CEP97

Last updated
CEP97
Identifiers
Aliases CEP97 , 2810403B08Rik, LRRIQ2, centrosomal protein 97
External IDs OMIM: 615864 MGI: 1921451 HomoloGene: 11579 GeneCards: CEP97
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001303401
NM_024548

NM_001159364
NM_001159365
NM_001159366
NM_028815

RefSeq (protein)

NP_001290330
NP_078824

NP_001152836
NP_001152837
NP_001152838
NP_083091

Location (UCSC) Chr 3: 101.72 – 101.77 Mb Chr 16: 55.72 – 55.76 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Centrosomal protein of 97 kDa (Cep97), also known as leucine-rich repeat and IQ domain-containing protein 2 (LRRIQ2), is a protein that in humans is encoded by the CEP97 gene. [5]

Contents

Cep97 along with CP110 inhibit generation of cilia. [6]

Related Research Articles

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Centrosome-associated protein CEP250 is a protein that in humans is encoded by the CEP250 gene. This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Furthermore, CEP135 is also required for the centriolar localization of CEP250.

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<span class="mw-page-title-main">CCP110</span> Protein-coding gene in the species Homo sapiens

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000182504 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022604 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: centrosomal protein 97kDa".
  6. Spektor A, Tsang WY, Khoo D, Dynlacht BD (August 2007). "Cep97 and CP110 suppress a cilia assembly program". Cell. 130 (4): 678–690. doi: 10.1016/j.cell.2007.06.027 . PMID   17719545. S2CID   17974875.

Further reading