Pennsylvania Route 191 is a 111.54 mi (179.51 km)-long state highway in the U.S. state of Pennsylvania. The route, a major non-freeway corridor connecting the Lehigh Valley to the Pocono Mountains in eastern Pennsylvania, is designated from U.S. Route 22 in Brodhead near Bethlehem to the New York state line over the Delaware River at Hancock, New York.
U.S. Route 422 (US 422) is a 271-mile-long (436 km) spur route of US 22 split into two segments in the U.S. states of Ohio and Pennsylvania. The western segment of US 422 runs from downtown Cleveland, Ohio, east to Ebensburg, Pennsylvania. The eastern segment, located entirely within Pennsylvania, runs from Hershey east to King of Prussia, near Philadelphia. US 422 Business serves as a business route into each of four towns along the way.
Pennsylvania Route 29 is a 118-mile-long (190 km) north–south state highway that runs through most of eastern Pennsylvania.
Pennsylvania Route 352 is a 19-mile (31 km) north–south route that runs from U.S. Route 13 Business in Chester, Delaware County, north to US 30 in Frazer, Chester County. The route passes through suburban areas of Delaware and Chester counties west of Philadelphia, serving Parkside, Brookhaven, Elwyn, Lima, Gradyville, and Goshenville. PA 352 is a four- to five-lane road between Brookhaven and US 1, otherwise it is generally a two-lane road. The route intersects Interstate 95 (I-95) in Chester and US 1 near Lima at interchanges. PA 352 was first designated by 1928 to run between its current termini. A portion of the route between Brookhaven and US 1 was realigned to a straighter alignment in the 1950s. By 1980, PA 352 was realigned to a short concurrency with PA 3 to avoid intersecting it at a sharp angle.
Pennsylvania Route 63 (PA 63) is a 37.4-mile-long (60.2 km) state highway located in the Philadelphia, Pennsylvania, area. The western terminus of the route is at PA 29 in Green Lane, Montgomery County. The eastern terminus is at Interstate 95 (I-95) in Bensalem Township, Bucks County. PA 63 runs northwest to southeast for most of its length. The route heads through a mix of suburban and rural areas of northern Montgomery County as a two-lane road, passing through Harleysville, before coming to an interchange with I-476 in Kulpsville. From this point, PA 63 continues through predominantly suburban areas of eastern Montgomery County as a two- to four-lane road, passing through Lansdale, Maple Glen, Willow Grove, and Huntingdon Valley. Upon entering Northeast Philadelphia, the route follows Red Lion Road and U.S. Route 1 (US 1) before heading southeast on a freeway called Woodhaven Road to I-95.
Pennsylvania Route 232 (PA 232) is a 25.2-mile-long (40.6 km) state highway located in southeastern Pennsylvania. The southern terminus of the route is at U.S. Route 1 (US 1)/US 13 at the Oxford Circle in Philadelphia. The northern terminus is at PA 32 in the borough of New Hope, Bucks County, on the banks of the Delaware River. The route passes through the urban areas of Northeast Philadelphia as Oxford Avenue, serving the Lawncrest, Burholme, and Fox Chase neighborhoods. Upon entering Montgomery County, PA 232 becomes Huntingdon Pike and through suburban areas, serving the communities of Rockledge, Huntingdon Valley, and Bryn Athyn. The route passes through more suburban development in Bucks County as Second Street Pike, running through Southampton and Richboro. In Wrightstown Township, PA 232 enters rural areas and becomes Windy Bush Road as it heads north to New Hope.
Pennsylvania Route 532 is a 19.1-mile-long (30.7 km) state route located in the Philadelphia, Pennsylvania area. The route runs from an intersection with U.S. Route 1 in Northeast Philadelphia north to an intersection with PA 32 in Washington Crossing near the Washington Crossing Bridge over the Delaware River. The route passes through developed areas in Northeast Philadelphia before heading north through suburban Bucks County, serving Feasterville, Holland, and Newtown before coming to Washington Crossing.
