Fortrea

Last updated

Fortrea Holdings Inc.
Company type Public company
Industry Pharmaceutical industry
Founded1968 as Environmental Sciences Corporation
1996 as Covance
January 31, 2023;21 months ago (2023-01-31) as Fortrea
Headquarters Durham, North Carolina, U.S.; operations in over 90 countries
Key people
Services Contract research organization
Revenue
  • Increase2.svg US$3.109 billion (2023)
  • Decrease2.svg US$63 million (2023)
  • Decrease2.svg -US$3 million (2023)
Total assets
  • Increase2.svg US$4.357 billion (2023)
Total equity
  • Decrease2.svg US$1.738 billion (2023)
Number of employees
Approximately 18,000 (2023)
Website fortrea.com
Footnotes /references
[1] [2]

Fortrea Holdings Inc. is a contract research organization organized in Delaware and headquartered in Durham, North Carolina with operations in 90 countries. Its customers are primarily in the pharmaceutical, biotechnology, and medical device industries. [1]

Contents

Its primary business is handling all aspects of clinical trials including phase I through IV clinical trial management, clinical pharmacology, and post-approval services. It handles regulatory affairs, protocol design, operational planning, study and site start-up, patient recruitment, project management, monitoring, data management and biostatistics, pharmacovigilance, medical writing, and mobile clinical services. It focuses on oncology, central nervous system and neurodegenerative, rare diseases, and cell and gene therapies. In the five years ending in 2023, it conducted more than 5,850 clinical trials involving over 1 million subjects. It also conducted over 600 studies for medical device companies. [1]

The company is one of the largest participants in the international primate trade and has been criticized for its animal testing practices, most specifically animal testing on non-human primates.

The company traces its roots to Environmental Sciences Corporation, formed in 1968. It was known as Hazleton from 1972 to 1990, Corning Lab Services from 1990 to 1996, Covance from 1996 to 2021, and Labcorp Drug Development from 2021 to 2023.

History

1968–1999

In 1968, Environmental Sciences Corporation was established in Seattle, Washington, manufacturing equipment related to laboratory animals. [3] In 1972, it acquired and took the name of Hazleton Laboratories, a contract laboratory that conducted toxicology testing. [3] In 1977, Corning Inc. purchased a stake in Hazleton and in 1987, it acquired the remainder of the company for $115 million. [3] [4] By 1982, Hazleton was the largest independent biological testing company and life sciences laboratory in the U.S. and the largest laboratory equipment manufacturer worldwide. [3] The company carried out animal toxicology tests of drugs, cosmetics, pesticides, and industrial chemicals, and bred rhesus monkeys and beagles for its own labs, as well as for chemical and drug companies, hospitals, universities and government agencies. It offered chemical analysis of new compound products for various industries, tested chemicals for gene mutations, and carried out research with monoclonal antibodies. [3] It sold the equipment manufacturing unit in the mid-1980s. [3]

In 1989, Corning Glass Works acquired G.H. Besselaar Associates, which conducted clinical trials for drug approvals. [5] In 1990, Hazleton acquired Microtest, a molecular toxicology center in York, England. [3] Corning Glass Works changed its name to Corning, and folded Besselaar and Hazelton into a new subsidiary, Corning Lab Services. In 1991, Corning Lab Services acquired SciCor. [6]

In 1992, it acquired Philadelphia Association of Clinical Trials. In 1993, Hazleton, Besselaar, and SciCor were combined into Corning Pharmaceutical Services, then Corning Life Sciences. [3]

In 1995, Corning Pharmaceutical Services acquired National Packaging Systems, an Allentown, Pennsylvania-based clinical trial packaging company. [3]

In 1997, Corning completed the corporate spin-off of its laboratory testing business as Quest Diagnostics and its pharmaceutical services business as Covance. [7] [8]

In the fourth quarter of 1998, the company acquired GDXI, which undertakes the capture and interpretation of electrocardiograms, and Berkeley Antibody Company, which provides contract services in custom antibody production, applied immunology, and custom animal testing to support the medical device industry and preclinical evaluations, for a total of $26 million in cash. [9]

