GDP-4-dehydro-6-deoxy-D-mannose reductase

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GDP-4-dehydro-6-deoxy-D-mannose reductase
Identifiers
EC no. 1.1.1.281
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In enzymology, a GDP-4-dehydro-6-deoxy-D-mannose reductase (EC 1.1.1.281) is an enzyme that catalyzes the chemical reaction

GDP-6-deoxy-D-mannose + NAD(P)+ GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+

The 3 substrates of this enzyme are GDP-6-deoxy-D-mannose, NAD+, and NADP+, whereas its 4 products are GDP-4-dehydro-6-deoxy-D-mannose, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming). Other names in common use include GDP-4-keto-6-deoxy-D-mannose reductase [ambiguous], GDP-6-deoxy-D-lyxo-4-hexulose reductase, and Rmd. This enzyme participates in fructose and mannose metabolism.

Related Research Articles

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<span class="mw-page-title-main">GDP-mannose 4,6-dehydratase</span>

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References


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