Soy formula

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Soy formula is a substitute for human breast milk. It is a commercial product based on the proteins found in soybeans. Soy infant formula uses processed soybeans as its source of protein, and comes in powdered or liquid form. [1] Usually lactose-free, soy infant formula contains a different sugar. Infants who are intolerant of cows' milk protein may also be intolerant of soy protein. It differs from human breast milk in a number of ways. [2] Soy protein inhibits the absorption of iron. The soy-based formulas discussed by the World Health Organization reports that soy formula is fortified with iron to compensate for this effect. [3] One naturally occurring plant-based compound found in soy-based infant formula is phytic acid. It is also a strong inhibitor of iron absorption, though it can be removed in processing. It is not known how many manufacturers of soy-based formula incorporate this practice. China and Vietnam have regulated soy-based infant formulas to include NaFeEDTA (sodium-feric ethylenediaminetetraacetic acid) to fortify the formula and enhance the absorption of iron by the infant. When iron compounds are added to soy-based infant formula, the iron compound is encapsulated to prevent it from making the formula dark. [4]

Contents

Constituents

Genetically modified ingredients may be present in soy-based infant formula. It may also be of lower nutritional value. [5] Soy-based infant formula can have aluminum, phytates, and phytoestrogens (isoflavones) that might cause unanticipated effects. Other constituents are amino acids: such as taurine, methionine, and carnitine. Added minerals are phosphore, calcium, iron, and zinc. SIF also contains soy-isolate that supplies 95% of protein.

Indications

Breastfeeding is still the best option for feeding infants. [6] There are instances when breastfeeding is not possible and the use of formula is appropriate. [5]

Indications for the use of soy-based infant formula are galactosaemia and lactase deficiency. When a child develops an allergy to cows' milk, soy-based formula is used. SBF is less costly than other breast milk formula substitutes. [6]

History

Past reports of the effects of soy formula have suggested that a constituent of soy formula may affect reproductive functions. However, studies have shown that no correlation exists between the consumption of soy formula and abnormality in reproductive anatomy or function. [7] Soy-based infant formula has been used for over the past 100 years. By late 1800s and the early 1900s, supplementation of breastfeeding with formula was acceptable. [5] Soy-based formula was used as early as 1909. [6]

Allergies and other concerns

Soy-based infant formula is associated with allergies in infants. [8] Chronic food protein-induced enterocolitis syndrome (FPIES) has been observed in infants aged younger than three months who were fed with soy formula. [9] France has taken soy-based infant formula off the market. Soy-base formula accounts for about 20% of the infant formula purchased in the US. In New Zealand formula use is around 10%, and in Belgium and the UK and about 5%. [6]

See also

Related Research Articles

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Lactose intolerance is caused by a lessened ability or a complete inability to digest lactose, a sugar found in dairy products. Humans vary in the amount of lactose they can tolerate before symptoms develop. Symptoms may include abdominal pain, bloating, diarrhea, flatulence, and nausea. These symptoms typically start thirty minutes to two hours after eating or drinking something containing lactose, with the severity typically depending on the amount consumed. Lactose intolerance does not cause damage to the gastrointestinal tract.

<span class="mw-page-title-main">Soybean</span> Legume grown for its edible bean

The soybean, soy bean, or soya bean is a species of legume native to East Asia, widely grown for its edible bean, which has numerous uses.

<span class="mw-page-title-main">Infant formula</span> Manufactured food designed for feeding infants

Infant formula, also called baby formula, simply formula, baby milk or infant milk, is an ultra-processed food designed and marketed for feeding to babies and infants under 12 months of age, usually prepared for bottle-feeding or cup-feeding from powder or liquid. The U.S. Federal Food, Drug, and Cosmetic Act (FFDCA) defines infant formula as "a food which purports to be or is represented for special dietary use solely as a food for infants by reason of its simulation of human milk or its suitability as a complete or partial substitute for human milk".

<span class="mw-page-title-main">Casein</span> Family of proteins found in milk

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<span class="mw-page-title-main">Food allergy</span> Hypersensitivity reaction to a food

A food allergy is an abnormal immune response to food. The symptoms of the allergic reaction may range from mild to severe. They may include itchiness, swelling of the tongue, vomiting, diarrhea, hives, trouble breathing, or low blood pressure. This typically occurs within minutes to several hours of exposure. When the symptoms are severe, it is known as anaphylaxis. A food intolerance and food poisoning are separate conditions, not due to an immune response.

