomaly is widely known because of its occurrence in the central nervous system, but can appear anywhere in the body. The symptoms of AVMs can range from none at all to intense pain or bleeding, and they can lead to other serious medical problems.

<span class="mw-page-title-main">Cerebral arteriovenous malformation</span> Abnormal connection between the arteries and veins in the brain

A cerebral arteriovenous malformation is an abnormal connection between the arteries and veins in the brain—specifically, an arteriovenous malformation in the cerebrum.

<span class="mw-page-title-main">Hypertensive retinopathy</span> Damage to the eyes retina due to high blood pressure

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<span class="mw-page-title-main">Vascular disease</span> Medical condition

Vascular disease is a class of diseases of the vessels of the circulatory system in the body, including blood vessels – the arteries and veins, and the lymphatic vessels. Vascular disease is a subgroup of cardiovascular disease. Disorders in this vast network of blood and lymph vessels can cause a range of health problems that can sometimes become severe, and fatal. Coronary heart disease for example, is the leading cause of death for men and women in the United States.

In nephrology, vascular access steal syndrome is a syndrome caused by ischemia resulting from a vascular access device that was installed to provide access for the inflow and outflow of blood during hemodialysis.

Vascular access refers to a rapid, direct method of introducing or removing devices or chemicals from the bloodstream. In hemodialysis, vascular access is used to remove the patient's blood so that it can be filtered through the dialyzer. Three primary methods are used to gain access to the blood: an intravenous catheter, an arteriovenous fistula (AV) or a synthetic graft. In the latter two, needles are used to puncture the graft or fistula each time dialysis is performed.

A vascular malformation is a type of vascular anomaly. They may cause aesthetic problems as they have a growth cycle, and can continue to grow throughout life.

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The Nicoladoni–Branham sign is named after Carl Nicoladoni, who first noticed the phenomenon of the pulse slowing in a patient with right arm phlebarteriectasia when the brachialis artery proximal to it was compressed. In modern medicine, the sign is elicited when pressure is applied to an artery proximal to an arteriovenous fistula and said to be positive if the following occurs:

<span class="mw-page-title-main">Parkes Weber syndrome</span> Medical condition

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<span class="mw-page-title-main">Vein of Galen aneurysmal malformations</span> Medical condition

Vein of Galen aneurysmal malformations(VGAMs) and Vein of Galen aneurysmal dilations (VGADs) are the most frequent arteriovenous malformations in infants and fetuses. A VGAM consists of a tangled mass of dilated vessels supplied by an enlarged artery. The malformation increases greatly in size with age, although the mechanism of the increase is unknown. Dilation of the great cerebral vein of Galen is a secondary result of the force of arterial blood either directly from an artery via an arteriovenous fistula or by way of a tributary vein that receives the blood directly from an artery. There is usually a venous anomaly downstream from the draining vein that, together with the high blood flow into the great cerebral vein of Galen causes its dilation. The right sided cardiac chambers and pulmonary arteries also develop mild to severe dilation.

References

  1. "Arteriovenous Fistulas: Background, Pathophysiology, Etiology". 2017-01-07.
  2. "Arteriovenous fistula - Symptoms and causes". Mayo Clinic. Retrieved 2019-12-05.
  3. Meier NM, Foster ML, Battaile JT (June 2018). "Hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations: clinical aspects". Cardiovascular Diagnosis and Therapy. 8 (3): 316–324. doi: 10.21037/cdt.2017.12.07 . PMC   6039799 . PMID   30057878.
  4. Park, Myung K. (2002). Pediatric cardiology for practitioners. With a contribution by R. George Troxler (4th ed.). St. Louis: Mosby. ISBN   978-0-323-01444-1.
  5. 1 2 3 4 Kumar, Vinay; Abbas, Abul K.; Aster, Jon C.; Turner, Jerrold R.; Perkins, James A.; Robbins, Stanley L.; Cotran, Ramzi S., eds. (2021). Robbins & Cotran pathologic basis of disease (10th ed.). Philadelphia, PA: Elsevier. p. 487. ISBN   978-0-323-53113-9.
  6. Watson N, Jones H (2018). Chapman and Nakielny's Guide to Radiological Procedures. Elsevier. p. 228. ISBN   9780702071669.
  7. Vascular, Vol. 14, Supl. 1, Nov. 2006, p. S1
  8. "Pulmonary: Heart Failure". Archived from the original on 1 February 2009. Retrieved 2008-12-21.