2000-present

In 2000, the company opened a central laboratory in Singapore, building on clinical-development services formed in Singapore in 1996. [10] [11] In 2013, it expanded the capacity of the laboratory by 50%. [12] [13] [14]

In March 2001, the company sold Covance Pharmaceutical Packaging Services to Fisher Scientific for $137.5 million. [15] [16] [17]

In August 2005, it acquired GFI Clinical Services, an 80-bed clinical pharmacology business, from West Pharmaceutical Services for $5.7 million. [18]

In April 2006, the company acquired eight early phase clinical pharmacology sites from Radiant Research for $65 million. [19] [20] [21]

In June 2006, it acquired Signet Laboratories, a provider of monoclonal antibodies used in the research of cancer, infectious disease, and neurodegenerative disease, for $8.95 million. [22]

In 2007, the company opened a laboratory in Shanghai, China. [23] In 2019, it opened a research and development center in Shanghai. [24]

In August 2008, the company acquired a campus in Greenfield, Indiana from Eli Lilly and Company and executed a 10-year service drug development service agreement with Lilly. [25] [26]

In December 2008, the company acquired a minority equity stake in Caprion Proteomics, a provider of proteomics-based services to the pharmaceutical industry. [27] [28] The company was acquired by Chicago Growth Partners in July 2012. [29]

In 2009, the company acquired the Gene Expression Laboratory from Merck & Co. and entered into a five-year, $145 million contract to provide Merck with genomic analysis services. [30] [31] [32]

In 2010, the company and Sanofi-Aventis created an outsourcing partnership, which, at the time was considered the largest between a contract research organization and a pharmaceutical company. Covance also acquired sites from Sanofi-Aventis in Porcheville, France and Alnwick, United Kingdom. [33] [34] [35]

In 2014, the company acquired Medaxial, a London-based value communication consultancy. [36]

In February 2015, Labcorp acquired Covance for $6.1 billion in cash and stock. [37] [38]

In 2016, the company entered into a strategic alliance with Global Specimen Solutions, in which the company offered GSS products GlobalCODE and snapTRACK to its clients. [39] In December 2017, Covance acquired the company. [40]

In September 2017, the company acquired Chiltern, a specialty contract research organization, for $1.2 billion in cash. [41] [42] [43]

In June 2018, the company acquired Sciformix Corporation, a scientific process outsourcing company focused on pharmacovigilance and regulatory issues for biopharmaceutical and medical devices clients. [44] [45] [46]

In August 2018, Covance Food Solutions was sold to Eurofins Scientific for $670 million. [47] [48] [49]

In June 2019, the company acquired the nonclinical contract research services business of Envigo (now Inotiv), which acquired the research products business of the company. [50] [51]

In the first quarter of 2019, the company spent $47 million to acquire MI Bioresearch, a provider of preclinical capabilities in cell and gene therapy and oncology testing, and Regulatory and Clinical Research Institute (RCRI), a device-focused contract research organization. [52] [53]

In October 2020, the company acquired GlobalCare, a mobile nursing and ambulant care company with operations in more than 65 countries, and snapIoT, a company that provides a digitized clinical platform that supports remote participation in clinical trials. [54]

In June 2021, the company changed its name to Labcorp Drug Development. [55]

In February 2023, the company was renamed Fortrea Holdings. [56] In July 2023, Labcorp completed the corporate spin-off of the company. [57]

In June 2024, the company sold its Endpoint Clinical and Fortrea Patient Access businesses to Arsenal Capital Partners. [58]

Controversies

Reston virus: monkeys with ebola virus brought to U.S.