Pennsylvania Route 73 (PA 73) is a 62.32-mile (100.29 km) long east–west state highway in southeastern Pennsylvania. It runs from PA 61 near Leesport southeast to the New Jersey state line on the Tacony–Palmyra Bridge over the Delaware River in Philadelphia, where the road continues south as New Jersey Route 73. The route passes through rural areas of Berks County, crossing U.S. Route 222 (US 222) in Maiden Creek before heading southeast through Oley and Boyertown. PA 73 continues into Montgomery County and intersects PA 100 in Gilbertsville and PA 29 in Schwenksville before it heads into the northwest suburbs of Philadelphia. The route passes through Skippack and intersects US 202 in Center Square, PA 309 in Springfield Township, and PA 611 near Jenkintown. PA 73 continues through Northeast Philadelphia on Cottman Avenue, crossing US 1 and US 13 before coming to an interchange with Interstate 95 (I-95) near the Tacony–Palmyra Bridge.
Pennsylvania Route 150 is a 41.1-mile-long (66.1 km) highway in Central Pennsylvania. Its southern terminus is at PA 26 in Dale Summit, Pennsylvania near State College, at the location of the Nittany Mall. Its northern terminus is at U.S. Route 220 in Avis.
Pennsylvania Route 50 is a 32.7-mile-long (52.6 km) state highway located in western Pennsylvania. The western terminus of the route is at PA 844 in the Independence Township community of Independence less than a mile from the West Virginia state line. The eastern terminus is at PA 60 in Crafton Heights. PA 50 was designated in 1961, replacing the portion of PA 28 between West Virginia and Pittsburgh.
Pennsylvania Route 74 is a 96.4-mile-long (155.1 km) north–south state highway located in central Pennsylvania. The southern terminus of the route is at the Mason–Dixon line southwest of Delta, where the road continues into Maryland as Maryland Route 165. The northern terminus is at PA 75 south of Port Royal.
Pennsylvania Route 272 is a 54.7-mile-long (88.0 km) highway in southeastern Pennsylvania, in the Lancaster area. The southern terminus of the route is at the Mason–Dixon line southeast of Nottingham, where the road continues into Maryland as Maryland Route 272. The northern terminus is at an interchange with U.S. Route 222 and PA 568 near Adamstown, where PA 568 continues east. The route heads from the Maryland border northwest through the southwestern corner of Chester County, intersecting US 1 in Nottingham. PA 272 continues west into Lancaster County and intersects US 222 in Wakefield, where it turns north and passes through Buck before widening into a divided highway as it comes to another junction with US 222 in Willow Street. Here, the route becomes unsigned and follows US 222 north through Lancaster along a one-way pair of city streets. North of Lancaster, US 222 splits at an interchange with US 30 and PA 272 becomes signed again, heading northeast parallel to the freeway alignment of US 222 and passing through Akron, Ephrata, and Adamstown. The route enters Berks County and comes to its northern terminus.
U.S. Route 1 (US 1) is a major north–south U.S. Route, extending from Key West, Florida, in the south to Fort Kent, Maine, at the Canada–United States border in the north. In the U.S. state of Pennsylvania, US 1 runs for 81 miles (130 km) from the Maryland state line near Nottingham northeast to the New Jersey state line at the Delaware River in Morrisville, through the southeastern portion of the state. The route runs southwest to northeast and serves as a major arterial road through the city of Philadelphia and for many of the suburbs in the Delaware Valley metropolitan area. South of Philadelphia, the road mostly follows the alignment of the Baltimore Pike. Within Philadelphia, it mostly follows Roosevelt Boulevard. North of Philadelphia, US 1 parallels the route of the Lincoln Highway. Several portions of US 1 in Pennsylvania are freeways, including from near the Maryland state line to Kennett Square, the bypass of Media, the concurrency with Interstate 76 and the Roosevelt Expressway in Philadelphia, and between Bensalem Township and the New Jersey state line.
