People for the Ethical Treatment of Animals is an American animal rights nonprofit organization based in Norfolk, Virginia, and led by Ingrid Newkirk, its international president. PETA says that its entities have more than 9 million members globally.
Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in their natural environments or habitats. Experimental research with animals is usually conducted in universities, medical schools, pharmaceutical companies, defense establishments, and commercial facilities that provide animal-testing services to the industry. The focus of animal testing varies on a continuum from pure research, focusing on developing fundamental knowledge of an organism, to applied research, which may focus on answering some questions of great practical importance, such as finding a cure for a disease. Examples of applied research include testing disease treatments, breeding, defense research, and toxicology, including cosmetics testing. In education, animal testing is sometimes a component of biology or psychology courses. The practice is regulated to varying degrees in different countries.
A veterinarian (vet) is a medical professional who practices veterinary medicine. They manage a wide range of health conditions and injuries in non-human animals. Along with this, veterinarians also play a role in animal reproduction, health management, conservation, husbandry and breeding and preventive medicine like nutrition, vaccination and parasitic control as well as biosecurity and zoonotic disease surveillance and prevention.
Animal euthanasia is the act of killing an animal humanely, most commonly with injectable drugs. Reasons for euthanasia include incurable conditions or diseases, lack of resources to continue supporting the animal, or laboratory test procedures. Euthanasia methods are designed to cause minimal pain and distress. Euthanasia is distinct from animal slaughter and pest control.
Alexander Fernando Pacheco is an American animal rights activist. He is the founder of 600 Million Dogs, co-founder and former chairman of People for the Ethical Treatment of Animals (PETA) and a member of the advisory board of the Sea Shepherd Conservation Society.
Labcorp Drug Development is a contract research organization headquartered in Burlington, North Carolina, providing nonclinical, preclinical, clinical and commercialization services to pharmaceutical and biotechnology industries. Formerly called Covance, the company is part of Labcorp, which employs more than 70,000 people worldwide.
The Oregon National Primate Research Center (ONPRC) is one of seven federally funded National Primate Research Centers in the United States and has been affiliated with Oregon Health and Science University (OHSU) since 1998. The center is located on 200 acres (0.81 km2) of land in Hillsboro, Oregon. Originally known as the Oregon Regional Primate Research Center (ORPRC), it was the first of the original seven primate centers established by the National Institutes of Health (NIH). The research center is administered and funded by the National Center for Research Resources, receiving $11 million in federal grants annually.
In 1985, a raid took place at a laboratory belonging to the University of California, Riverside (UCR) that resulted in the removal of a monkey by the Animal Liberation Front (ALF). This monkey, called Britches, was a stump-tailed macaque who was born into a breeding colony at UCR. He was removed from his mother at birth, had his eyelids sewn shut, and had an electronic sonar device attached to his head—a Trisensor Aid, an experimental version of a blind travel aid, the Sonicguide—as part of a three-year sensory-deprivation study involving 24 infant monkeys. The experiments were designed to study the behavioral and neural development of monkeys reared with a sensory substitution device.
Institutional Animal Care and Use Committees (IACUCs) are centrally important in applying laws about animal research in the United States. Similar systems operate in other countries, but generally under different titles; for example, in Canada a typical title would be the University Animal Care Committee (UACC), while in the United Kingdom it would be the Animal Welfare and Ethical Review Body (AWERB).
The Silver Spring monkeys were 17 wild-born macaque monkeys from the Philippines who were kept in the Institute for Behavioral Research in Silver Spring, Maryland. From 1981 until 1991, they became what one writer called the most famous lab animals in history, as a result of a battle between animal researchers, animal advocates, politicians, and the courts over whether to use them in research or release them to a sanctuary. Within the scientific community, the monkeys became known for their use in experiments into neuroplasticity—the ability of the adult primate brain to reorganize itself.
Edward Taub is a behavioral neuroscientist on the faculty at the University of Alabama at Birmingham. He is best known for his involvement in the Silver Spring monkeys case, for making discoveries in the area of neuroplasticity, and developing constraint-induced movement therapy; a family of techniques which helps the rehabilitation of people who have developed learned non-use as a result of suffering neurological injuries from a stroke or other cause.
Experiments involving non-human primates (NHPs) include toxicity testing for medical and non-medical substances; studies of infectious disease, such as HIV and hepatitis; neurological studies; behavior and cognition; reproduction; genetics; and xenotransplantation. Around 65,000 NHPs are used every year in the United States, and around 7,000 across the European Union. Most are purpose-bred, while some are caught in the wild.
This timeline of Animal Liberation Front (ALF) actions describes the history, consequences and theory of direct action on behalf of animals by animal liberation activists using, or associated with the ALF.
Primate experiments at Columbia University came to public attention in October 2003, when CNN reported that a university veterinarian had approached its Institutional Animal Care and Use Committee about experiments being carried out there on baboons.
The Animal Liberation Front (ALF) is an international, leaderless, decentralized political and social resistance movement that advocates and engages in what it calls non-violent direct action in protest against incidents of animal cruelty. It originated in Britain in the 1970s from the Bands of Mercy. Participants state it is a modern-day Underground Railroad, removing animals from laboratories and farms, destroying facilities, arranging safe houses, veterinary care and operating sanctuaries where the animals subsequently live. Critics have labelled them as eco-terrorists.
Pain negatively affects the health and welfare of animals. "Pain" is defined by the International Association for the Study of Pain as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage." Only the animal experiencing the pain can know the pain's quality and intensity, and the degree of suffering. It is harder, if even possible, for an observer to know whether an emotional experience has occurred, especially if the sufferer cannot communicate. Therefore, this concept is often excluded in definitions of pain in animals, such as that provided by Zimmerman: "an aversive sensory experience caused by actual or potential injury that elicits protective motor and vegetative reactions, results in learned avoidance and may modify species-specific behaviour, including social behaviour." Nonhuman animals cannot report their feelings to language-using humans in the same manner as human communication, but observation of their behaviour provides a reasonable indication as to the extent of their pain. Just as with doctors and medics who sometimes share no common language with their patients, the indicators of pain can still be understood.
A shock detector, shock indicator, or impact monitor is a device which indicates whether a physical shock or impact has occurred. These usually have a binary output (go/no-go) and are sometimes called shock overload devices. Shock detectors can be used on shipments of fragile valuable items to indicate whether a potentially damaging drop or impact may have occurred. They are also used in sports helmets to help estimate if a dangerous impact may have occurred.
Envigo (en-VEE-go) is a privately held contract research organization and laboratory animal sourcer that provides live animals and related products and services to pharmaceutical and biotechnology industries, government, academia and other life science organizations engaged in animal testing. The company breeds and sells research animals – which are referred to in the industry as "research models"– including rodents, rabbits, beagles and non-human primates. Envigo is headquartered in Indianapolis, Indiana and employs more than 1,200 people at 30+ locations across North America, Europe and the Middle East.
The Washington National Primate Research Center (WaNPRC) is a federally-funded biomedical research facility located on the Seattle campus of the University of Washington. The WaNPRC is one of seven National Primate Research Centers established by the National Institutes of Health in the 1960s The Washington primate center opened in 1961 and as of 2020, housed over 900 primates. The center is affiliated with the University of Washington Schools of Medicine, Public Health, affiliated research centers and the University of Washington Medical Center. It employs over 150 scientists and staff.
The Southwest National Primate Research Center (SNPRC) is a federally funded biomedical research facility affiliated with the Texas Biomedical Research Institute. The SNPRC became the seventh National Primate Research Center in 1999.