In December 1989, several crab-eating macaques with the Zaire ebolavirus were imported from Mindanao in the Philippines to the company's facility in Reston, Virginia. [59] [60] The strain of the virus became known as the Reston virus. It was the first ebola virus that emerged outside of Africa and was also the first known natural infection of ebola virus in nonhuman primates. [61] The facility was abandoned and torn down and the variant turned out to be non-lethal to humans. [62] The incident was an inspiration for The Hot Zone , a book by Richard Preston published in 1994. [63]

In March 1996, two macaques that had been shipped to the company's facility in Alice, Texas, tested positive for the Ebola virus from a group of 100 obtained from the same supplier. The virus strain was the same non-lethal Reston virus as in the earlier incident. [63]

Animal welfare issues

Reports from investigative journalists

In 2003, a German investigative journalist sponsored by the British Union for the Abolition of Vivisection (BUAV) filmed 40 hours of undercover footage at the company's primate-testing facility in Münster. [64] Two films were produced, which were shown on German public television in December 2003. The footage showed animal keepers dancing with half-anaesthetized monkeys, making their heads move to the rhythm of the music. [64] It also showed rough treatment of the monkeys by the staff. The monkeys were seen living isolated in small wire cages with little or no natural light and no environmental enrichment, with high noise levels caused by staff shouting and playing the radio, and undergoing surgery with no post-operative care. In response, the company maintained that clips showing different technicians working in different buildings had been edited together, resulting in a sequence of events that did not take place. The company also said there was group housing and pair housing for some monkeys that was not shown. In the films, the treatment of the monkeys was criticized by Jane Goodall. The environment minister for North Rhine-Westphalia asked the public prosecutor to investigate, and said that if the allegations were borne out, the company would lose its licence to keep primates. [64] [65] The company gained an injunction against the video. [66]

From April 2004 to March 2005, an undercover technician, sponsored by People for the Ethical Treatment of Animals (PETA), filmed the treatment of monkeys in the company's lab in Vienna, Virginia. Incidents filmed included the punching of injured monkey, failure to give veterinary care and self-mutilation by monkeys because of "failure to provide psychological enrichment". [67] The United States Department of Agriculture and the Food and Drug Administration investigated the claims and company agreed to a settlement of $8,720 and to fix the infractions. [68] [69] In June 2005, the company filed a lawsuit in the United States against PETA and the investigator for fraud, breach of employee contract, and conspiracy. [70] PETA agreed to hand over all video footage and written notes to the company, and agreed to a ban on conducting any infiltration of the company for five years. [71] The company then dropped the lawsuit. [69] The company filed a parallel lawsuit in England in an attempt to stop PETA showing the tape; the British judge called the footage "highly disturbing", and ruled that there was a legitimate public interest in the material being shown. The case was settled with PETA allowed to continue to publish the video. [72]

Celebrity protests of business expansion

In 2006, Paul McCartney protested a proposed $175 million animal testing laboratory by the company in Chandler, Arizona. [73] However, the laboratory opened in 2009. [74]

Animal welfare citations by the United States Department of Agriculture

In June 2011, a report showed that improper housing conditions led to frostbite on the tails of many monkeys. [75]

In February 2012, the company was cited after a monkey died after being entangled by an enrichment device. [76]

In March 2012, the company was cited for housing a monkey in isolation for almost eight months. [77]

Deaths of lab monkeys due to hyperthermia

The company was fined $31,500 for four violations of the Animal Welfare Act of 1966 after 13 cynomolgus monkeys died from hyperthermia in overheated rooms in September and October 2014. In July 2014, the company had transported monkeys to the facility without providing water or proper care and ignoring signs of weakness and distress. The company said it would add electronic temperature monitoring and alerts. [78]

Broken bone injuries in monkeys

In November 2023, the company was fined $9,000 due to the injuries of six monkeys between 2018 and 2022, mostly broken bones due to poor handling. After the injuries, four monkeys were euthanized. [79]

Related Research Articles

<span class="mw-page-title-main">Huntingdon Life Sciences</span> Contract research organisation

Huntingdon Life Sciences (HLS) was a contract research organisation (CRO) organized in Maryland and headquartered in East Millstone, New Jersey. It was founded in 1951 in Cambridgeshire, England. It had two laboratories in the United Kingdom and one in the United States. With over 1,600 employees, it was the largest non-clinical CRO in Europe and the third-largest non-clinical CRO in the world. In September 2015, Huntingdon Life Sciences, Harlan Laboratories, GFA, NDA Analytics and LSR associates merged into Envigo.

