Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in their natural environments or habitats. Experimental research with animals is usually conducted in universities, medical schools, pharmaceutical companies, defense establishments, and commercial facilities that provide animal-testing services to the industry. The focus of animal testing varies on a continuum from pure research, focusing on developing fundamental knowledge of an organism, to applied research, which may focus on answering some questions of great practical importance, such as finding a cure for a disease. Examples of applied research include testing disease treatments, breeding, defense research, and toxicology, including cosmetics testing. In education, animal testing is sometimes a component of biology or psychology courses.
Vivisection is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure. The word is, more broadly, used as a pejorative catch-all term for experimentation on live animals by organizations opposed to animal experimentation, but the term is rarely used by practising scientists. Human vivisection, such as live organ harvesting, has been perpetrated as a form of torture.
In the animal rights movement, cruelty-free is a label for products or activities that do not harm or kill animals anywhere in the world. Products tested on animals or made from animals are not considered cruelty-free, since these tests are often painful and cause the suffering and death of millions of animals every year.
Frances Power Cobbe was an Anglo-Irish writer, philosopher, religious thinker, social reformer, anti-vivisection activist and leading women's suffrage campaigner. She founded a number of animal advocacy groups, including the National Anti-Vivisection Society (NAVS) in 1875 and the British Union for the Abolition of Vivisection (BUAV) in 1898, and was a member of the executive council of the London National Society for Women's Suffrage.
The Humane Research Trust (HRT) is a British medical research charity with the aim of spreading the practice of humane research. They work with scientists as well as students to further the commitment of non-animal based research.
Shamrock Farm was the United Kingdom's only non-human primate importation and quarantine centre, located in Small Dole, near Henfield in West Sussex. The centre, owned by Bausch and Lomb and run by Charles River Laboratories, Inc. for Shamrock (GB) Ltd, provided animals to various laboratories and universities for use in animal testing. It was Europe's largest supplier of primates to laboratories, and held up to 350 monkeys at a time.
Muriel Dowding, Baroness Dowding was an English humanitarian and animal rights activist known for championing anti-vivisection, vegetarianism and the improvement of animal welfare. Like her second husband Lord Dowding, 1st Baron Dowding she was a vegetarian, an anti-vivisectionist, spiritualist and theosophist. She coined the term cruelty-free and was a pioneer of the cruelty-free movement.
Walter Robert Hadwen was an English general practitioner, pharmaceutical chemist and writer. He was president of the British Union for the Abolition of Vivisection (BUAV) and an anti-vaccination campaigner, known for his denial of the germ theory of disease.
Cambridge University primate experiments came to public attention in 2002 after the publication that year of material from a ten-month undercover investigation in 1998 by the British Union for the Abolition of Vivisection (BUAV). The experiments were being conducted on marmosets, and included the removal of parts of their brains intended to simulate the symptoms of stroke or Parkinson's disease. Some of the research was theoretical, aimed at advancing knowledge of the brain, while some of it was applied.
Gillian Rose Langley is a British scientist and writer who specialises in alternatives to animal testing and animal rights. She was, from 1981 until 2009, the science director of the Dr Hadwen Trust for Humane Research, a medical research charity developing non-animal research techniques. She was an anti-vivisection member of the British government's Animal Procedures Committee for eight years, and has worked as a consultant on non-animal techniques for the European Commission, and for animal protection organizations in Europe and the United States. Between 2010 and 2016 she was a consultant for Humane Society International.
The National Anti-Vivisection Society (NAVS) is an international not-for-profit animal protection group, based in London, working to end animal testing, and focused on the replacement of animals in research with advanced, scientific techniques. Since 2006, the NAVS has operated its international campaigns under the working name Animal Defenders International (ADI), and the two groups now work together under the ADI name.
Experiments involving non-human primates (NHPs) include toxicity testing for medical and non-medical substances; studies of infectious disease, such as HIV and hepatitis; neurological studies; behavior and cognition; reproduction; genetics; and xenotransplantation. Around 65,000 NHPs are used every year in the United States, and around 7,000 across the European Union. Most are purpose-bred, while some are caught in the wild.
Nafovanny in Vietnam is the largest captive-breeding primate facility in the world, supplying long-tailed macaques to animal testing laboratories, including Huntingdon Life Sciences in the UK and Covance in Germany.
Women have played a central role in animal advocacy since the 19th century. The animal advocacy movement – embracing animal rights, animal welfare, and anti-vivisectionism – has been disproportionately initiated and led by women, particularly in the United Kingdom. Women are more likely to support animal rights than men. A 1996 study of adolescents by Linda Pifer suggested that factors that may partially explain this discrepancy include attitudes towards feminism and science, scientific literacy, and the presence of a greater emphasis on "nurturance or compassion" amongst women. Although vegetarianism does not necessarily imply animal advocacy, a 1992 market research study conducted by the Yankelovich research organization concluded that "of the 12.4 million people [in the US] who call themselves vegetarian, 68% are female, while only 32% are male".
The American Anti-Vivisection Society (AAVS) is a Jenkintown, Pennsylvania-based animal protectionism organization created with the goal of eliminating a number of different procedures done by medical and cosmetic groups in relation to animal cruelty in the United States. It seeks to help the betterment of animal life and human-animal interaction through legislation reform. It was the first anti-vivisection organization founded in the United States.
Beauty Without Cruelty (BWC) was founded as an educational charitable trust in England in 1959 by Muriel, the Lady Dowding (1908–1993), past president of the National Anti-Vivisection Society (NAVS) and wife of Lord Dowding (1882–1970), the former commander-in-chief of RAF Fighter Command during the Battle of Britain. It investigated and exposed the brutality inflicted on animals in the fur and cosmetic trade and led the way in the commercial production of synthetic alternatives to fur and cosmetics, without the use of animal ingredients and not tested on animals, pioneering the cruelty-free movement. The initial fundamental purpose of the charitable trust was to demonstrate that alternatives to cruelly derived clothing and cosmetics were easily obtainable and, if they did not exist, to get them on the market. BWC spread the concept that one could easily look beautiful, without inflicting cruelty and death upon any creature.
Rise for Animals is a national, registered 501(c)(3) nonprofit animal rights organization which aims to end nonhuman animal experimentation. It has been described as "one of the oldest and wealthiest anti-vivisection organizations in the United States".
The Anti-Vivisection Coalition (AVC) is a United Kingdom-based pressure group which campaigns against animal testing. The AVC are described as 'main driver' of the Stop Vivisection Initiative, a petition launched in November 2012 which attracted more than a million signatures. The Stop Vivisection Initiative called upon the European Union to ban animal testing. If the signatures are verified, "the initiative will be granted hearings at the European Commission and the European Parliament".
The European Coalition to End Animal Experiments (ECEAE) is a European umbrella organisation actively operating in favour of animal rights and in particularly, an abolishment of testing on animals. The ECEAE was created in 1990 as an umbrella association for national organisations working for the abolition of all animal experiments. The original aim was to reach a ban on the testing of cosmetics on animals. Later, other campaign objectives were added, including banning experiments on non-human primates, in the field of regulatory animal testing and animal tests for botulinum toxin, better known as botox.
Animal welfare and rights in Switzerland is about the treatment of and laws concerning non-human animals in Switzerland. Switzerland has high levels of animal welfare protection by international standards.