Pennsylvania Route 452 is a state highway in Delaware County, Pennsylvania. The route runs from U.S. Route 13 in Marcus Hook north to PA 352 in Lima. The route runs through suburban areas, passing through Linwood and Aston Township. PA 452 intersects Interstate 95 (I-95) and US 322 in Upper Chichester Township and US 1 in Lima. PA 452 was first designated by 1928 between its current termini. A portion of the route in Aston Township was realigned by 1950.
Pennsylvania Route 403 is a north–south state route in Somerset, Cambria and Indiana counties of Pennsylvania. The southern terminus is at U.S. Route 30 (US 30) in the hamlet of Kantner in Quemahoning Township. The northern terminus is at US 119 near Marion Center.
U.S. Route 13 (US 13) is a United States Numbered Highway running from Fayetteville, North Carolina, north to Morrisville, Pennsylvania. The route runs for 49.359 miles (79.436 km) through the Delaware Valley in the U.S. state of Pennsylvania. The route enters the state from Delaware in Marcus Hook, Delaware County. It continues northeast through Delaware County, passing through the city of Chester before heading through suburban areas along Chester Pike to Darby. US 13 enters the city of Philadelphia on Baltimore Avenue and runs through West Philadelphia to University City, where it turns north along several city streets before heading east across the Schuylkill River along Girard Avenue. The route turns north and heads to North Philadelphia, where it runs northeast along Hunting Park Avenue. US 13 becomes concurrent with US 1 on Roosevelt Boulevard, continuing into Northeast Philadelphia. US 13 splits southeast on a one-way pair of streets before heading northeast out of the city on Frankford Avenue. The route continues into Bucks County as Bristol Pike, heading northeast to Bristol, where it becomes a divided highway. US 13 becomes a freeway in Tullytown and continues north to its terminus at US 1 in Falls Township, near Morrisville. US 13 roughly parallels Interstate 95 (I-95) through its course in Pennsylvania.
Pennsylvania Route 453 is a 43.8-mile-long (70.5 km) state highway located in Huntingdon, Blair, and Clearfield counties in Pennsylvania. The southern terminus is at U.S. Route 22 (US 22) in Water Street; the northern terminus is at PA 879 in Curwensville.
U.S. Route 202 is a US Highway running from New Castle, Delaware, northeast to Bangor, Maine. In the U.S. state of Pennsylvania, the route runs for 59 miles (95 km), from the Delaware state line in Bethel Township, Delaware County, to the New Hope–Lambertville Toll Bridge over the Delaware River in Solebury Township, where the route crosses into New Jersey. The highway runs through the western and northern suburbs of Philadelphia in the Delaware Valley metropolitan area, and serves as a toll-free bypass around the city, avoiding the busy traffic and congestion on Interstate 95 (I-95). It is signed north–south and follows a general southwest–northeast direction through the state.
Ridge Pike is a major historic road in the U.S. state of Pennsylvania that opened in 1706 that originally connected Wissahickon Creek to Perkiomen Creek. Inside Philadelphia, it is called Ridge Avenue. Going westward, it traverses many eastern Pennsylvania neighborhoods in Montgomery County including Conshohocken and beyond, connecting with Germantown Pike near Collegeville and continuing to Pottstown. In Montgomery County, Ridge Pike is called Main Street in the Norristown area and again in Collegeville and Trappe, and is called High Street in the Pottstown area.
Germantown Pike is a historic road in Pennsylvania that opened in 1687, running from Philadelphia northwest to Collegeville. The road is particularly notable for the "imposing mansions" that existed in the Germantown neighborhood in Philadelphia. The road was left in ruins after the British destroyed it in the Revolutionary War during the 1777 Battle of Germantown, and was not rebuilt until 1809. Portions of Germantown Pike were signed as U.S. Route 422 (US 422) before the latter was rerouted along a freeway alignment to King of Prussia.
US 1 in Baltimore, MD 
US 13 in Philadelphia, PA 
