Supine hypertension

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Supine hypertension
Specialty Cardiology, Neurology
Symptoms Elevated blood pressure when lying down
Complications Cardiovascular strain, risk of stroke
Causes Autonomic dysfunction; medications such as Midodrine and Droxidopa
Differential diagnosis Orthostatic hypotension
TreatmentMedication adjustment, positional therapy
FrequencyRare

Supine hypertension is a paradoxical elevation in blood pressure upon assuming a supine position from a standing or sitting position. [1] [2] [3] It is assumed to be a manifestation of disorders of the autonomic nervous system [4] or due to side effects of medications such as midodrine and droxidopa. [5] [6]

References

  1. ↑ Naschitz, J E; Slobodin, G; Elias, N; Rosner, I (April 2006). "The patient with supine hypertension and orthostatic hypotension: a clinical dilemma". Postgraduate Medical Journal. 82 (966): 246–253. doi:10.1136/pgmj.2005.037457. PMC   2579630 . PMID   16597811.
  2. ↑ Jordan, Jens; Biaggioni, Italo (March 2002). "Diagnosis and treatment of supine hypertension in autonomic failure patients with orthostatic hypotension". The Journal of Clinical Hypertension. 4 (2): 139–145. doi: 10.1111/j.1524-6175.2001.00516.x . PMC   8099208 . PMID   11927799. S2CID   1205857.
  3. ↑ Biaggioni, Italo (12 October 2017). "Treatment of Supine Hypertension in Autonomic Failure - Full Text View - ClinicalTrials.gov". clinicaltrials.gov. United States: ClinicalTrials.gov, United States National Library of Medicine . Retrieved 2019-12-01.
  4. ↑ Naschitz, J. E.; Slobodin, G.; Elias, N.; Rosner, I. (2006). "The patient with supine hypertension and orthostatic hypotension: A clinical dilemma". Postgraduate Medical Journal. 82 (966): 246–253. doi:10.1136/pgmj.2005.037457. PMC   2579630 . PMID   16597811.
  5. ↑ Chen, Jack J.; Han, Yi; Tang, Jonathan; Portillo, Ivan; Hauser, Robert A.; Dashtipour, Khashayar (2018). "Standing and Supine Blood Pressure Outcomes Associated with Droxidopa and Midodrine in Patients with Neurogenic Orthostatic Hypotension: A Bayesian Meta-analysis and Mixed Treatment Comparison of Randomized Trials". Annals of Pharmacotherapy. 52 (12): 1182–1194. doi:10.1177/1060028018786954. PMID   29972032. S2CID   49674644.
  6. ↑ Jordan, Jens; Fanciulli, Alessandra; Tank, Jens; Calandra-Buonaura, Giovanna; Cheshire, William P.; Cortelli, Pietro; Eschlboeck, Sabine; Grassi, Guido; Hilz, Max J. (August 2019). "Management of supine hypertension in patients with neurogenic orthostatic hypotension: scientific statement of the American Autonomic Society, European Federation of Autonomic Societies, and the European Society of Hypertension" . Journal of Hypertension. 37 (8). Wolters Kluwer: 1541–1546. doi:10.1097/HJH.0000000000002078. PMID   30882602. S2CID   81988272 . Retrieved 2019-12-01.
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