Biochanin-A reductase

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biochanin-A reductase
Identifiers
EC no. 1.3.1.46
CAS no. 112198-90-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, biochanin-A reductase (EC 1.3.1.46) is an enzyme that catalyzes the chemical reaction

 
 
H+
 
Biochanin-A reductase
H+
 
 
 

The three substrates of this enzyme are biochanin A, reduced nicotinamide adenine dinucleotide phosphate (NADPH), and a proton. Its products are 2,3-dihydrobiochanin A and oxidised NADP+. [1] [2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is dihydrobiochanin-A:NADP+ Delta2-oxidoreductase. This enzyme participates in isoflavonoid biosynthesis.

References

  1. Enzyme 1.3.1.46 at KEGG Pathway Database.
  2. Tiemann K, Hinderer W, Barz W (1987). "Isolation of NADPH:isoflavone oxidoreductase, a new enzyme of pterocarpan biosynthesis in cell suspensions of Cicer arietinum". FEBS Lett. 213 (2): 324–328. doi: 10.1016/0014-5793(87)81515-6 .