2017 Uganda Marburg virus outbreak

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Uganda Marburg outbreak 2017
Initial case= 25 September 2017 [1]
Declared ended= 2 December 2017 [2]
Uganda Ug-map.png
Uganda
Uganda
Uganda (orthographic projection) Uganda (orthographic projection).svg
Uganda (orthographic projection)
Confirmed cases [3] 2
Probable cases [4] 1
Deaths [5] 3

The 2017 Uganda Marburg virus outbreak was confirmed by the World Health Organization (WHO) on 20 October 2017 after there had been an initial fatality due to the virus. [6]

Contents

The Ugandan Ministry of Health indicated that an individual had died of the virus on 19 October; the following day, 20 October, WHO released a press statement regarding the matter. The eastern part of the country is the affected area where the cases have occurred. [1] [3] On 22 October, it was reported that 55 individuals were under surveillance for the virus. [7] On 25 October, the number of individuals rose to 155 in terms of contact tracing [8]

Virology and epidemiology

Marburg virus Marburg virus.jpg
Marburg virus

According to the Centers for Disease Control and Prevention (CDC), the Marburg virus was first recognised in 1967. [9] In terms of diagnosis the presentation is similar to malaria or typhoid fever and therefore not easy to identify (diagnose). [10]

The Marburg virus is considered a filovirus, which is the same as the Ebola virus in terms of viral classification. [11] According to Mehedi, et al. macrophages, monocytes, and dendritic cells, are what the virus attacks due to their importance in the human bodies normal mechanism [12]

According to the World Health Organization there is currently no treatment for the disease. [13] As of 11 November 2017, according to the Ministry of Health no new cases have been reported to this point [14] the report originates from Kampala.

On 8 December the World Health Organization declared the end to the outbreak in the country of Uganda due to two 21-day quarantine periods [15]

Other outbreaks


The table lists a subset of the Marburg virus disease outbreaks, which have occurred specifically in Uganda:

Marburg virus disease outbreaks in Uganda
YearCountryVirusHuman casesHuman deaths Case fatality rate Reference
2007Flag of Uganda.svg  Uganda MARV & RAVV 2150% [16]
2008Flag of Uganda.svg  Uganda Flag of the Netherlands.svg  Netherlands Flag of the United States (23px).png  United States MARV2150% [17]
2012Flag of Uganda.svg  Uganda MARV18950% [18]
2014Flag of Uganda.svg  Uganda MARV11100% [19]
2017Flag of Uganda.svg  Uganda MARV33100% [2]

See also

References

  1. 1 2 Athumani, Halima (19 October 2017). "Uganda Confirms 1 Death From Ebola-like Marburg Virus". VOA. Archived from the original on 21 October 2017. Retrieved 21 October 2017.
  2. 1 2 "Uganda controls deadly Marburg fever outbreak, WHO says". ABC News. Archived from the original on 8 December 2017. Retrieved 8 December 2017.
  3. 1 2 "Ebola-like Marburg virus kills two in Uganda". Daily Nation. Archived from the original on 21 October 2017. Retrieved 21 October 2017.
  4. ↑ "Marburg virus disease – Uganda and Kenya". World Health Organization. Archived from the original on 17 November 2017. Retrieved 16 November 2017.
  5. ↑ "Uganda – Marburg Virus Disease (DG ECHO, Ministry of Health)( ECHO Daily Flash of 06 November 2017)". ReliefWeb. 6 November 2017. Archived from the original on 6 November 2017. Retrieved 6 November 2017.
  6. ↑ "WHO supports containment of rare virus on Uganda-Kenya border". World Health Organization. Archived from the original on 23 October 2017. Retrieved 21 October 2017.
  7. ↑ "Marburg: 55 people under surveillance". The Observer – Uganda. 22 October 2017. Archived from the original on 23 October 2017. Retrieved 23 October 2017.
  8. ↑ "Marburg virus disease – Uganda". World Health Organization. Archived from the original on 26 October 2017. Retrieved 16 November 2017.
  9. ↑ "Ebola & Marburg | NIH: National Institute of Allergy and Infectious Diseases". www.niaid.nih.gov. Archived from the original on 28 April 2024. Retrieved 21 October 2017.
  10. ↑ "Marburg Hemorrhagic Fever (Marburg HF) | CDC". www.cdc.gov. Archived from the original on 19 October 2022. Retrieved 21 October 2017.
  11. ↑ Bente, Dennis; Gren, Jason; Strong, James E.; Feldmann, Heinz (2009). "Disease modeling for Ebola and Marburg viruses". Disease Models & Mechanisms. 2 (1–2): 12–17. doi:10.1242/dmm.000471. ISSN   1754-8403. PMC   2615158 . PMID   19132113.
  12. ↑ Mehedi, Masfique; Groseth, Allison; Feldmann, Heinz; Ebihara, Hideki (2011). "Clinical aspects of Marburg hemorrhagic fever". Future Virology. 6 (9): 1091–1106. doi:10.2217/fvl.11.79. ISSN   1746-0794. PMC   3201746 . PMID   22046196.
  13. ↑ "Marburg virus disease". World Health Organization. Archived from the original on 28 October 2017. Retrieved 29 October 2017.
  14. ↑ "Press Release | Ministry of Health". health.go.ug. Archived from the original on 15 November 2017. Retrieved 16 November 2017.
  15. ↑ "Uganda ends Marburg virus disease outbreak". ReliefWeb. 8 December 2017. Archived from the original on 8 December 2017. Retrieved 8 December 2017.
  16. ↑ "WHO | Marburg haemorrhagic fever in Uganda". www.who.int. Archived from the original on 8 October 2014. Retrieved 23 October 2017.
  17. ↑ "Imported Case of Marburg Hemorrhagic Fever --- Colorado, 2008". cdc.gov. Archived from the original on 23 May 2017. Retrieved 23 October 2017.
  18. ↑ "WHO | Marburg haemorrhagic fever in Uganda – update". www.who.int. Archived from the original on 10 August 2014. Retrieved 29 October 2017.
  19. ↑ "WHO | Marburg virus disease – Uganda". www.who.int. Archived from the original on 17 November 2014. Retrieved 29 October 2017.

Further reading

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