Ancient East Eurasians

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The term Ancient East Eurasian, alternatively also known as East Eurasian or Eastern Eurasian, is used in population genomics to describe the genetic ancestry and phylogenetic relationship of diverse populations primarily living in the Asia-Pacific region, belonging to the "Eastern Eurasian clade" of human genetic diversity, [1] [2] [3] [4] [5] [6] and which can be associated with the Initial Upper Paleolithic (IUP) wave, following the Out of Africa migration (>60kya). [4] [6]

Contents

Dispersal

Repetitive expansions into Eurasia from a population Hub OoA. Representative samples dated between 45 and 40 ka across Eurasia can be ascribed to a population movement with uniform genetic features and material culture consistent with an IUP affiliation. Repetitive expansions into Eurasia from a population Hub OoA.jpg
Repetitive expansions into Eurasia from a population Hub OoA. Representative samples dated between 45 and 40 ka across Eurasia can be ascribed to a population movement with uniform genetic features and material culture consistent with an IUP affiliation.

Modern humans of the Initial Upper Paleolithic wave (IUP) are suggested to have expanded from a population hub through a star-like expansion pattern (>45kya), and are linked to the "East Eurasian" lineage, broadly ancestral to modern populations in Eastern Eurasia, Oceania, and the Americas, notably East Asians, Southeast Asians, Indigenous Siberians, Aboriginal Australians, Papuans, Pacific Islanders, and mostly in Indigenous Americans, and partly in South Asians and Central Asians. While certain Initial Upper Paleolithic populations represented by specimens found in Central Asia and Europe, such as the Ust'-Ishim man, Bacho Kiro or Oase 2, are inferred to have used inland routes, the ancestors of all modern East Eurasian populations are inferred to have used a Southern dispersal route through South Asia, where they subsequently diverged rapidly. [7] [8] [9] [10] [11] [12] [13] [14]

Ancient East Eurasians diverged from Ancient West Eurasians around 46,000 years ago, and started to diversify themselves 45,000 years ago. [15] This divergence most likely occurred in the Persian Plateau. [16]

Inferred model for the phylogenetic substructure of Eastern Eurasian populations. Phylogenetic structure of Eastern Eurasians.png
Inferred model for the phylogenetic substructure of Eastern Eurasian populations.

Lineages

Major East Eurasian ancestry lineages which contributed to modern human populations include the following: [8]

Estimated ancestry components among selected modern populations per Changmai et al. (2022). K6 human genetic ancestries.png
Estimated ancestry components among selected modern populations per Changmai et al. (2022).

The Australasian, Ancient Ancestral South Indian, and East and Southeast Asian lineages display a closer genetic relationship to each other than to any non-Asian lineages, and together represent the main branches of "Asian-related ancestry", which diverged from each other >40kya. [8] The Australasian lineage however received higher archaic admixture in the Oceania region, and may also harbor some small amounts of "xOoA" admixture from an earlier human dispersal, which did not contribute to any other human population. Alternatively, Australasians can be described as nearly equally admixture between a "Basal East Asian" source (represented by Tianyuan) and a deeper East Eurasian lineage not sampled yet. [7] [1] [8] :11

Traces of an unsampled deeply diverged East Eurasian lineage can be observed in the genome of ancient and modern inhabitants of the Tibetan Plateau. While modern Tibetans mostly derive their ancestry from a northern East Asian source (specifically Yellow River farmers), a minor, but significant contribution stems from a deeply diverged East Eurasian local "Ghost population" that was distinct from other deeply diverged lineages such as Ust'Ishim, Hoabinhian/Onge or Tianyuan, representing the local Paleolithic population of the Tibetan Plateau. [20] [21]

Deeper IUP-associated East Eurasian lineages have been associated with the remains of the Ust'-Ishim man from Siberia, and the Oase and Bacho Kiro cave specimens in southeastern Europe, and represent early inland migrations, deeply diverged from all other East Eurasian populations. These deep East Eurasian populations did not contribute to later Eurasian populations, except small contributions to the Goyet Caves specimen of Europe. The exact substructure and relationship between these deeper East Eurasian lineages is not well resolved yet. [7] [22]

Related Research Articles

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<span class="mw-page-title-main">Bacho Kiro cave</span> Archaeological site in Bulgaria

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<span class="mw-page-title-main">Ancient Beringian</span> Extinct archaeogenetic lineage

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<span class="mw-page-title-main">Ancient Paleo-Siberian</span> Human archaeogenetic lineage

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References

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  14. Hao, Li (2022). "Exploring the southern dispersal routes of early modern humans". Acta Anthropologica Sinica. 41 (4): 630–648. Based on the above findings, some scholars have proposed that the specific diffusion path of early modern humans in the south was quite complex, possibly including both coastal routes (some sites may be submerged under the sea) and inland routes. Field J et al.'s minimum cost path analysis based on GIS technology confirmed this: early modern humans formed multiple paths during their diffusion, and their inland paths were mostly based on rivers as migration corridors, such as the Indus River and the Narmada River in the Indian Peninsula.
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  20. Liu, Chi-Chun; Witonsky, David; Gosling, Anna; Lee, Ju Hyeon; Ringbauer, Harald; Hagan, Richard; Patel, Nisha; Stahl, Raphaela; Novembre, John; Aldenderfer, Mark; Warinner, Christina; Di Rienzo, Anna; Jeong, Choongwon (8 March 2022). "Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors". Nature Communications. 13 (1): 1203. Bibcode:2022NatCo..13.1203L. doi:10.1038/s41467-022-28827-2. ISSN   2041-1723. PMC   8904508 . PMID   35260549. our results reject previously suggested sources of gene flow into the Tibetan lineage13,35,36, including deeply branching Eastern Eurasian lineages, such as the 45,000-year-old Ust'-Ishim individual from southern Siberia, the 40,000-year-old Tianyuan individual from northern China, and Hoabinhian/Onge-related lineages in southeast Asia (Supplementary Fig. 10), suggesting instead that it represents yet another unsampled lineage within early Eurasian genetic diversity. This deep Eurasian lineage is likely to represent the Paleolithic genetic substratum of the Plateau populations.
  21. Wang, Hongru; Yang, Melinda A.; Wangdue, Shargan; Lu, Hongliang; Chen, Honghai; Li, Linhui; Dong, Guanghui; Tsring, Tinley; Yuan, Haibing; He, Wei; Ding, Manyu; Wu, Xiaohong; Li, Shuai; Tashi, Norbu; Yang, Tsho (15 March 2023). "Human genetic history on the Tibetan Plateau in the past 5100 years". Science Advances. 9 (11): eadd5582. Bibcode:2023SciA....9D5582W. doi:10.1126/sciadv.add5582. ISSN   2375-2548. PMC   10022901 . PMID   36930720.
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