<span class="mw-page-title-main">Roche</span> Swiss multinational healthcare company

F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational holding healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth-largest pharmaceutical company in the world by revenue and the leading provider of cancer treatments globally. In 2023, the company’s seat in Forbes Global 2000 was 76.

Sanofi S.A. is a French multinational pharmaceutical and healthcare company headquartered in Paris, France. The corporation was established in 1973 and merged with Synthélabo in 1999 to form Sanofi-Synthélabo. In 2004, Sanofi-Synthélabo merged with Aventis and renamed to Sanofi-Aventis, which were each the product of several previous mergers. It changed its name back to Sanofi in May 2011. The company is a component of the Euro Stoxx 50 stock market index. In 2023, the company’s seat in Forbes Global 2000 was 89.

<span class="mw-page-title-main">Alex Pacheco (activist)</span> American animal rights activist

Alexander Fernando Pacheco is an American animal rights activist. He is the founder of 600 Million Dogs, co-founder and former chairman of People for the Ethical Treatment of Animals (PETA) and a member of the advisory board of the Sea Shepherd Conservation Society.

Stop Huntingdon Animal Cruelty (SHAC) was an international animal rights campaign to close down Huntingdon Life Sciences (HLS), Europe's largest contract animal-testing laboratory. HLS tests medical and non-medical substances on around 75,000 animals every year, from rats to primates. It has been the subject of several major leaks or undercover investigations by activists and reporters since 1989.

Quest Diagnostics Incorporated is an American clinical laboratory. A Fortune 500 company, Quest operates in the United States, Puerto Rico, Mexico, and Brazil. Quest also maintains collaborative agreements with various hospitals and clinics across the globe.

Invitae Corp. is a biotechnology company that was created as a subsidiary of Genomic Health in 2010 and then spun-off in 2012.

In the life sciences, a contract research organization (CRO) is a company that provides support to the pharmaceutical, biotechnology, and medical device industries in the form of research services outsourced on a contract basis. A CRO may provide such services as biopharmaceutical development, biological assay development, commercialization, clinical development, clinical trials management, pharmacovigilance, outcomes research, and real world evidence.

<span class="mw-page-title-main">Charles River Laboratories</span> American biotechnology and pharmaceutical corporation

Charles River Laboratories International, Inc., is an American pharmaceutical company specializing in a variety of preclinical and clinical laboratory, gene therapy and cell therapy services for the pharmaceutical, medical device and biotechnology industries. It also supplies assorted biomedical products, outsourcing services, and animals for research and development in the pharmaceutical industry and offers support in the fields of basic research, drug discovery, safety and efficacy, clinical support, and manufacturing.

Sigma-Aldrich is an American chemical, life science, and biotechnology company owned by the multinational chemical conglomerate Merck Group

<span class="mw-page-title-main">Silver Spring monkeys</span> Macaques used in neuroplasticity research; subjects of an animal-cruelty court case

The Silver Spring monkeys were 17 wild-born macaque monkeys from the Philippines who were kept in the Institute for Behavioral Research in Silver Spring, Maryland. From 1981 until 1991, they became what one writer called the most famous lab animals in history, as a result of a battle between animal researchers, animal advocates, politicians, and the courts over whether to use them in research or release them to a sanctuary. Within the scientific community, the monkeys became known for their use in experiments into neuroplasticity—the ability of the adult primate brain to reorganize itself.

Parexel International is an American provider of biopharmaceutical services. It conducts clinical trials on behalf of its pharmaceutical clients to expedite the drug approval process. It is the second largest clinical research organization in the world and has helped develop approximately 95% of the 200 top-selling biopharmaceuticals on the market today. The company publishes the annual Parexel R&D Statistical Sourcebook and operates the Parexel-Academy.

