3-hydroxypropionyl-CoA dehydratase

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3-hydroxypropionyl-CoA dehydratase
Identifiers
EC no. 4.2.1.116
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ExPASy NiceZyme view
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MetaCyc metabolic pathway
PRIAM profile
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NCBI proteins

3-hydroxypropionyl-CoA dehydratase (EC 4.2.1.116) is an enzyme with systematic name 3-hydroxypropionyl-CoA hydro-lyase. [1] [2] This enzyme catalyses the following chemical reaction

3-hydroxypropanoyl-CoA acrylyl-CoA + H2O

This enzyme catalyses a step in the 3-hydroxypropionate/4-hydroxybutyrate cycle.

References

  1. Berg IA, Kockelkorn D, Buckel W, Fuchs G (December 2007). "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea". Science. 318 (5857): 1782–6. Bibcode:2007Sci...318.1782B. doi:10.1126/science.1149976. PMID   18079405.
  2. Teufel R, Kung JW, Kockelkorn D, Alber BE, Fuchs G (July 2009). "3-hydroxypropionyl-coenzyme A dehydratase and acryloyl-coenzyme A reductase, enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in the Sulfolobales". Journal of Bacteriology. 191 (14): 4572–81. doi:10.1128/JB.00068-09. PMC   2704735 . PMID   19429610.