Macrofilaricide

Last updated

A macrofilaricide is a chemotherapeutic compound that is active against adult filarial nematodes. [1] Many nematodes are economically important parasites of human and animal.

Nematode phylum of animals with tubular digestive systems with openings at both ends

The nematodes or roundworms constitute the phylum Nematoda. They are a diverse animal phylum inhabiting a broad range of environments. Taxonomically, they are classified along with insects and other moulting animals in the clade Ecdysozoa, and unlike flatworms, have tubular digestive systems with openings at both ends.

Parasitism Interaction between two organisms living together in more or less intimate association in a relationship in which association is disadvantageous or destructive to one of the organisms

In evolutionary biology, parasitism is a relationship between species, where one organism, the parasite, lives on or in another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson has characterised parasites as "predators that eat prey in units of less than one". Parasites include protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes. There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism, trophically transmitted parasitism, vector-transmitted parasitism, parasitoidism, and micropredation.

Related Research Articles

<i>Caenorhabditis elegans</i> free-living species of nematode

Caenorhabditis elegans is a free-living, transparent nematode, about 1 mm in length, that lives in temperate soil environments. It is the type species of its genus. The name is a blend of the Greek caeno- (recent), rhabditis (rod-like) and Latin elegans (elegant). In 1900, Maupas initially named it Rhabditides elegans, Osche placed it in the subgenus Caenorhabditis in 1952, and in 1955, Dougherty raised Caenorhabditis to the status of genus.

Northern root-knot nematode is a species of vegetable pathogens which produces tiny galls on around 550 crop and weed species. They invade root tissue after birth. Females are able to lay up to 1,000 eggs at a time in a large egg mass. By surviving harsh winters, they can survive in cold climates.

Enoplea class of roundworms

Enoplea (enopleans) is a class, which with the classes Secernentea and Chromadorea make up the phylum Nematoda in current taxonomy. The Enoplea are considered to be a more ancestral group than the Chromadorea, and researchers have referred to its members as the "ancestrally diverged nematodes", compared to the "more recently diverged nematodes" of Chromadorea.

Root-knot nematode genus of worms

Root-knot nematodes are plant-parasitic nematodes from the genus Meloidogyne. They exist in soil in areas with hot climates or short winters. About 2000 plants worldwide are susceptible to infection by root-knot nematodes and they cause approximately 5% of global crop loss. Root-knot nematode larvae infect plant roots, causing the development of root-knot galls that drain the plant's photosynthate and nutrients. Infection of young plants may be lethal, while infection of mature plants causes decreased yield.

Mustard plant plants used for mustard

Mustard plant is a plant species in the genera Brassica and Sinapis in the family Brassicaceae. Mustard seed is used as a spice. Grinding and mixing the seeds with water, vinegar, or other liquids creates the yellow condiment known as prepared mustard. The seeds can also be pressed to make mustard oil, and the edible leaves can be eaten as mustard greens.

<i>Meloidogyne incognita</i> species of worm

Meloidogyne incognita is a species of nematodes (roundworms) in the family Heteroderidae. It is commonly called the "southern root-knot nematode" or the "cotton root-knot nematode". This parasitic roundworm has worldwide distribution and numerous hosts. It is an important plant parasite classified in parasitology as a root-knot nematode, as it prefers to attack the root of its host plant.

Major sperm protein

The major sperm protein (MSP) is a nematode specific small protein of 126 amino acids with a molecular weight of 14 kDa. It is the key player in the motility machinery of nematodes that propels the crawling movement/motility of nematode sperm. It is the most abundant protein present in nematode sperm, comprising 15% of the total protein and more than 40% of the soluble protein. MSP is exclusively synthesized in spermatocytes of the nematodes. The MSP has two main functions in the reproduction of the helminthes: i) as cytosolic component it is responsible for the crawling movement of the mature sperm, and ii) once released, it acts as hormone on the female germ cells, where it triggers oocyte maturation and stimulates the oviduct wall to contract to bring the oocytes into position for fertilization. MSP has first been identified in Caenorhabditis elegans.

The Chromadorea are a class of the roundworm phylum, Nematoda. They contain a single subclass (Chromadoria) and several orders. With such a redundant arrangement, the Chromadoria are liable to be split up if the orders are found to form several clades, or abandoned if they are found to constitute a single radiation.