<span class="mw-page-title-main">Genzyme</span> Company

Genzyme was an American biotechnology company based in Cambridge, Massachusetts. From its acquisition in 2011 to 2022 Genzyme operated as a fully owned subsidiary of Sanofi. In 2010, Genzyme was the world's third-largest biotechnology company, employing more than 11,000 people around the world. As a subsidiary of Sanofi, Genzyme had a presence in approximately 65 countries, including 17 manufacturing facilities and 9 genetic-testing laboratories. Its products were also sold in 90 countries. In 2007, Genzyme generated $3.8 billion in revenue with more than 25 products on the market. In 2006 and 2007, Genzyme was named one of Fortune magazine’s “100 Best Companies to Work for”. The company donated $83 million worth of products worldwide; in 2006, it made $11 million in cash donations. In 2005, Genzyme was awarded the National Medal of Technology, the highest level of honor awarded by the president of the United States to America's leading innovators. In February 2022, Sanofi's new corporate brand was unveiled and former entity "Sanofi Genzyme" got integrated into Sanofi.

<span class="mw-page-title-main">International primate trade</span> International trade in primates

The international trade in primates sees 32,000 wild non-human primates (NHPs) trapped and sold on the international market every year. They are sold mostly for use in animal testing, but also for food, for exhibition in zoos and circuses, and for private use as companion animals.

<span class="mw-page-title-main">Animal testing on non-human primates</span> Experimentation using other primate animals

Experiments involving non-human primates (NHPs) include toxicity testing for medical and non-medical substances; studies of infectious disease, such as HIV and hepatitis; neurological studies; behavior and cognition; reproduction; genetics; and xenotransplantation. Around 65,000 NHPs are used every year in the United States, and around 7,000 across the European Union. Most are purpose-bred, while some are caught in the wild.

Laboratory Corporation of America Holdings (Labcorp), headquartered in Burlington, North Carolina, provides laboratory services used for diagnosis and healthcare decisions. It operates one of the largest clinical laboratory networks in the world and has operations in over 100 countries; although its operations are primarily in the U.S.

<span class="mw-page-title-main">Santaris Pharma</span> Biopharmaceutical company founded in Denmark

Santaris Pharma A/S was a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. The company also had a branch in San Diego, California that opened in 2009. Created by a merger between Cureon and Pantheco, Santaris developed RNA-targeted medicines using a Locked Nucleic Acid (LNA) Drug Platform and Drug Development Engine.

<span class="mw-page-title-main">Merck & Co.</span> American multinational pharmaceutical company

Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey, and is named for Merck Group, founded in Germany in 1668, of which it was once the American arm. The company does business as Merck Sharp & Dohme or MSD outside the United States and Canada. It is one of the largest pharmaceutical companies in the world, generally ranking in the global top five by revenue.

<span class="mw-page-title-main">Ionis Pharmaceuticals</span> Biotechnology company

Ionis Pharmaceuticals, Inc. is a biotechnology company based in Carlsbad, California, that specializes in discovering and developing RNA-targeted therapeutics. The company has three commercially approved medicines: Spinraza (Nusinersen), Tegsedi (Inotersen), and Waylivra (Volanesorsen), and has four drugs in pivotal studies: tominersen for Huntington's disease, tofersen for SOD1-ALS, AKCEA-APO(a)-LRx for cardiovascular disease, and AKCEA-TTR-LRx for all forms of TTR amyloidosis.

<span class="mw-page-title-main">Inotiv</span> Contract research organization and laboratory animal sourcer

Inotiv, Inc. is a contract research organization organized in Indiana and headquartered in Lafayette, Indiana. The company operates two core business units: Discovery and Safety Assessment (DSA) and Research Models and Services (RMS). The CRS business unit offers drug development and environmental sciences services, including safety assessment, analytical, metabolism, CMC and regulatory consultancy for small molecule drug candidates, biotherapeutics, and biomedical devices. The RMS business unit provides research models, lab animal diets and bedding and support services.

