CYP27A1 is a gene encoding a cytochrome P450 oxidase, and is commonly known as sterol 27-hydroxylase. This enzyme is located in many different tissues where it is found within the mitochondria. It is most prominently involved in the biosynthesis of bile acids.
Cholesterol 7 alpha-hydroxylase also known as cholesterol 7-alpha-monooxygenase or cytochrome P450 7A1 (CYP7A1) is an enzyme that in humans is encoded by the CYP7A1 gene which has an important role in cholesterol metabolism. It is a cytochrome P450 enzyme, which belongs to the oxidoreductase class, and converts cholesterol to 7-alpha-hydroxycholesterol, the first and rate limiting step in bile acid synthesis.
Cholesterol 24-hydroxylase, also commonly known as cholesterol 24S-hydroxylase, cholesterol 24-monooxygenase, CYP46, or CYP46A1, is an enzyme that catalyzes the conversion of cholesterol to 24S-hydroxycholesterol. It is responsible for the majority of cholesterol turnover in the human central nervous system. The systematic name of this enzyme class is cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating).
Adrenal ferredoxin is a protein that in humans is encoded by the FDX1 gene. In addition to the expressed gene at this chromosomal locus (11q22), there are pseudogenes located on chromosomes 20 and 21.
Oxysterol-binding protein-related protein 5 is a protein that in humans is encoded by the OSBPL5 gene.
Cytochrome P450 3A43 is a protein that in humans is encoded by the CYP3A43 gene.
25-hydroxycholesterol 7-alpha-hydroxylase also known as oxysterol and steroid 7-alpha-hydroxylase is an enzyme that in humans is encoded by the CYP7B1 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
Cytochrome P450 2F1 is a protein that in humans is encoded by the CYP2F1 gene.
Oxysterol-binding protein 2 is a protein that in humans is encoded by the OSBP2 gene.
Cytochrome P450 4F12 is a protein that in humans is encoded by the CYP4F12 gene.
Oxysterol-binding protein-related protein 8 is a protein that in humans is encoded by the OSBPL8 gene.
ATP-binding cassette sub-family G member 4 is a protein that in humans is encoded by the ABCG4 gene.
Oxysterol-binding protein-related protein 2 is a protein that in humans is encoded by the OSBPL2 gene.
CYP2R1 is cytochrome P450 2R1, an enzyme which is the principal vitamin D 25-hydroxylase. In humans it is encoded by the CYP2R1 gene located on chromosome 11p15.2. It is expressed in the endoplasmic reticulum in liver, where it performs the first step in the activation of vitamin D by catalyzing the formation of 25-hydroxyvitamin D.
CYP26C1 is a protein which in humans is encoded by the CYP26C1gene.
CYP20A1 is a protein which in humans is encoded by the CYP20A1 gene.
CYP8B1 also known as sterol 12-alpha-hydroxylase is a protein which in humans is encoded by the CYP8B1 gene.
CYP4X1 is a protein which in humans is encoded by the CYP4X1 gene.
CYP4F22 is a protein that in humans is encoded by the CYP4F22 gene.
CYP2W1 is a protein that in humans is encoded by the CYP2W1 gene.
