CDP-glucose 4,6-dehydratase

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CDP-glucose 4,6-dehydratase
Identifiers
EC no. 4.2.1.45
CAS no. 37259-55-5
Databases
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BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
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The enzyme CDP-glucose 4,6-dehydratase (EC 4.2.1.45) catalyzes the chemical reaction

Contents

CDP-glucose CDP-4-dehydro-6-deoxy-D-glucose + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. This enzyme participates in starch and sucrose metabolism. It employs one cofactor, NAD+.

Nomenclature

The systematic name of this enzyme class is CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming). Other names in common use include:

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1RKX and 1WVG.

Related Research Articles

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References


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