References

  1. 1 2 3 "Fortrea Holdings Inc. Form 10-K for the Fiscal Year Ended December 31, 2023". U.S. Securities and Exchange Commission. March 13, 2024.
  2. ↑ "General Information Name Search". Delaware.
  3. 1 2 3 4 5 6 7 8 9 "Covance Inc". Encyclopedia.com .
  4. ↑ "COMPANY NEWS; Corning-Hazleton" . The New York Times . Reuters. January 3, 1987.
  5. ↑ "CORNING GLASS TO ACQUIRE G.H. BESSELAAR ASSOCIATES". The Journal of Commerce . December 26, 1988.
  6. ↑ "Briefs". The New York Times . March 30, 1991. Archived from the original on March 6, 2016.
  7. ↑ "Corning Incorporated Completes Spin-off of Quest Diagnostics and Covance to Shareholders" (Press release). Quest Diagnostics. January 2, 1997.
  8. ↑ "Corning to Spin Off 2 Subsidiaries to Shareholders" . The New York Times . Reuters. November 28, 1996. ISSN   0362-4331.
  9. ↑ "Covance Inc. FORM 10-K for the Fiscal Year Ended December 31, 1998". U.S. Securities and Exchange Commission. March 4, 1999.
  10. ↑ "Covance Inc. FORM 10-K for the Fiscal Year Ended December 31, 2000". U.S. Securities and Exchange Commission. March 13, 2001.
  11. ↑ "The opening of Covance (Asia) Pte Ltd's expanded central laboratory" (Press release). Ministry of Health. April 7, 2006.
  12. ↑ "Covance Expands Singapore Central Laboratory by 50 Percent to Meet Clients' Increased Asia Pacific Focus" (Press release). PR Newswire. April 16, 2013.
  13. ↑ Garde, Damian (April 16, 2013). "Covance Expands Singapore Central Laboratory by 50 Percent to Meet Clients' Increased Asia Pacific Focus". Fierce Biotech. MidOcean Partners.
  14. ↑ "CRO Covance Expands Laboratory In Singapore". Asian Scientist . April 22, 2013.
  15. ↑ "Fisher completes Covance deal". Manufacturing Chemist. March 2, 2001.
  16. ↑ "COMPANY NEWS; FISHER SCIENTIFIC TO BUY PACKAGING UNIT OF COVANCE" . The New York Times . Reuters. December 27, 2000.
  17. ↑ "Fisher Scientific to Acquire Packaging Unit of Covance" . The Wall Street Journal . December 26, 2000.
  18. ↑ "West Pharmaceutical Sells Evansville GFI Assets". WFIE . August 23, 2005.
  19. ↑ "Covance buys eight trial sites for $65M". Fierce Biotech. MidOcean Partners. April 20, 2006.
  20. ↑ "Covance to Increase Phase I/IIa Capacity With Acquisition of Eight Early Clinical Development Sites From Radiant Research" (Press release). PR Newswire. April 20, 2006.
  21. ↑ "Radiant Research Completes Sale Of Clinical Pharmacology Business Unit For Approximately $65 Million" (Press release). Business Wire. June 1, 2006.
  22. ↑ "Covance Inc. Expands Its Antibody Products And Services With The Acquisition Of Signet Laboratories, Inc. For $8.95 Million" (Press release). PR Newswire. June 1, 2006.
  23. ↑ "Covance Inc. Central Laboratory Receives CAP Accreditation in China" (Press release). PR Newswire. April 6, 2009.
  24. ↑ "Covance Unveils New R&D Center in Shanghai" (Press release). Labcorp. September 10, 2019.
  25. ↑ "Lilly Sells its Greenfield, Indiana, Operations to Covance; Expands Existing Collaboration Between the Two Companies" (Press release). Eli Lilly & Company. August 6, 2008.
  26. ↑ "Covance and Eli Lilly and Company Execute 10-Year, $1.6 Billion Services Contract; Covance to Acquire Lilly's Greenfield, Indian". Fierce Biotech. MidOcean Partners. August 6, 2008.
