| Year | Single | Peak chart positions | Album |
|---|
US
[24] | US
Rock
[25] | US
A/C
[26] | AUS
[3] | CAN
[27] | GER
[28] | IRL
[29] | NLD
[30] | NZ
[6] | UK
[8] |
|---|
| 1981 | "Stop Draggin' My Heart Around"
(with Tom Petty and the Heartbreakers) | 3 | 2 | — | 10 | 5 | — | — | 43 | 11 | 50 | Bella Donna |
| "Leather and Lace" (with Don Henley) | 6 | 26 | 10 | 68 | 12 | — | — | — | 50 | — |
| 1982 | "Edge of Seventeen" | 11 | 4 | — | — | 11 | — | — | — | — | 86* |
| "After the Glitter Fades" | 32 | — | 36 | — | — | — | — | — | — | — |
| 1983 | "Stand Back" | 5 | 2 | — | 20 | 13 | 32 | — | 29 | — | — | The Wild Heart |
| "Enchanted" [airplay] | — | 12 | — | — | — | — | — | — | — | — |
"I Will Run to You" [airplay]
(with Tom Petty and the Heartbreakers) | — | 35 | — | — | — | — | — | — | — | — |
| "Nothing Ever Changes" [airplay] | — | 19 | — | — | — | — | — | — | — | — |
| "If Anyone Falls" | 14 | 8 | — | — | — | — | — | — | — | — |
"Nightbird"
(with Sandy Stewart) | 33 | 32 | 39 | — | — | — | — | — | — | — |
| 1985 | "Talk to Me" | 4 | 1 | 14 | 22 | 10 | 28 | — | — | 45 | 68 | Rock a Little |
| 1986 | "I Can't Wait" | 16 | 6 | — | 20 | 43 | 58 | 29 | — | 39 | 54 |
| "Has Anyone Ever Written Anything for You?" | 60 | — | 31 | — | 92 | — | — | — | — | 84 |
| "Imperial Hotel" | — | — | — | 99 | — | — | — | — | — | — |
| 1989 | "Rooms on Fire" | 16 | 1 | 16 | 23 | 9 | 46 | 17 | 20 | 12 | 16 | The Other Side of the Mirror |
| "Long Way to Go" | — | 11 | — | 65 | — | 60 | — | — | — | 60 |
| "Two Kinds of Love" (with Bruce Hornsby) | — | — | — | — | — | — | — | — | — | — |
| "Whole Lotta Trouble" | — | — | — | — | — | — | 22 | — | — | 62 |
| 1991 | "Sometimes It's a Bitch" | 56 | 7 | — | 18 | 20 | 55 | — | — | 39 | 40 | Timespace: The Best of Stevie Nicks |
| "Love's a Hard Game to Play" | — | — | — | — | — | — | — | — | — | — |
| "I Can't Wait" [re-issue] | — | — | — | — | — | — | — | — | — | 47 |
| 1994 | "Maybe Love Will Change Your Mind" | 57 | 36 | 17 | — | 8 | — | — | — | — | 42 | Street Angel |
| "Blue Denim" | — | — | — | — | 69 | — | — | — | — | — |
| 1998 | "If You Ever Did Believe" | — | — | — | — | — | — | — | — | — | — | Practical Magic: Music from the Motion Picture |
| 1998 | "Reconsider Me" | — | — | — | — | — | — | — | — | — | — | The Enchanted Works of Stevie Nicks |
| 2001 | "Every Day" [US promo] | — | — | 17 | — | — | — | — | — | — | — | Trouble in Shangri-La |
| "Planets of the Universe" | — | — | — | — | — | — | — | — | — | — |
| "Sorcerer" [US promo] | — | — | 21 | — | — | — | — | — | — | — |
| 2007 | "Rock and Roll" | — | — | — | — | — | — | — | — | — | — | Crystal Visions – The Very Best of Stevie Nicks |
"Landslide"
(with the Melbourne Symphony Orchestra) | — | — | — | — | — | — | — | — | — | — |
| "Stand Back" [re-issue] | — | — | — | — | — | — | — | — | — | — |
| 2009 | "Crash Into Me" | — | — | — | — | — | — | — | — | — | — | The Soundstage Sessions |
| 2011 | "Secret Love" | — | — | 20 [31] | — | — | — | — | — | — | — | In Your Dreams |
| "For What It's Worth" | — | — | 25 [32] | — | — | — | — | — | — | — |
| 2014 | "The Dealer" | — | — | — | — | — | — | — | — | — | — | 24 Karat Gold: Songs from the Vault |
| "Lady" | — | — | — | — | — | — | — | — | — | — |
| "Starshine" | — | — | — | — | — | — | — | — | — | — |
| "24 Karat Gold" | — | — | — | — | — | — | — | — | — | — |
| 2020 | "Show Them the Way" [33] | — | — | — | — | — | — | — | — | — | — | Non-album single |
| 2022 | "For What It's Worth" (Buffalo Springfield song) | — | — | — | — | — | — | — | — | — | — | Non-album single [34] |
| 2024 | "The Lighthouse" | — | — | — | — | — | — | — | — | — | — | The Lighthouse |
| "—" denotes the single failed to chart or wasn't released |
