Pinosylvin synthase

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pinosylvin synthase
Identifiers
EC no. 2.3.1.146
CAS no. 72994-49-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a pinosylvin synthase (EC 2.3.1.146) is an enzyme that catalyzes the chemical reaction

3 malonyl-CoA + cinnamoyl-CoA 4 CoA + pinosylvin + 4 CO2

Thus, the two substrates of this enzyme are malonyl-CoA and cinnamoyl-CoA, whereas its 3 products are CoA, pinosylvin, and CO2. [1]

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing). Other names in common use include stilbene synthase, and pine stilbene synthase. [2] This enzyme participates in phenylpropanoid biosynthesis. [2]

References

  1. Gehlert R (1990). "Stilbene Synthase from Seedlings of Pinus sylvestris : Purification and Induction in Response to Fungal Infection" . Molecular Plant-Microbe Interactions. 3 (6): 444. Bibcode:1990MPMI....3..444G. doi:10.1094/MPMI-3-444.
  2. 1 2 Valletta A, Iozia LM, Leonelli F (January 2021). "Impact of Environmental Factors on Stilbene Biosynthesis". Plants. 10 (1): 90. Bibcode:2021Plnts..10...90V. doi: 10.3390/plants10010090 . PMC   7823792 . PMID   33406721.