Mucuna pruriens

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Mucuna pruriens
Mucuna pruriens flower.jpg
Mucuna pruriens inflorescence
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Fabales
Family: Fabaceae
Subfamily: Faboideae
Genus: Mucuna
Species:
M. pruriens
Binomial name
Mucuna pruriens
(L.) DC.
Synonyms [1]
  • Carpogon capitatusRoxb.
  • Carpogon niveusRoxb.
  • Carpopogon capitatusRoxb.
  • Carpopogon niveumRoxb.
  • Carpopogon pruriens(L.) Roxb.
  • Dolichos pruriensL.
  • Macranthus cochinchinensisLour.
  • Marcanthus cochinchinenseLour.
  • Mucuna aterrima(Piper & Tracy) Holland
  • Mucuna atrocarpaF.P.Metcalf
  • Mucuna axillarisBaker
  • Mucuna bernierianaBaill.
  • Mucuna capitataWight & Arn.
  • Mucuna cochinchinense(Lour.) A.Chev.
  • Mucuna cochinchinensis(Lour.) A.Chev.
  • Mucuna deeringiana(Bort) Merr.
  • Mucuna esquiroliiH. Lév.
  • Mucuna esquiroliiH.Lev.
  • Mucuna hassjoo(Piper & Tracy) Mansf.
  • Mucuna hirsutaWight & Arn.
  • Mucuna luzoniensisMerr.
  • Mucuna lyoniiMerr.
  • Mucuna martiniiH.Lev. & Vaniot
  • Mucuna minimaHaines
  • Mucuna nivea(Roxb.) DC.
  • Mucuna nivea(Roxb.) Wight & Arn.
  • Mucuna prurita(L.) Hook.
  • Mucuna pruritaWight
  • Mucuna sericophyllaPerkins
  • Mucuna utilisWight
  • Mucuna velutinaHassk.
  • Negretia mitisBlanco
  • Stizolobium aterrimumPiper & Tracy
  • Stizolobium capitatum(Roxb.) Kuntze
  • Stizolobium cochinchinense(Lour.) Burk
  • Stizolobium deeringianumBort
  • Stizolobium hassjooPiper & Tracy
  • Stizolobium hirsutum(Wight & Arn.) Kuntze
  • Stizolobium niveum(Roxb.) Kuntze
  • Stizolobium pruriens(L.) Medik.
  • Stizolobium pruritum(Wight) Piper
  • Stizolobium utile(Wall. ex Wight) Ditmer
  • Stizolobium velutinum(Hassk.) Piper & Tracy

Mucuna pruriens is a tropical legume native to Africa and tropical Asia and widely naturalized and cultivated. [2] Its English common names include monkey tamarind, velvet bean, Bengal velvet bean, Florida velvet bean, Mauritius velvet bean, Yokohama velvet bean, cowage, cowitch, lacuna bean, and Lyon bean. [2]

The plant is notorious for the extreme itchiness it produces on contact, [3] particularly with the young foliage and the seed pods. It also produces many medium-sized red swollen bumps along with the itching. It has agricultural and horticultural value and is used in herbalism.

Description

Mucuna pruriens is an annual climbing shrub with long vines that can reach over 15 metres (50 feet) in length. When the plant is young, it is almost completely covered with fuzzy hairs, but when older, it is almost completely free of hairs. The leaves are tripinnate, ovate, reverse ovate, rhombus-shaped or widely ovate. The sides of the leaves are often heavily grooved and the tips are pointy. In young specimens, both sides of the leaves have hairs. The stems of the leaflets are 2–3 millimetres (11618 inch) long. Additional adjacent leaves are present and are about 5 mm (14 in) long.

The flower heads take the form of axially arrayed panicles. They are 15–32 centimetres (6–13 in) long and have two or three, or many flowers, which can be white, lavender, or purple. The accompanying leaves are about 12.5 mm (12 in) long; the flower stand axes are from 2.5–5 mm (18316 in). The bell is 7.5–9 mm (51638 in) long and silky. The sepals are longer or of the same length as the shuttles. The crown is purplish or white. The flag is 1.5 mm (116 in) long. The wings are 2.5–3.8 cm (1–1+12 in) long.

