2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase

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2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
Identifiers
EC no. 1.1.1.126
CAS no. 37250-55-8
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In enzymology, a 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase (EC 1.1.1.126) is an enzyme that catalyzes the chemical reaction

2-dehydro-3-deoxy-D-gluconate + NADP+ (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H+

Thus, the two substrates of this enzyme are 2-dehydro-3-deoxy-D-gluconate and NADP+, whereas its 3 products are (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase. Other names in common use include 2-keto-3-deoxy-D-gluconate dehydrogenase, and 2-keto-3-deoxygluconate dehydrogenase.

Related Research Articles

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<span class="mw-page-title-main">Ketol-acid reductoisomerase</span> Class of enzymes

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In enzymology, a 3-dehydro-L-gulonate 2-dehydrogenase (EC 1.1.1.130) is an enzyme that catalyzes the chemical reaction:

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References


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