Terpinolene synthase

Terpinolene synthase
Identifiers
EC no.	4.2.3.113
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Terpinolene synthase (EC 4.2.3.113, ag9, PmeTPS2, LaLIMS_RR) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing, terpinolene-forming). ^{[1] [2] [3] [4] [5]} This enzyme catalyses the following chemical reaction

geranyl diphosphate ${\displaystyle \rightleftharpoons }$ terpinolene + diphosphate

This enzyme requires Mg²⁺.

References

1. Croteau R, Satterwhite DM (September 1989). "Biosynthesis of monoterpenes. Stereochemical implications of acyclic and monocyclic olefin formation by (+)- and (–)-pinene cyclases from sage". The Journal of Biological Chemistry. 264 (26): 15309–15. doi: 10.1016/S0021-9258(19)84827-5 . PMID   2768265.
2. Bohlmann J, Phillips M, Ramachandiran V, Katoh S, Croteau R (August 1999). "cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis)". Archives of Biochemistry and Biophysics. 368 (2): 232–43. doi:10.1006/abbi.1999.1332. PMID   10441373.
3. Fäldt J, Martin D, Miller B, Rawat S, Bohlmann J (January 2003). "Traumatic resin defense in Norway spruce (Picea abies): methyl jasmonate-induced terpene synthase gene expression, and cDNA cloning and functional characterization of (+)-3-carene synthase". Plant Molecular Biology. 51 (1): 119–33. doi:10.1023/A:1020714403780. PMID   12602896.
4. Huber DP, Philippe RN, Godard KA, Sturrock RN, Bohlmann J (June 2005). "Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii". Phytochemistry. 66 (12): 1427–39. Bibcode:2005PChem..66.1427H. doi:10.1016/j.phytochem.2005.04.030. PMID   15921711.
5. Landmann C, Fink B, Festner M, Dregus M, Engel KH, Schwab W (September 2007). "Cloning and functional characterization of three terpene synthases from lavender (Lavandula angustifolia)". Archives of Biochemistry and Biophysics. 465 (2): 417–29. doi:10.1016/j.abb.2007.06.011. PMID   17662687.

External links

• Terpinolene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)