Leonotis nepetifolia, (also known as klip dagga, Christmas candlestick, or lion's ear[2]), is a species of plant in the genusLeonotis and the family Lamiaceae (mint), It is native to tropical Africa.[1] It can also be found growing abundantly in much of Latin America, Southeast Asia, the West Indies,[1] and the Southeastern United States.[3] It grows to a height of 3 metres (9ft 10in) and has whorls of striking lipped flowers, that are most commonly orange,[2] but can vary to red, white, and purple. It has drooping dark green, very soft serrated leaves that can grow up to 10 centimetres (4in) wide.[2]Sunbirds and ants are attracted to the flowers.[2] It has been found growing on roadsides, rubbish heaps or waste land.[2]
L. nepetifolia is considered an invasive plant in Australia, Florida, and Hawaii, though its tendency to grow in disturbed areas led researchers in Hawaii to conclude it's not likely to be an ecological threat.[1]
Varieties
Leonotis nepetifolia var. africana(P.Beauv.) J.K.Morton - Indian Subcontinent, much of Africa (light orange flowers)
Leonotis nepetifolia var. nepetifolia - much of Africa (dark solid orange flowers)
Leonotis nepetifolia var. alba - (albino/white flowers)
Related species
Leonotis nepetifolia (klip dagga) is related to L. leonurus (wild dagga or lion's tail.) The most noticeable difference between the two is the leaf shape. L. nepetifolia leaves are cordate with serrated edges, except the top pair which are lanceolate with serrated edges, as pictured in taxonomy box. The leaves are all lanceolate with serrated edges on L. leonurus.
Traditional medicine
Leonotis nepetifolia is known in Trinidad as shandilay and the leaves are brewed as a tea for fever, coughs, womb prolapse, malaria, and suggested to be beneficial to bone and lung health. The roots of L. nepetifolia are considered to be the botanical sources of granthiparna, an ayurvedic herb.[citation needed]
Phytochemicals and pharmacology
Leonotis nepetifolia and wild dagga contains several labdane diterpenes including Hydroxynepetaefolin, Nepetaefuran, Nepetaefolinol, Nepetaefolin, Leonotinin, Leonotin and Dubiin as well as bispirolabdane diterpenes like Leonepetaefolin A-E.[4][5][6]
Methanol based extracts of Leonotis nepetifolia has shown antidepressant-like effects in mice. Metabolic screening of the extract suggested nepetaefolin, methoxynepataefolin, and 7-O-β-glucoside luteolin are the main products.[8]
Nepetaefuran and leonotinin isolated from Leonotis nepetaefolia plant material demonstrated anti-inflammatory by suppressing NF-κB activation related to proinflammatory Cytokines.[9]
↑ Blount, John F.; Manchand, Percy S. (1 January 1980). "X-Ray structure determination of methoxynepetaefolin and nepetaefolinol, labdane diterpenoids from Leonotis nepetaefolia R.Br". Journal of the Chemical Society, Perkin Transactions 1: 264–268. doi:10.1039/P19800000264.
This page is based on this Wikipedia article Text is available under the CC BY-SA 4.0 license; additional terms may apply. Images, videos and audio are available under their respective licenses.