  27. ↑ "Covance Purchases Equity Stake in Caprion Proteomics". Fierce Biotech. MidOcean Partners. December 16, 2008.
  28. ↑ "Covance Purchases Equity Stake in Caprion Proteomics". Mary Ann Liebert . December 17, 2008.
  29. ↑ "Chicago Caprion Proteomics completes sale to Chicago Growth Partners". McCarthy Tétrault.
  30. ↑ Myers, Calisha (August 10, 2009). "Covance to Acquire Seattle-Based Gene Expression Laboratory from Merck & Co., Inc". Fierce Biotech. MidOcean Partners.
  31. ↑ "Covance Purchases Equity Stake in Caprion Proteomics". Fierce Biotech. MidOcean Partners. December 16, 2008.
  32. ↑ "Covance Takes Over Merck & Co.'s Gene-Expression Lab and Gains $145M Contract". Mary Ann Liebert . July 30, 2009.
  33. ↑ Jack, Andrew (October 1, 2010). "Sanofi-Aventis in $2.2bn deal with Covance". Financial Times .
  34. ↑ Carroll, John (September 30, 2010). "Sanofi ejects two R&D sites, forges $2.2B pact with Covance". Fierce Biotech. MidOcean Partners.
  35. ↑ "Sanofi-Aventis Sells Two CMC Sites to Covance for $25M in $1–2B Services Deal". Mary Ann Liebert . September 30, 2010.
  36. ↑ Garde, Damian (May 19, 2014). "Covance Acquires Medaxial". Fierce Biotech. MidOcean Partners.
  37. ↑ "LabCorp Completes Acquisition of Covance" (Press release). Labcorp. February 19, 2015.
  38. ↑ Covington, Owen (February 19, 2015). "Covance purchase a done deal for LabCorp" . American City Business Journals .
  39. ↑ "Global Specimen Solutions, Inc. Announces 5-Year Strategic Alliance with Covance" (Press release). PR Web. October 13, 2016.
  40. ↑ "LABORATORY CORPORATION OF AMERICA HOLDINGS FORM 10-K for the Fiscal Year Ended December 31, 2017". U.S. Securities and Exchange Commission. February 22, 2018.
  41. ↑ "LabCorp Completes Acquisition of Chiltern" (Press release). Labcorp. September 1, 2017.
  42. ↑ Adams, Ben (July 31, 2017). "LabCorp snaps up Chiltern in $1.2B cash buy". Fierce Biotech. MidOcean Partners.
  43. ↑ "LabCorp Acquires Chiltern, Evotec Buys Aptuit as CROs Consolidate Further". Mary Ann Liebert . July 31, 2017.
  44. ↑ "LabCorp Expands Drug Development Solutions with Acquisition of Sciformix" (Press release). Labcorp. June 11, 2018.
  45. ↑ Hale, Conor (June 11, 2018). "LabCorp acquires Sciformix to add postmarket services to Covance's portfolio". Fierce Biotech. MidOcean Partners.
  46. ↑ Seaman, Jessica (June 11, 2018). "LabCorp makes another acquisition to expand its drug development services" . American City Business Journals .
  47. ↑ Joyce, John (August 2, 2018). "LabCorp completes $670M sale of Covance Food Solutions" . American City Business Journals .
  48. ↑ "Eurofins Announces the Acquisition of Covance Food Solutions" (Press release). Eurofins Scientific. August 2, 2018.
  49. ↑ "Labcorp Enters into Definitive Agreement to Sell Covance Food Solutions to Eurofins for $670 Million" (Press release). Business Wire. April 30, 2018.
  50. ↑ "LabCorp and Envigo Complete Innovative Transactions" (Press release). Labcorp. June 3, 2019.
  51. ↑ Adams, Ben (April 25, 2019). "LabCorp spends $485M as its CRO unit snaps up Envigo's nonclinical business". Fierce Biotech. MidOcean Partners.
  52. ↑ "MI Bioresearch has been sold to Covance, a subsidiary of LabCorp". Lincoln International . 2019.
  53. ↑ Adams, Ben (January 21, 2020). "LabCorp's CRO unit Covance doubles down on cell, gene therapy offerings". Fierce Biotech. MidOcean Partners.