In the fruit-ripening stage, a 4–13 cm (2–5 in) long, 1–2 cm (3834 in) wide, unwinged, leguminous fruit develops. There is a ridge along its length and the husk is covered in loose, orange hairs that cause a severe itch if they contact skin. [4] [5] The pods carry up to seven seeds, which are shiny black or brown drift seeds. They are flattened uniform ellipsoids, 1–1.9 cm (3834 in) long, .8–1.3 cm (3812 in) wide and 4–6.5 cm (2–3 in) thick. The hilum , the base of the funiculus (connection between placenta and plant seeds) is a surrounded by a significant arillus (fleshy seed shell). The dry weight of the seeds is 55–85 grams (2–3 ounces)/100 seeds. [6]

Chemistry

The seeds of the plant contain about 3.1–6.1% L-DOPA . [7] M. pruriens var. pruriens has the highest content of L-DOPA. An average of 52.11% degradation of L-DOPA into damaging quinones and reactive oxygen species was found in seeds of M. pruriens varieties. [8]

Taxonomy

Subspecies

Varieties

Itch-inducing properties

The hairs lining the seed pods contain serotonin and the protein mucunain, which cause severe itching when the pods are touched. [3] [7] [11] The calyx below the flowers is also a source of itchy spicules and the stinging hairs on the outside of the seed pods are used in some brands of itching powder. [3] [12] Scratching the exposed area can spread the itching to other areas touched, which can cause blindness if in the area of the eyes. [13] Once this happens, the subject tends to scratch vigorously and uncontrollably and for this reason the local populace in northern Mozambique refer to the beans as "mad beans" (feijões malucos). The seed pods are known as "Devil Beans" in Nigeria. [14]

Uses

In many parts of the world, M. pruriens is used as an important forage, fallow and green manure crop. [15] Since the plant is a legume, it fixes nitrogen and fertilizes soil. In Indonesia, particularly Java, the beans are eaten and widely known as 'Benguk'. The beans can also be fermented to form a food similar to tempeh and known as Benguk tempe or 'tempe Benguk'.

M. pruriens is a widespread fodder plant in the tropics. To that end, the whole plant is fed to animals as silage, dried hay or dried seeds. M. pruriens silage contains 11–23% crude protein, 35–40% crude fiber, and the dried beans 20–35% crude protein. It also has use in the countries of Benin and Vietnam as a biological control for problematic Imperata cylindrica grass. [15] M. pruriens is said to not be invasive outside its cultivated area. [15] However, the plant is invasive within conservation areas of South Florida, where it frequently invades disturbed land and rockland hammock edge habitats. Cooked fresh shoots or beans can also be eaten. The plant contains relatively high (3–7% dry weight) levels of L-DOPA, [16] which some people are sensitive to; it can cause nausea, vomiting, cramping, arrhythmias, and hypotension. Up to 88% of the L-DOPA can be extracted from M. pruriens by boiling and soaking for approximately 48 hours. The efficiency of the process can be slightly improved by using approximately 0.25–0.50% sodium bicarbonate. [17]

Traditional medicine

The plant and its extracts have long been used in tribal communities as an antidote for snakebite. More recently, its effects against bites by Naja (cobra), [18] Echis (saw-scaled viper), [19] Calloselasma (Malayan pit viper), and Bungarus (krait) species have been studied.[ citation needed ] It has been investigated as a treatment for Parkinson's disease [20] due to its high L-DOPA content, [21] [16] while the seeds have been recognized for their ability to significantly alleviate neurotoxicity associated with the condition. [22]

The seeds have also been used for treating mood disorders, as well as for sexual dysfunction in Tibb-e-Unani [23] and Ayurvedic medicine.[ citation needed ]

The dried leaves of M. pruriens are sometimes smoked.[ why? ] [5]

See also

Related Research Articles

<span class="mw-page-title-main">Bean</span> Seed of one of several genera of the plant family Fabaceae

A bean is the seed of several plants in the family Fabaceae, which are used as vegetables for human or animal food. They can be cooked in many different ways, including boiling, frying, and baking, and are used in many traditional dishes throughout the world.

