Nitroscanate

Last updated
Nitroscanate
Nitroscanate.png
Nitroscanate-3D-spacefill.png
Clinical data
Trade names Lopatol
AHFS/Drugs.com International Drug Names
ATCvet code
Identifiers
  • 1-(4-Isothiocyanatophenoxy)-4-nitrobenzene
CAS Number
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.039.433 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C13H8N2O3S
Molar mass 272.28 g·mol−1
3D model (JSmol)
  • C1=CC(=CC=C1N=C=S)OC2=CC=C(C=C2)[N+](=O)[O-]
  • InChI=1S/C13H8N2O3S/c16-15(17)11-3-7-13(8-4-11)18-12-5-1-10(2-6-12)14-9-19/h1-8H
  • Key:SVMGVZLUIWGYPH-UHFFFAOYSA-N
   (verify)

Nitroscanate (trade name Lopatol) is an anthelmintic drug used in veterinary medicine to treat Toxocara canis , Toxascaris leonina , Ancylostoma caninum , Uncinaria stenocephala , Taenia , and Dipylidium caninum (roundworms, hookworms and tapeworms). [1] [2]

Related Research Articles

Veterinary parasitology is a branch of veterinary medicine that deals with the study of morphology, life-cycle, pathogenesis, diagnosis, treatment, and control of eukaryotic invertebrates of the kingdom Animalia and the taxon Protozoa that depend upon other invertebrates and higher vertebrates for their propagation, nutrition, and metabolism without necessarily causing the death of their hosts. Modern parasitology focuses on responses of animal hosts to parasitic invasion. Parasites of domestic animals,, as well as wildlife animals are considered. Data obtained from parasitological research in animals helps in veterinary practice and improves animal breeding. The major goal of veterinary parasitology is to protect animals and improve their health, but because a number of animal parasites are transmitted to humans, veterinary parasitology is also important for public health.

<span class="mw-page-title-main">Cyclophyllidea</span> Order of flatworms

Tapeworms of the order Cyclophyllidea are the most important cestode parasites of humans and domesticated animals. All have multiple proglottid "segments", and all have four suckers on their scolices (heads), though some may have other structures, as well. Proglottids of this order have genital openings on one side, and a compact yolk gland or vitellarium posterior to the ovary.

<i>Dipylidium caninum</i> Species of flatworm

Dipylidium caninum, also called the flea tapeworm, double-pored tapeworm, or cucumber tapeworm is a cyclophyllid cestode that infects organisms afflicted with fleas and canine chewing lice, including dogs, cats, and sometimes human pet-owners, especially children.

<i>Ancylostoma</i> Genus of roundworms

Ancylostoma is a genus of nematodes that includes some species of hookworms.

<i>Neospora caninum</i> Species of Conoidasida in the apicomplex phylum

Neospora caninum is a coccidian parasite that was identified as a species in 1988. Prior to this, it was misclassified as Toxoplasma gondii due to structural similarities. The genome sequence of Neospora caninum has been determined by the Wellcome Trust Sanger Institute and the University of Liverpool. Neospora caninum is an important cause of spontaneous abortion in infected livestock.

<i>Neospora</i> Genus of single-celled organisms

Neospora is a single celled parasite of livestock and companion animals. It was not discovered until 1984 in Norway, where it was found in dogs. Neosporosis, the disease that affects cattle and companion animals, has a worldwide distribution. Neosporosis causes abortions in cattle and paralysis in companion animals. It is highly transmissible and some herds can have up to a 90% prevalence. Up to 33% of pregnancies can result in aborted fetuses on one dairy farm. In many countries this organism is the main cause of abortion in cattle. Neosporosis is now considered as a major cause of abortion in cattle worldwide. Many reliable diagnostic tests are commercially available. Neospora caninum does not appear to be infectious to humans. In dogs, Neospora caninum can cause neurological signs, especially in congenitally infected puppies, where it can form cysts in the central nervous system.

<span class="mw-page-title-main">Fenbendazole</span> Chemical compound

Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia, pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits, most reptiles, freshwater shrimp tanks as planaria and hydra treatments, as well as seals.

<span class="mw-page-title-main">Strongylida</span> Suborder of roundworms

The Strongylida suborder includes many of the important nematodes found in the gastrointestinal tracts of ruminants, horses, and swine, as well as the lungworms of ruminants and the hookworms of dogs and cats.

