CEP55

Last updated
CEP55
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CEP55 , C10orf3, CT111, URCC6, centrosomal protein 55, MARCH
External IDs OMIM: 610000; MGI: 1921357; HomoloGene: 10019; GeneCards: CEP55; OMA:CEP55 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001127182
NM_018131

NM_001164362
NM_028293
NM_028760
NM_001360663

RefSeq (protein)

NP_001120654
NP_060601

NP_001157834
NP_082569
NP_083036
NP_001347592

Location (UCSC) Chr 10: 93.5 – 93.53 Mb Chr 19: 38.04 – 38.06 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Centrosomal protein of 55 kDa(Cep55), is a protein that in humans is encoded by the CEP55 gene. [5] [6]

Contents

Cep55 is a mitotic phosphoprotein that plays a key role in cytokinesis, the final stage of cell division. [7] and cilia formation in neural stem cells. [8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000138180 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024989 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Fabbro M, Zhou BB, Takahashi M, Sarcevic B, Lal P, Graham ME, Gabrielli BG, Robinson PJ, Nigg EA, Ono Y, Khanna KK (Oct 2005). "Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis". Dev Cell. 9 (4): 477–88. doi: 10.1016/j.devcel.2005.09.003 . PMID   16198290.
  6. "Entrez Gene: CEP55 centrosomal protein 55kDa".
  7. van der Horst A, Simmons J, Khanna KK (November 2009). "Cep55 stabilization is required for normal execution of cytokinesis". Cell Cycle. 8 (22): 3742–3749. doi: 10.4161/cc.8.22.10047 . PMID   19855176.
  8. Behnam Rashidieh; Belal Shohayeb; Amanda Louise Bain; Patrick R. J. Fortuna; Debottam Sinha; Andrew Burgess; Richard Mills; Rachael C. Adams; J. Alejandro Lopez; Peter Blumbergs; John Finnie; Murugan Kalimutho; Michael Piper; James Edward Hudson; Dominic C. H. Ng; Kum Kum Khanna (October 2021). "Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis". PLOS Genetics. 17 (10): e1009334. doi: 10.1371/journal.pgen.1009334 . PMC   8577787 . PMID   34710087.

Further reading