Carnivorous fungus

Carnivorous fungi or predaceous fungi are fungi that derive some or most of their nutrients from trapping and eating microscopic or other minute animals. More than 200 species have been described, belonging to the phyla Ascomycota, Mucoromycotina, and Basidiomycota. They usually live in soil and many species trap or stun nematodes, while others attack amoebae or collembola.

<i>Pratylenchus penetrans</i> species of worm

Pratylenchus penetrans is a species of nematode in the genus Pratylenchus, the lesion nematodes. It occurs in temperate regions worldwide, regions between the subtropics and the polar circles. It is an animal that inhabits the roots of a wide variety of plants and results in necrotic lesions on the roots. Symptoms of P. penetrans make it hard to distinguish from other plant pathogens; only an assay of soil can conclusively diagnose a nematode problem in the field. P. penetrans is physically very similar to other nematode species, but is characterized by its highly distinctive mouthpiece. P. penetrans uses its highly modified mouth organs to rupture the outer surface of subterranean plant root structures. It will then enter into the root interior and feed on the plant tissue inside. P. penetrans is considered to be a crop parasite and farmers will often treat their soil with various pesticides in an attempt to eliminate the damage caused by an infestation. In doing this, farmers will also eliminate many of the beneficial soil fauna, which will lead to an overall degradation of soil quality in the future. Alternative, more environmentally sustainable methods to control P. penetrans populations may be possible in certain regions.

Pratylenchus vulnus is a species of plant pathogenic nematodes infecting Persian walnut.

Xiphinema diversicaudatum is an amphimitic ectoparasitic nematode species. This species has a characteristically long stylet capable of penetrating into a host’s vascular tissue. They have a wide host range with some of the extensively studied ones being strawberry, hops and raspberry, due to their economic importance. The direct root damage caused through penetration near the root tip and formation of galls is a secondary concern when compared with the damage caused by vectoring the arabis mosaic virus. The virus attaches to the interior cuticle lining and can be transferred from infected to uninfected root tissue as the nematode feeds and sheds. Management of this particular nematode relies on nematicides such as 1,3-Dichloropropene (Telone) at 40 gpa.or methyl bromide at 1000 lb/ac to control to 28 in deep.

Nematology scientific discipline concerned with the study of nematodes, also called roundworms

Nematology is the scientific discipline concerned with the study of nematodes, or roundworms. Although nematological investigation dates back to the days of Aristotle or even earlier, nematology as an independent discipline has its recognizable beginnings in the mid to late 19th century.

<i>Pratylenchus</i> genus of worms

Pratylenchus is a genus of nematodes known commonly as lesion nematodes. They are parasitic on plants and are responsible for root lesion disease on many taxa of host plants in temperate regions around the world. Lesion nematodes are migratory endoparasites that feed and reproduce in the root and move around, unlike the cyst or root-knot nematodes, which may stay in one place. They usually only feed on the cortex of the root. Species are distinguished primarily by the morphology of the stylets.

Diplogasterida order of worms

Diplogasterida was an order of nematodes. It was sometimes placed in a monotypic subclass Diplogasteria, but molecular phylogenetic evidence has shown it to be embedded in the family Rhabditidae. The confusion of having a hierarchical nesting of groups that were formerly mutually exclusive has led to a profusion of names. Although completely revised taxonomy of nematodes that builds on recent classification systems as well as recent phylogenetic evidence is still necessary, most contemporary taxonomic studies now treat all groups listed under "Diplogasterina" below as a single family, Diplogastridae.

Tylenchorhynchus is a genus of nematodes including many species of plant parasites. The classification of stunt nematodes - those including the genus Tylenchorhynchus - is unstable; many newly discovered species within this genus are reconsidered to be actually subspecies. Stunt nematodes such as Tylenchorhynchus and the closely related genera, Anguillulina and Merlinia, include more than 250 known species. Members of these genera possess similar anatomy and may be easily mistaken for one another. Some debate has led to the classification of single species under different names in two distinct genera.

Nematode infection Human disease

A nematode infection is a type of helminthiasis caused by organisms in the nematode phylum.

The red ring disease of coconuts and African oil palms is caused by the nematode Bursaphelenchus cocophilus. It is also identified in literature with an alternative scientific name Rhadinaphelenchus cocophilus. The common name, the red ring nematode, is derived from its distinguishing symptom.

Legerella is a genus of parasitic alveolates of the phylum Apicomplexa. Species in this genus that usually infect the malpighian tubules of invertebrates.

References