<span class="mw-page-title-main">Dopamine</span> Organic chemical that functions both as a hormone and a neurotransmitter

Dopamine is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. Dopamine constitutes about 80% of the catecholamine content in the brain. It is an amine synthesized by removing a carboxyl group from a molecule of its precursor chemical, L-DOPA, which is synthesized in the brain and kidneys. Dopamine is also synthesized in plants and most animals. In the brain, dopamine functions as a neurotransmitter—a chemical released by neurons to send signals to other nerve cells. Neurotransmitters are synthesized in specific regions of the brain, but affect many regions systemically. The brain includes several distinct dopamine pathways, one of which plays a major role in the motivational component of reward-motivated behavior. The anticipation of most types of rewards increases the level of dopamine in the brain, and many addictive drugs increase dopamine release or block its reuptake into neurons following release. Other brain dopamine pathways are involved in motor control and in controlling the release of various hormones. These pathways and cell groups form a dopamine system which is neuromodulatory.

<i>Vicia faba</i> Species of plant in the pea and bean family Fabaceae

Vicia faba, commonly known as the broad bean, fava bean, or faba bean, is a species of vetch, a flowering plant in the pea and bean family Fabaceae. It is widely cultivated as a crop for human consumption, and also as a cover crop. Varieties with smaller, harder seeds that are fed to horses or other animals are called field bean, tic bean or tick bean. Horse bean, Vicia faba var. equinaPers., is a variety recognized as an accepted name. This legume is very common in Southern European, Northern European, East Asian, Latin American and North African cuisines.

<span class="mw-page-title-main">Lima bean</span> Species of plant

A lima bean, also commonly known as butter bean, sieva bean, double bean or Madagascar bean, is a legume grown for its edible seeds or beans.

<i>Phaseolus vulgaris</i> Species of plant

Phaseolus vulgaris, the common bean, is a herbaceous annual plant grown worldwide for its edible dry seeds or green, unripe pods. Its leaf is also occasionally used as a vegetable and the straw as fodder. Its botanical classification, along with other Phaseolus species, is as a member of the legume family Fabaceae. Like most members of this family, common beans acquire the nitrogen they require through an association with rhizobia, which are nitrogen-fixing bacteria.

<i>Vigna subterranea</i> Species of plant

Vigna subterranea is a member of the family Fabaceae. Its name is derived from the Bambara ethnic group. The plant originated in West Africa. As a food and source of income, the Bambara groundnut is considered to be the third most important leguminous crop in those African countries where it is grown, after peanut and cowpea. The crop is mainly cultivated, sold and processed by women, and is, thus, particularly valuable for female subsistence farmers.

<small>L</small>-DOPA Chemical compound

l-DOPA, also known as levodopa and l-3,4-dihydroxyphenylalanine, is made and used as part of the normal biology of some plants and animals, including humans. Humans, as well as a portion of the other animals that utilize l-DOPA, make it via biosynthesis from the amino acid l-tyrosine. l-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), which are collectively known as catecholamines. Furthermore, l-DOPA itself mediates neurotrophic factor release by the brain and CNS. In some plant families, l-DOPA is the central precursor of a biosynthetic pathway that produces a class of pigments called betalains. l-DOPA can be manufactured and in its pure form is sold as a psychoactive drug with the INN levodopa; trade names include Sinemet, Pharmacopa, Atamet, and Stalevo. As a drug, it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia.

<i>Mucuna</i> Genus of plants

Mucuna is a genus of around 114 accepted species of climbing lianas (vines) and shrubs of the family Fabaceae: tribe Phaseoleae, typically found in tropical and subtropical forests in the Americas, sub-Saharan Africa, southern, southeastern, and eastern Asia, New Guinea, Australia, and the Pacific Islands.

<i>Lablab</i> Species of plant

Lablab purpureus is a species of bean in the family Fabaceae. It is native to sub-Saharan Africa and India and it is cultivated throughout the tropics for food. English language common names include hyacinth bean, lablab-beanbonavist bean/pea, dolichos bean, seim or sem bean, lablab bean, Egyptian kidney bean, Indian bean, bataw and Australian pea. Lablab is a monotypic genus.

