2'-deoxymugineic-acid 2'-dioxygenase

2'-deoxymugineic-acid 2'-dioxygenase
Identifiers
EC no.	1.14.11.24
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

In enzymology, a 2'-deoxymugineic-acid 2'-dioxygenase (EC 1.14.11.24) is an enzyme that catalyzes the chemical reaction

2'-deoxymugineic acid + 2-oxoglutarate + O₂${\displaystyle \rightleftharpoons }$ mugineic acid + succinate + CO₂

The 3 substrates of this enzyme are 2'-deoxymugineic acid, 2-oxoglutarate, and O₂, whereas its 3 products are mugineic acid, (a compound related to azetidine-2-carboxylic acid) succinate, and CO₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with 2-oxoglutarate as one donor, and incorporation of one atom o oxygen into each donor. The systematic name of this enzyme class is 2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating). This enzyme is also called IDS3.

References

• Nakanishi H, Yamaguchi H, Sasakuma T, Nishizawa NK, Mori S (2000). "Two dioxygenase genes, Ids3 and Ids2, from Hordeum vulgare are involved in the biosynthesis of mugineic acid family phytosiderophores". Plant Mol. Biol. 44 (2): 199–207. doi:10.1023/A:1006491521586. PMID   11117263. S2CID   26139505.
• Mori S; Nakanishi, H; Takahashi, M; Kawasaki, S; Nishizawa, NK; Mori, S (2001). "In vivo evidence that Ids3 from Hordeum vulgare encodes a dioxygenase that converts 2'-deoxymugineic acid to mugineic acid in transgenic rice". Planta. 212 (5–6): 864–71. doi:10.1007/s004250000453. PMID   11346963. S2CID   22984843.