Ent-cassa-12,15-diene synthase

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*ent*-cassa-12,15-diene synthase
ent-cassa-12,15-diene synthase
Identifiers
EC no.	4.2.3.28
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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Last updated August 27, 2023

ent-Cassa-12,15-diene synthase (EC 4.2.3.28, OsDTC1, OsKS7) is an enzyme with systematic name ent-copalyl-diphosphate diphosphate-lyase (ent-cassa-12,15-diene-forming).^[1] This enzyme catalyses the following chemical reaction

ent-copalyl diphosphate

\rightleftharpoons

ent-cassa-12,15-diene + diphosphate

This class I diterpene cyclase produces ent-cassa-12,15-diene, a precursor of the rice phytoalexins (-)-phytocassanes A-E.

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Ent-cassa-12,15-diene 11-hydroxylase (EC 1.14.14.112, Formerly EC 1.14.13.145, ent-cassadiene C11alpha-hydroxylase, CYP76M7) is an enzyme with systematic name ent-cassa-12,15-diene,NADPH:oxygen 11-oxidoreductase. This enzyme catalyses the following chemical reaction

Ent-copalyl-diphosphate diphosphate-lyase may refer to:

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ent-Pimara-9(11),15-diene synthase is an enzyme with systematic name ent-copalyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

Levopimaradiene synthase is an enzyme with systematic name (+)-copalyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

Stemar-13-ene synthase is an enzyme with systematic name 9α-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming). This enzyme catalyses the following chemical reaction

9alpha-copalyl-diphosphate diphosphate-lyase may refer to:

Stemod-13(17)-ene synthase is an enzyme with systematic name 9α-copalyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

syn-Pimara-7,15-diene synthase is an enzyme with systematic name 9α-copalyl-diphosphate diphosphate-lyase (9β-pimara-7,15-diene-forming). This enzyme catalyses the following chemical reaction

Aphidicolan-16β-ol synthase (EC 4.2.3.42, PbACS) is an enzyme with systematic name 9α-copalyl-diphosphate diphosphate-lyase (aphidicolan-16β-ol-forming). This enzyme catalyses the following chemical reaction

Isopimara-7,15-diene synthase is an enzyme with systematic name (+)-copalyl diphosphate-lyase (isopimara-7,15-diene-forming). This enzyme catalyses the following chemical reaction

Labdatriene synthase is an enzyme with systematic name 9α-copalyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

ent-Isokaurene synthase is an enzyme with systematic name ent-copalyl-diphosphate diphosphate-lyase . This enzyme catalyses the following chemical reaction

Syn-copalyl-diphosphate synthase is an enzyme with systematic name 9alpha-copalyl-diphosphate lyase (decyclizing). This enzyme catalyses the following chemical reaction

References

↑ Cho EM, Okada A, Kenmoku H, Otomo K, Toyomasu T, Mitsuhashi W, Sassa T, Yajima A, Yabuta G, Mori K, Oikawa H, Toshima H, Shibuya N, Nojiri H, Omori T, Nishiyama M, Yamane H (January 2004). "Molecular cloning and characterization of a cDNA encoding ent-cassa-12,15-diene synthase, a putative diterpenoid phytoalexin biosynthetic enzyme, from suspension-cultured rice cells treated with a chitin elicitor". The Plant Journal. 37 (1): 1–8. doi: 10.1046/j.1365-313x.2003.01926.x . PMID 14675427.

External links

Ent-cassa-12,15-diene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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[1] Cho EM, Okada A, Kenmoku H, Otomo K, Toyomasu T, Mitsuhashi W, Sassa T, Yajima A, Yabuta G, Mori K, Oikawa H, Toshima H, Shibuya N, Nojiri H, Omori T, Nishiyama M, Yamane H (January 2004). "Molecular cloning and characterization of a cDNA encoding ent-cassa-12,15-diene synthase, a putative diterpenoid phytoalexin biosynthetic enzyme, from suspension-cultured rice cells treated with a chitin elicitor". The Plant Journal. 37 (1): 1–8. doi: 10.1046/j.1365-313x.2003.01926.x . PMID 14675427.

[1]

v t e Carbon–oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase/3-Hydroxyacyl ACP dehydrase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase
4.2.2: Acting on polysaccharides	Hyaluronate lyase
4.2.3: Acting on phosphates	Threonine synthase
4.2.99: Other	Carboxymethyloxysuccinate lyase Hydroperoxide lyase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)