Tryptophan N-monooxygenase | |||||||||
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Identifiers | |||||||||
EC no. | 1.14.13.125 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Tryptophan N-monooxygenase (EC 1.14.13.125, tryptophan N-hydroxylase, CYP79B1, CYP79B2, CYP79B3) is an enzyme with systematic name L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating). [1] [2] [3] [4] This enzyme catalyses the following chemical reaction
Tryptophan N-monooxygenase is a heme-thiolate protein (P-450).
Glucobrassicin is a type of glucosinolate that can be found in almost all cruciferous plants, such as cabbages, broccoli, mustards, and woad. As for other glucosinolates, degradation by the enzyme myrosinase is expected to produce an isothiocyanate, indol-3-ylmethylisothiocyanate. However, this specific isothiocyanate is expected to be highly unstable, and has indeed never been detected. The observed hydrolysis products when isolated glucobrassicin is degraded by myrosinase are indole-3-carbinol and thiocyanate ion, which are envisioned to result from a rapid reaction of the unstable isothiocyanate with water. However, a large number of other reaction products are known, and indole-3-carbinol is not the dominant degradation product when glucosinolate degradation takes place in crushed plant tissue or in intact plants.
In enzymology, a secologanin synthase (EC 1.14.19.62, was wrongly classified as EC 1.3.3.9 in the past) is an enzyme that catalyzes the chemical reaction
In enzymology, a (+)-abscisic acid 8'-hydroxylase (EC 1.14.13.93) is an enzyme that catalyzes the chemical reaction
In enzymology, a hydroxyphenylacetonitrile 2-monooxygenase (EC 1.14.13.42) is an enzyme that catalyzes the chemical reaction
In enzymology, an isoflavone 2'-hydroxylase (EC 1.14.14.90, Formerly EC 1.14.13.89) is an enzyme that catalyzes the chemical reaction
In enzymology, a N-methylcoclaurine 3'-monooxygenase (EC 1.14.13.71) is an enzyme that catalyzes the chemical reaction
In enzymology, a tabersonine 16-hydroxylase (EC 1.14.13.73) is an enzyme that catalyzes the chemical reaction
In enzymology, a trans-cinnamate 4-monooxygenase (EC 1.14.14.91) is an enzyme that catalyzes the chemical reaction
In enzymology, a tryptophan 2-monooxygenase (EC 1.13.12.3) is an enzyme that catalyzes the chemical reaction
Tyrosine N-monooxygenase (EC 1.14.13.41, tyrosine N-hydroxylase, CYP79A1) is an enzyme with systematic name L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating). This enzyme catalyses the following chemical reaction
Ent-kaurene oxidase (EC 1.14.14.86, Formerly EC 1.14.13.78) is an enzyme with systematic name ent-kaur-16-ene,NADPH:oxygen oxidoreductase (hydroxylating). This enzyme catalyses the following chemical reaction
Epi-isozizaene 5-monooxygenase (EC 1.14.13.106, CYP170A1) is an enzyme with systematic name (+)-epi-isozizaene,NADPH:oxygen oxidoreductase (5-hydroxylating). This enzyme catalyses the following chemical reaction
3-Epi-6-deoxocathasterone 23-monooxygenase (EC 1.14.13.112, cytochrome P450 90C1, CYP90D1, CYP90C1) is an enzyme with systematic name 3-epi-6-deoxocathasterone,NADPH:oxygen oxidoreductase (C-23-hydroxylating). This enzyme catalyses the following chemical reaction
Isoleucine N-monooxygenase (EC 1.14.13.117, CYP79D3, CYP79D4) is an enzyme with systematic name L-isoleucine,NADPH:oxygen oxidoreductase (N-hydroxylating). This enzyme catalyses the following chemical reaction
Valine N-monooxygenase (EC 1.14.13.118, CYP79D1, CYP79D2) is an enzyme with systematic name L-valine,NADPH:oxygen oxidoreductase (N-hydroxylating). This enzyme catalyses the following chemical reaction
Phenylalanine N-monooxygenase (EC 1.14.14.40, phenylalanine N-hydroxylase, CYP79A2) is an enzyme with systematic name L-phenylalanine,NADPH:oxygen oxidoreductase (N-hydroxylating). This enzyme catalyses the following chemical reaction
Beta-amyrin 11-oxidase (EC 1.14.13.134, CYP88D6) is an enzyme with systematic name beta-amyrin,NADPH:oxygen oxidoreductase (hydroxylating). This enzyme catalyses the following chemical reaction
Amorpha-4,11-diene 12-monooxygenase (EC 1.14.13.158, CYP71AV1) is an enzyme with systematic name amorpha-4,11-diene,NADPH:oxygen oxidoreductase (12-hydroxylating). This enzyme catalyses the following chemical reaction
Indole-3-pyruvate monooxygenase (EC 1.14.13.168, YUC2 (gene), spi1 (gene)) is an enzyme with systematic name indole-3-pyruvate,NADPH:oxygen oxidoreductase (1-hydroxylating, decarboxylating). This enzyme catalyses the following chemical reaction
Camalexin (3-thiazol-2-yl-indole) is a simple indole alkaloid found in the plant Arabidopsis thaliana and other crucifers. The secondary metabolite functions as a phytoalexin to deter bacterial and fungal pathogens.