<span class="mw-page-title-main">Breast milk</span> Milk produced by the mammary glands in the breast of a human female

Breast milk or mother's milk is milk produced by mammary glands located in the breast of a human female. Breast milk is the primary source of nutrition for newborns, containing fat, protein, carbohydrates and variable minerals and vitamins. Breast milk also contains substances that help protect an infant against infection and inflammation, whilst also contributing to healthy development of the immune system and gut microbiome.

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<span class="mw-page-title-main">Milk substitute</span> Alternative substance that resembles milk

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<span class="mw-page-title-main">Soy allergy</span> Type of food allergy caused by soy

Soy allergy is a type of food allergy. It is a hypersensitivity to ingesting compounds in soy, causing an overreaction of the immune system, typically with physical symptoms, such as gastrointestinal discomfort, respiratory distress, or a skin reaction. Soy is among the eight most common foods inducing allergic reactions in children and adults. It has a prevalence of about 0.3% in the general population.

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Food protein-induced enterocolitis syndrome (FPIES) is a systemic, non IgE-mediated response to a specific trigger within food – most likely food protein. FPIES presents in two different forms: an acute form and a chronic form. In its acute form, FPIES presents with vomiting that usually begins 1 to 4 hours after trigger food ingestion. Vomiting is often followed by a paleness to the skin, lethargy, and potentially watery, perhaps blood-tinged diarrhea. In the severe form of acute FPIES, a person will vomit until dehydration and until a shock-like state, which occurs in 15% of patients. In its chronic form, which can be difficult to diagnose until a person has already met diagnostic criteria for acute FPIES, after repeated or regular ingestion of the trigger food, the person presents with chronic or episodic vomiting, failure to thrive, and watery, perhaps blood-tinged diarrhea. FPIES can potentially develop at any age but seems most commonly to develop within the first few years of life. FPIES has mainly been documented in young infants, but can exist in older children and adults. Some people develop both FPIES and an IgE-mediated type of reaction to the same food, and having FPIES can increase a person's risk of also developing IgE-mediated food allergies.

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References

  1. "Promoting Breastfeeding During Pregnancy – Step 3". World Health Organization. 7 August 2017. Archived from the original on 22 August 2017. Retrieved 7 August 2017 via www.ncbi.nlm.nih.gov.PD-icon.svg This article incorporates text from this source, which is in the public domain .
  2. Walker, Marsha (2011). Breastfeeding management for the clinician : using the evidence. Sudbury, Mass: Jones and Bartlett Publishers. ISBN   9780763766511.
  3. "Preventing and Controlling Iron Defiency Anaemia Through Primary Health Care". The World Health Organization. 1990. Archived from the original (PDF) on 8 August 2017. Retrieved 9 August 2017.
  4. "JIACI · Journal of Investigational Allergology and Clinical Immunology". Archived from the original (PDF) on 2017-08-08. Retrieved 2017-08-07.
  5. 1 2 3 Walker, Marsha (1 August 2015). "Formula Supplementation of Breastfed Infants: Helpful or Hazardous?". ICAN: Infant, Child, & Adolescent Nutrition . 7 (4): 198–207. doi: 10.1177/1941406415591208 .
  6. 1 2 3 4 Vandenplas, Yvan; De Greef, Elisabeth; Devreker, Thierry; Hauser, Bruno (1 February 2011). "Soy infant formula: is it that bad?". Acta Paediatrica. 100 (2): 162–166. doi:10.1111/j.1651-2227.2010.02021.x. PMID   20860705. S2CID   44418196.
  7. Andres, Aline; Moore, Mary B.; Linam, Leann E.; Casey, Patrick H.; Cleves, Mario A.; Badger, Thomas M. (1 May 2015). "Compared with Feeding Infants Breast Milk or Cow-Milk Formula, Soy Formula Feeding Does Not Affect Subsequent Reproductive Organ Size at 5 Years of Age". The Journal of Nutrition. 145 (5): 871–875. doi: 10.3945/jn.114.206201 . PMID   25761499.
  8. Nowak-Węgrzyn, Anna; Katz, Yitzhak; Mehr, Sam Soheil; Koletzko, Sibylle (1 May 2015). "Non–IgE-mediated gastrointestinal food allergy". Journal of Allergy and Clinical Immunology. 135 (5): 1114–1124. doi: 10.1016/j.jaci.2015.03.025 . PMID   25956013.
  9. Nowak-Węgrzyn, A; Jarocka-Cyrta, E; Moschione Castro, APB (2017). "Food Protein–Induced Enterocolitis Syndrome". Journal of Investigational Allergology and Clinical Immunology. 27 (1): 1–18. doi: 10.18176/jiaci.0135 . ISSN   1018-9068. PMID   28211341.

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