Ciclobendazole

Last updated
Ciclobendazole
Ciclobendazole.svg
Clinical data
ATC code
Identifiers
  • Methyl N-[6-(cyclopropanecarbonyl)-1H-benzimidazol-2-yl]carbamate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.046.018 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C13H13N3O3
Molar mass 259.265 g·mol−1
3D model (JSmol)
  • COC(=O)Nc3nc2ccc(C(=O)C1CC1)cc2[nH]3
  • InChI=1S/C13H13N3O3/c1-19-13(18)16-12-14-9-5-4-8(6-10(9)15-12)11(17)7-2-3-7/h4-7H,2-3H2,1H3,(H2,14,15,16,18) X mark.svgN
  • Key:OXLKOMYHDYVIDM-UHFFFAOYSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Ciclobendazole is an anthelmintic, that is a pharmaceutical drug against parasitic worms. It underwent a clinical trial in the 1970s, where it was found to be as effective as mebendazole in the treatment of hookworm infection and ascariasis, but significantly less effective in the treatment of trichuriasis. [1]

It is not known to be marketed anywhere in the world. [2]

References

  1. Guggenmoos R, Akhtaruzzaman KM, Rosenkaimer F, Gaus W, Bienzle U, Dietrich M (December 1978). "Comparative trial on the therapeutic effectiveness of the new anthelmintic drug: ciclobendazole". Tropenmedizin und Parasitologie. 29 (4): 423–6. PMID   369076.
  2. "Ciclobendazole search results". Drugs.com. Retrieved 2021-03-31.