Glucarate dehydratase

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glucarate dehydratase
1ecq.jpg
glucarate dehydratase tetramer, E.Coli
Identifiers
EC no. 4.2.1.40
CAS no. 9059-02-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

The enzyme glucarate dehydratase (EC 4.2.1.40) catalyzes the chemical reaction

D-glucarate 5-dehydro-4-deoxy-D-glucarate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming). Other names in common use include D-glucarate dehydratase, and D-glucarate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1BQG, 1EC7, 1EC8, 1EC9, 1ECQ, 1JCT, and 1JDF.

Related Research Articles

The enzyme Glucosaminate ammonia-lyase (EC 4.3.1.9) catalyzes the chemical reaction

<span class="mw-page-title-main">2-dehydro-3-deoxyglucarate aldolase</span> Class of enzymes

The enzyme 2-dehydro-3-deoxyglucarate aldolase catalyzes the chemical reaction

The enzyme 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43) catalyzes the chemical reaction

The enzyme 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) catalyzes the chemical reaction

The enzyme altronate dehydratase (EC 4.2.1.7) catalyzes the chemical reaction

The enzyme arabinonate dehydratase (EC 4.2.1.5) catalyzes the chemical reaction

The enzyme CDP-glucose 4,6-dehydratase (EC 4.2.1.45) catalyzes the chemical reaction

The enzyme D-fuconate dehydratase (EC 4.2.1.67) catalyzes the chemical reaction.

The enzyme dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) catalyzes the chemical reaction

The enzyme galactarate dehydratase (EC 4.2.1.42) catalyzes the chemical reaction

The enzyme galactonate dehydratase (EC 4.2.1.6) catalyzes the chemical reaction

<span class="mw-page-title-main">GDP-mannose 4,6-dehydratase</span>

The enzyme GDP-mannose 4,6-dehydratase (EC 4.2.1.47) catalyzes the chemical reaction

The enzyme gluconate dehydratase (EC 4.2.1.39) catalyzes the chemical reaction

The enzyme L-arabinonate dehydratase (EC 4.2.1.25) catalyzes the chemical reaction

The enzyme L-fuconate dehydratase (EC 4.2.1.68) catalyzes the chemical reaction

The enzyme Lrhamnonate dehydratase (EC 4.2.1.90) catalyzes the chemical reaction

The enzyme mannonate dehydratase (EC 4.2.1.8) catalyzes the chemical reaction

<span class="mw-page-title-main">Phosphogluconate dehydratase</span>

The enzyme phosphogluconate dehydratase (EC 4.2.1.12) catalyzes the chemical reaction

The enzyme UDP-glucose 4,6-dehydratase (EC 4.2.1.76) catalyzes the chemical reaction

The enzyme xylonate dehydratase (EC 4.2.1.82) catalyzes the chemical reaction:

References