Apolipoprotein C-IV

Last updated
APOC4
Identifiers
Aliases APOC4 , APO-CIV, APOC-IV, apolipoprotein C4
External IDs OMIM: 600745 MGI: 87878 HomoloGene: 1245 GeneCards: APOC4
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001646

NM_007385

RefSeq (protein)

NP_001637

NP_031411

Location (UCSC) Chr 19: 44.94 – 44.95 Mb Chr 7: 19.41 – 19.42 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Apolipoprotein C-IV, also known as apolipoprotein C4, is a protein that in humans is encoded by the APOC4 gene. [5] [6]

Contents

Function

APOC4 is a member of the apolipoprotein C gene family. It is expressed in the liver and has a predicted protein structure characteristic of the other genes in this family. APOC4 is a 3.3-kb gene consisting of 3 exons and 2 introns; it is located 0.5 kb 5' to the APOC2 gene. [5]

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Apolipoprotein F is a protein that in humans is encoded for by the APOF gene. The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol.

<span class="mw-page-title-main">Apolipoprotein O</span> Protein-coding gene in the species Homo sapiens

Apolipoprotein O also known as protein FAM121B is a protein that in humans is encoded by the APOO gene. APOO is a member of the apolipoprotein family.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000267467 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000074336 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: apolipoprotein C-IV".
  6. Allan CM, Walker D, Segrest JP, Taylor JM (July 1995). "Identification and characterization of a new human gene (APOC4) in the apolipoprotein E, C-I, and C-II gene locus". Genomics. 28 (2): 291–300. doi:10.1006/geno.1995.1144. PMID   8530039.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.