Nicarbazin is a coccidiostat used on meat chickens. It is also used as a contraceptive for population control of Canada geese and feral pigeons.

<i>Ancylostoma braziliense</i> Species of worm

Ancylostoma braziliense is a species of hookworm belonging to the genus Ancylostoma. It is an intestinal parasite of domestic cats and dogs. Severe infection is often fatal to these pets, especially in puppies and kittens. The infection is particularly endemic in the southern United States. It is most often confused with the zoonotic hookworm species Ancylostoma ceylanicum because of their uncanny resemblance.

<i>Ancylostoma caninum</i> Species of roundworm

Ancylostoma caninum is a species of nematode known as a hookworm, which principally infects the small intestine of dogs. The result of A. caninum infection ranges from asymptomatic cases to death of the dog; better nourishment, increasing age, prior A. caninum exposure, or vaccination are all linked to improved survival. Other hosts include carnivores such as wolves, foxes, and cats, with a small number of cases having been reported in humans.

Ancylostoma tubaeforme is a hookworm that infects cats worldwide. Infection can occur through penetration of the skin, ingestion of infected hosts, such as birds, or by directly consuming the organism. Ancylostoma tubaeforme along with Ancylostoma braziliense are the two most common hookworms to infect cats, causing anemia and compromising the immune system.

Nematode dermatitis is a cutaneous condition characterized by widespread folliculitis caused by Ancylostoma caninum.

<span class="mw-page-title-main">Epsiprantel</span> Chemical compound

Epsiprantel is a veterinary drug which is used as an anthelmintic against tapeworms such as Echinococcus granulosus.

The term cat tapeworm may refer to:

The term feline tapeworm may refer to:

<span class="mw-page-title-main">Hookworm</span> Intestinal, blood-feeding, parasitic roundworms that cause types of infection known as helminthiases

Hookworms are intestinal, blood-feeding, parasitic roundworms that cause types of infection known as helminthiases. Hookworm infection is found in many parts of the world, and is common in areas with poor access to adequate water, sanitation, and hygiene. In humans, infections are caused by two main species of roundworm, belonging to the genera Ancylostoma and Necator. In other animals the main parasites are species of Ancylostoma. Hookworm is closely associated with poverty because it is most often found in impoverished areas, and its symptoms promote poverty through the educational and health effects it has on children. It is the leading cause of anemia and undernutrition in developing countries, while being one of the most commonly occurring diseases among poor people. Hookworm thrives in areas where rainfall is sufficient and keeps the soil from drying out, and where temperatures are higher, making rural, coastal areas prime conditions for the parasite to breed.

"Chryseobacterium nematophagum" is a Gram-negative, aerobic and rod-shaped bacteria in the genus Chryseobacterium, which was first isolated from Caenorhabditis briggsae nematodes in rotting apples in France. It exhibits gliding motility. After ingestion by a nematode, they attack it from within, breaking down its extracellular matrices and killing it. In laboratory tests C. nematophagum infected and killed a wide variety of nematodes, including the model organism Caenorhabditis elegans, and the vertebrate parasites Ancylostoma caninum, Cooperia curtecei, Cooperia oncophera, Haemonchus contortus, Nippostrongylus brasiliensis, Ostertagia ostertagi, Parastrongyloides trichosura and Trichostrongylus vitrinus.

Imidacloprid/moxidectin, sold under the brand names Advantage Multi for Dogs and Advantage Multi for Cats among others, is a medicine for dogs and cats to treat heartworm, fleas, sarcoptic mange, intestinal parasites and ear mites.

Joyeuxiella pasquale is a species of flatworm, belonging to the family Dipylidiidae. The species uses coprophagous beetles and reptiles as transportation hosts with dogs, cats, and other wild carnivores being their final carrier for reproduction.

References

  1. "Lopatol (package insert)". Elanco. Retrieved 29 October 2020.
  2. Craig TM, Mercer SH, Wade CG, Lynn RC (April 1991). "Efficacy of nitroscanate against naturally acquired infection with Ancylostoma caninum, Dipylidium caninum, and Trichuris vulpis in dogs". American Journal of Veterinary Research. 52 (4): 574–5. PMID   2053726.