ecdysone 20-monooxygenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.14.99.22 | ||||||||
CAS no. | 55071-97-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Ecdysone 20-monooxygenase (EC 1.14.99.22) is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are ecdysone, an electron acceptor AH2, and O2, whereas its three products are 20-hydroxyecdysone, the reduction product A, and H2O. [1] [2] [3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating). Like other genes in the ecdysone synthesis pathway, it belongs to Cytochrome P450 Halloween genes, with the nickname shade, other names in common use include alpha-ecdysone C-20 hydroxylase, and ecdysone 20-hydroxylase. [4]
In enzymology, a 3-hydroxybenzoate 2-monooxygenase (EC 1.14.99.23) is an enzyme that catalyzes the chemical reaction
In enzymology, a 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase (EC 1.14.13.96) is an enzyme that catalyzes the chemical reaction
In enzymology, a camphor 5-monooxygenase (EC 1.14.15.1) is an enzyme that catalyzes the chemical reaction
In enzymology, a cholestanetriol 26-monooxygenase (EC 1.14.13.15) is an enzyme that catalyzes the chemical reaction
In enzymology, a deoxyhypusine monooxygenase (EC 1.14.99.29) is an enzyme that catalyzes the chemical reaction
In enzymology, a licodione synthase (EC 1.14.13.87) is an enzyme that catalyzes the chemical reaction
In enzymology, a lithocholate 6beta-hydroxylase (EC 1.14.13.94) is an enzyme that catalyzes the chemical reaction
In enzymology, a progesterone 11alpha-monooxygenase (EC 1.14.99.14) is an enzyme that catalyzes the chemical reaction
In enzymology, a quinine 3-monooxygenase (EC 1.14.13.67) is an enzyme that catalyzes the chemical reaction
In enzymology, a (R)-limonene 6-monooxygenase (EC 1.14.13.80) is an enzyme that catalyzes the chemical reaction
In enzymology, a steroid 11beta-monooxygenase (EC 1.14.15.4) is an enzyme that catalyzes the chemical reaction
In enzymology, a steroid 17alpha-monooxygenase (EC 1.14.99.9) is an enzyme that catalyzes the chemical reaction
In enzymology, a steroid 9alpha-monooxygenase (EC 1.14.99.24) is an enzyme that catalyzes the chemical reaction
In enzymology, a taxadiene 5alpha-hydroxylase (EC 1.14.99.37) is an enzyme that catalyzes the chemical reaction
In enzymology, a taxane 10beta-hydroxylase (EC 1.14.13.76) is an enzyme that catalyzes the chemical reaction
In enzymology, a taxane 13alpha-hydroxylase (EC 1.14.13.77) is an enzyme that catalyzes the chemical reaction
In enzymology, a trans-cinnamate 4-monooxygenase (EC 1.14.14.91) is an enzyme that catalyzes the chemical reaction
In enzymology, an unspecific monooxygenase (EC 1.14.14.1) is an enzyme that catalyzes the chemical reaction
The halloween genes are a set of genes identified in Drosophila melanogaster that influence embryonic development. All of the genes code for cytochrome P450 enzymes in the ecdysteroidogenic pathway (biosynthesis of ecdysone from cholesterol). Ecdysteroids such as 20-hydroxyecdysone and ecdysone influence many of the morphological, physiological, biochemical changes that occur during molting in insects.
Carotene epsilon-monooxygenase (EC 1.14.99.45, CYP97C1, LUT1) is an enzyme with systematic name alpha-carotene:oxygen oxidoreductase (3-hydroxylating). This enzyme catalyses the following chemical reaction