<span class="mw-page-title-main">Mucunain</span>

The proteolytic enzyme mucunain is a protein in the tissues of certain legumes of the genus Mucuna, especially velvet bean.

<i>Senna tora</i> Species of flowering plant

Senna tora is a plant species in the family Fabaceae and the subfamily Caesalpinioideae. Its name is derived from its Sinhala name tora (තෝර). It grows wild in most of the tropics and is considered a weed in many places. Its native range is in Central America. Its most common English name is sickle senna or sickle wild sensitive-plant. Other common names include sickle pod, tora, coffee pod and foetid cassia. It is often confused with Chinese senna or sickle pod, Senna obtusifolia.

<i>Moringa oleifera</i> Species of flowering tree

Moringa oleifera is a fast-growing, drought-resistant tree of the family Moringaceae, native to the Indian subcontinent and used extensively in South and Southeast Asia. Common names include moringa, drumstick tree, horseradish tree, or malunggay.

<i>Banksia blechnifolia</i> Proteaceae of Western Australia

Banksia blechnifolia is a species of flowering plant in the genus Banksia found in Western Australia. It was first described by Victorian state botanist Ferdinand von Mueller in 1864, and no subspecies are recognised. It gained its specific name as its leaves are reminiscent of a fern (Blechnum). B. blechnifolia is one of several closely related species that grow as prostrate shrubs, with horizontal stems and leathery, upright leaves. The red-brown flower spikes, known as inflorescences, are up to 20 centimetres (8 in) high and appear from September to November in the Australian spring. As the spikes age, each turns grey and develops as many as 25 woody seed pods, known as follicles.

Itching powder is a powder or powder-like substance that induces itching when applied onto human skin. This is usually done as a practical joke or prank to an unsuspecting victim.

<i>Prosopis velutina</i> Species of tree

Prosopis velutina, commonly known as velvet mesquite, is a small to medium-sized tree. It is a legume adapted to a dry, desert climate. Though considered to be a noxious weed in states outside its natural range, it plays a vital role in the ecology of the Sonoran Desert.

<i>Strophostyles helvola</i> Species of legume

Strophostyles helvola, commonly called amberique-bean, annual sand bean, or trailing fuzzybean is a species of flowering plant in the legume family. It is native to eastern Canada and the eastern United States.

<span class="mw-page-title-main">Stinging plant</span> Plant with hairs (trichomes) on its leaves or stems

A stinging plant or a plant with stinging hairs is a plant with hairs (trichomes) on its leaves or stems that are capable of injecting substances that cause pain or irritation.

<i>Mucuna monosperma</i> Species of legume

Mucuna monosperma, commonly known as negro beans in India, or deer-eye beans, donkey-eye beans, or ox-eye beans, is a large woody climber from the family Fabaceae. The plant has three layers; a brown pod covered in small hairs, curved petals usually colored purple and black round-shaped beans. Small hairs on the pod can irritate the skin.The petals of the Muncuna monnosperma flower opens at night and closes in the morning. It is found in India, including the eastern Himalayas, the northeastern states, and the Andaman and Nicobar Islands, Sri Lanka, Bangladesh, Myanmar, and Thailand. Its natural habitat is evergreen forests, and it commonly grows near swamps or along streams.

<i>Mucuna gigantea</i> Species of plant in the family Fabaceae

Mucuna gigantea, commonly known as burny bean, burney bean, velvet bean or sea bean is a species of liana from the legume family Fabaceae. Its natural range roughly follows the perimeter of the Indian Ocean and includes Africa, India, Malesia, New Guinea and northern Australia. Many parts of the plant - in particular the new growth, flowers and fruit - are covered in fine irritant hairs.

<i>Mucuna urens</i> Species of plant

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References

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  22. Singh, Surya P.; Gedda, Mallikarjuna R.; Jadhav, Jyoti P.; Patil, Ravishankar R.; Zahra, Walia; Singh, Saumitra S.; Birla, Hareram; Rai, Sachchida N. (2017). "Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson's Disease through NF-κB/pAKT Signaling Pathways". Frontiers in Aging Neuroscience. 9: 421. doi: 10.3389/fnagi.2017.00421 . ISSN   1663-4365. PMC   5742110 . PMID   29311905.
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