Miltiradiene synthase

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Miltiradiene synthase
Identifiers
EC no. 4.2.3.131
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Miltiradiene synthase (EC 4.2.3.131, SmMDS, SmiKSL) is an enzyme with systematic name (+)-copaly-diphosphate diphosphate-lyase (cyclizing, miltiradiene-forming). [1] [2] This enzyme catalyses the following chemical reaction

(+)-copalyl diphosphate miltiradiene + diphosphate

This enzyme is isolated from the plant Selaginella moellendorffii .

Related Research Articles

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<span class="mw-page-title-main">Bornyl diphosphate synthase</span>

In enzymology, bornyl diphosphate synthase (BPPS) (EC 5.5.1.8) is an enzyme that catalyzes the chemical reaction

In enzymology, an ent-copalyl diphosphate synthase is an enzyme that catalyzes the chemical reaction:

The enzyme abieta-7,13-diene synthase catalyzes the chemical reaction

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<span class="mw-page-title-main">Chlorophyll synthase</span> Class of enzymes

In enzymology, chlorophyll synthase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">GGPS1</span> Mammalian protein found in Homo sapiens

Geranylgeranyl pyrophosphate synthase is an enzyme that in humans is encoded by the GGPS1 gene.

Geranyl diphosphate 2-C-methyltransferase is an enzyme with systematic name S-adenosyl-L-methionine:geranyl-diphosphate 2-C-methyltransferase. This enzyme catalyses the following chemical reaction

Hexaprenyl diphosphate synthase is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate transferase . This enzyme catalyses the following chemical reaction

Hexaprenyl-diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase . This enzyme catalyses the following chemical reaction

All-trans-nonaprenyl-diphosphate synthase is an enzyme with systematic name geranyl-diphosphate:isopentenyl-diphosphate transtransferase . This enzyme catalyses the following chemical reaction

Ditrans,polycis-polyprenyl diphosphate synthase is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase . This enzyme catalyses the following chemical reaction

(13E)-labda-7,13-dien-15-ol synthase (EC 3.1.7.10, labda-7,13E-dien-15-ol synthase) is an enzyme with systematic name geranylgeranyl-diphosphate diphosphohydrolase [(13E)-labda-7,13-dien-15-ol-forming]. It catalyses the reaction

syn-Pimara-7,15-diene synthase is an enzyme with systematic name 9α-copalyl-diphosphate diphosphate-lyase (9β-pimara-7,15-diene-forming). This enzyme catalyses the following chemical reaction

Terpentetriene synthase is an enzyme with systematic name terpentedienyl-diphosphate diphosphate-lyase (terpentetriene-forming). This enzyme catalyses the following chemical reaction

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2-methylisoborneol synthase (EC 4.2.3.118, sco7700, 2-MIB cyclase, MIB synthase, MIBS) is an enzyme with systematic name (E)-2-methylgeranyl-diphosphate diphosphate-lyase (cyclizing, 2-methylisoborneol-forming). This enzyme catalyses the following chemical reaction

(E)-2-epi-β-Caryophyllene synthase (EC 4.2.3.137, (E)-2-epi-β-caryophyllene synthase, SmMTPSL26) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (E)-2-epi-β-caryophyllene-forming). This enzyme catalyses the following chemical reaction

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References

  1. ↑ Gao W, Hillwig ML, Huang L, Cui G, Wang X, Kong J, Yang B, Peters RJ (November 2009). "A functional genomics approach to tanshinone biosynthesis provides stereochemical insights". Organic Letters. 11 (22): 5170–3. doi:10.1021/ol902051v. PMC   2776380 . PMID   19905026.
  2. ↑ Sugai Y, Ueno Y, Hayashi K, Oogami S, Toyomasu T, Matsumoto S, Natsume M, Nozaki H, Kawaide H (December 2011). "Enzymatic (13)C labeling and multidimensional NMR analysis of miltiradiene synthesized by bifunctional diterpene cyclase in Selaginella moellendorffii". The Journal of Biological Chemistry. 286 (50): 42840–7. doi: 10.1074/jbc.m111.302703 . PMC   3234827 . PMID   22027823.
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