  54. ↑ "LabCorp Transforms the Clinical Trial Experience And Streamlines the Drug Development Process" (Press release). Business Wire. October 20, 2020.
  55. ↑ Cadman, Nola (June 8, 2021). "Covance will soon be Labcorp Drug Development". Pharmiweb.jobs.
  56. ↑ Keenan, Joseph (February 16, 2023). "Labcorp's spinoff CRO business gets a name—Fortrea". Fierce Biotech. MidOcean Partners.
  57. ↑ "Labcorp Completes Spin-off of Fortrea" (Press release). PR Newswire. July 3, 2023.
  58. ↑ "Fortrea Completes Divestiture of Endpoint Clinical and Patient Access Businesses to Arsenal Capital Partners" (Press release). Globe Newswire. June 4, 2024.
  59. ↑ "Deadly Virus Discovered in Laboratory Monkeys" . The New York Times . Associated Press. December 3, 1989.
  60. ↑ Cohn, D'Vera (December 1, 1989). "Deadly Ebola Virus Found In Va. Laboratory Monkey;Animals Sent to Reston From Philippines" . The Washington Post .
  61. ↑ Miranda, Mary Elizabeth G.; Miranda, Noel Lee J. (November 1, 2011). "Reston ebolavirus in Humans and Animals in the Philippines: A Review". The Journal of Infectious Diseases . 204.
  62. ↑ "25 years ago in Virginia, a very different Ebola outbreak". CBS News . Associated Press. August 10, 2014.
  63. 1 2 HART, LIANNE (April 23, 1996). "MEDICINE : Texas Ebola Scare Is Over, but Coast Isn't Completely Clear". Los Angeles Times .
  64. 1 2 3 Schiermeier, Quirin (January 1, 2004). "Primate lab faces closure threat over mistreatment charge". Nature . Archived from the original on September 6, 2008.
  65. ↑ Primate Abuse at Covance in Germany - Undercover TV. Alliance for Animals and the Environment. March 20, 2014 – via YouTube.
  66. ↑ Gardner, Eriq (January 20, 2014). "European Court Won't Lift Ban on Monkey Abuse Film". The Hollywood Reporter .
  67. ↑ "Animal-rights group alleges monkey abuse". United Press International . May 18, 2005.
  68. ↑ Sinha, Vandana (April 7, 2008). "Plan to lure animal testing firm Covance has PETA growling" . American City Business Journals .
  69. 1 2 Buske, Jennifer (August 3, 2008). "PETA Urges Withdrawal Of Support for Drug-Test Lab". The Washington Post .
  70. ↑ "Court report: Covance files suit vs. PETA; Scrushy says 'no plea bargain'". Bioworld. June 8, 2005.
  71. ↑ Murray, Iain; Osorio, Ivan (January 17, 2006). "PETA: Cruel and Unusual". Competitive Enterprise Institute .
  72. ↑ "Covance Drops Appeal Of High Court Judgment, Allowing PETA Europe To Show Video Of Monkey Abuse Inside Its Lab". People for the Ethical Treatment of Animals (Press release). July 26, 2005.
  73. ↑ "McCartney protests against animal testing lab". Today . Associated Press. March 8, 2006.
  74. ↑ "Covance officially opens Chandler lab". East Valley Tribune .
  75. ↑ "Inspection Report" (PDF). United States Department of Agriculture . June 9, 2011.
  76. ↑ "Inspection Report" (PDF). United States Department of Agriculture . February 14, 2012.
  77. ↑ "Inspection Report" (PDF). United States Department of Agriculture . March 2, 2012.
  78. ↑ "Texas research facility fined for deaths of primates". Associated Press. July 29, 2016.
  79. ↑ Wahlberg, David (November 13, 2023). "Labcorp fined after animal research violations in Madison" . Wisconsin State Journal .
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.