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chondroitin-sulfate-ABC endolyase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.2.20 | ||||||||
CAS no. | 9024-13-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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chondroitin-sulfate-ABC exolyase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.2.21 | ||||||||
CAS no. | 9024-13-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Chondroitin ABC lyase (EC 4.2.2.20 EC 4.2.2.21, chondroitinase, chondroitin ABC eliminase, chondroitinase ABC) is an enzyme with systematic name chondroitin ABC lyase. [1] [2] This enzyme catalyses the following chemical reaction
This enzyme acts on chondroitin 4-sulfate, chondroitin 6-sulfate and dermatan sulfate.
Following a spinal cord injury, this enzyme can be used to erode scar tissue that can interfere with regeneration. [3]