PUM3

PUM3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4WZR, 4WZW
Identifiers
Aliases	PUM3 , D19Bwg1357e, 1110069H02Rik, AA675048, Kiaa0020, HA-8, HLA-HA8, PEN, PUF-A, PUF6, XTP5, KIAA0020, pumilio RNA binding family member 3
External IDs	OMIM: 609960; MGI: 106253; HomoloGene: 5762; GeneCards: PUM3; OMA:PUM3 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9p24.2 Start 2,720,469 bp [1] End 2,844,095 bp [1]
Gene location (Mouse) Chr. Chromosome 19 (mouse) [2] Band 19 C1|19 21.96 cM Start 27,366,098 bp [2] End 27,407,225 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon mucosa of transverse colon mucosa of esophagus gonad testicle olfactory zone of nasal mucosa left ovary minor salivary glands body of pancreas right ovary Top expressed in Paneth cell renal corpuscle endothelial cell of lymphatic vessel epiblast primitive streak medullary collecting duct internal carotid artery ureter abdominal wall hair follicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding mRNA binding RNA binding Cellular component endoplasmic reticulum nucleus nucleoplasm nucleolus chromosome Biological process regulation of protein ADP-ribosylation regulation of translation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9933 52874 Ensembl ENSG00000080608 ENSMUSG00000041360 UniProt Q15397 Q8BKS9 RefSeq (mRNA) NM_001031691 NM_014878 NM_177474 RefSeq (protein) NP_055693 NP_803425 Location (UCSC) Chr 9: 2.72 – 2.84 Mb Chr 19: 27.37 – 27.41 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

pumilio RNA binding family member 3 (previously KIAA0020 ^[5] ) is a protein that in humans is encoded by the PUM3 gene. ^{[6] [7] [8]}

References

1. GRCh38: Ensembl release 89: ENSG00000080608 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000041360 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "PUM3 Symbol Report | HUGO Gene Nomenclature Committee". www.genenames.org. Retrieved 2017-01-24.
6. Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (Dec 1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Research. 1 (1): 27–35. doi: 10.1093/dnares/1.1.27 . PMID   7584026.
7. Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (Dec 1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)". DNA Research. 1 (1): 47–56. doi: 10.1093/dnares/1.1.47 . PMID   7584028.
8. "Entrez Gene: KIAA0020 KIAA0020".

Further reading

• Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Hoja MR, Wahlestedt C, Höög C (August 2000). "A visual intracellular classification strategy for uncharacterized human proteins". Experimental Cell Research. 259 (1): 239–46. doi:10.1006/excr.2000.4948. PMID   10942595.
• Brickner AG, Warren EH, Caldwell JA, Akatsuka Y, Golovina TN, Zarling AL, Shabanowitz J, Eisenlohr LC, Hunt DF, Engelhard VH, Riddell SR (January 2001). "The immunogenicity of a new human minor histocompatibility antigen results from differential antigen processing". The Journal of Experimental Medicine. 193 (2): 195–206. doi:10.1084/jem.193.2.195. PMC   2193344 . PMID   11148223.
• Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (January 2002). "Directed proteomic analysis of the human nucleolus". Current Biology. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.
• Warren EH, Otterud BE, Linterman RW, Brickner AG, Engelhard VH, Leppert MF, Martin PJ, Riddell SR (April 2002). "Feasibility of using genetic linkage analysis to identify the genes encoding T cell-defined minor histocompatibility antigens". Tissue Antigens. 59 (4): 293–303. doi:10.1034/j.1399-0039.2002.590407.x. PMID   12135428.
• Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (November 2002). "Functional proteomic analysis of human nucleolus". Molecular Biology of the Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC   133617 . PMID   12429849.
• Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (January 2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.